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Species
Target Symbol
- CD44 (13)
- AKT1 (12)
- FOXM1 (12)
- STAT3 (11)
- EGFR (10)
- HNF 4 ALPHA (10)
- IRF5 (10)
- KRAS (10)
- AMYLOID PRECURSOR PROTEIN (9)
- GATA2 (9)
- ISOCITRATE DEHYDROGENASE (9)
- P53 (9)
- P63 (9)
- VEGFA (9)
- DNMT3A (8)
- MET (8)
- MU OPIOID RECEPTOR (8)
- RAB5 (8)
- SOD2 (8)
- SPHK1 (8)
- TMEM16A (8)
- TRPA1 (8)
- UCP2 (8)
- ABCG2 (7)
- BIRC5 (7)
- CREB1 (7)
- CXCR4 (7)
- DNMT1 (7)
- FGFR2 (7)
- GPBAR1 (7)
- LAMP2 (7)
- MGMT (7)
- MITF (7)
- PD-L1 (7)
- PPAR GAMMA (7)
- RUNX2 (7)
- SIRT1 (7)
- SLC22A12 (7)
- SLC22A6 (7)
- VR1 (7)
- ADAM17 (6)
- ADAR1 (6)
- ALDH1A1 (6)
- APOLIPOPROTEIN L 1 (6)
- ARF1 (6)
- BACE1 (6)
- BMP7 (6)
- BRG1 (6)
- CD163 (6)
- CD63 (6)
- CERAMIDE SYNTHASE 2 (6)
- CHRNA3 (6)
- CONSTITUTIVE ANDROSTANE RECEPTOR (6)
- CTLA4 (6)
- DDIT3 (6)
- E2F1 (6)
- ERK2 (6)
- EZH2 (6)
- FGFR1 (6)
- FOXA2 (6)
- GAPDH (6)
- GLUCOCORTICOID RECEPTOR (6)
- HER2 (6)
- HIF-1 ALPHA (6)
- IRF1 (6)
- KLF4 (6)
- LAMP1 (6)
- LCK (6)
- LDHA (6)
- MCL1 (6)
- MLH1 (6)
- NLRP3 (6)
- NOR1 (6)
- NUMB (6)
- ORAI1 (6)
- P21 (6)
- PODXL (6)
- PRKACA (6)
- SIRT3 (6)
- SOX11 (6)
- SOX2 (6)
- SOX6 (6)
- SQSTM1 (6)
- STAT1 (6)
- TLR4 (6)
- TRPV4 (6)
- ALPHA 1 ANTITRYPSIN (5)
- ANNEXIN A2 (5)
- APE1 (5)
- AREB6 (5)
- ASS1 (5)
- ATG16L1 (5)
- ATG5 (5)
- BCL2 (5)
- BDNF (5)
- BETA CATENIN (5)
- BMI1 (5)
- CAMK2A (5)
- CASPASE 3 (5)
- CATHEPSIN L (5)
Tags
Vectors
- pCMV6-Entry (6118)
- pCMV6-AC-GFP (1566)
- pCMV6-XL5 (1334)
- pCMV6-XL4 (742)
- pCMV6-AC (336)
- PCMV6-Kan/Neo (280)
- pCMV6-XL6 (132)
- PCMV6-Neo (33)
- pCMV6-AC-Myc-DDK (15)
- pCMV6-AN-RFP (5)
- pCMV6-AC-RFP (4)
- pCMV6-AN-GFP (4)
- pCMV6-XL5-DDK-His (4)
- pCMV6-Entry2 (2)
- pCMV6-AC-mGFP (1)
- pCMV6-AC-mRFP (1)
- pCMV6-AN-mRFP (1)
Mutants
Families
- Druggable Genome (4865)
- Transmembrane (2415)
- Transcription Factors (1321)
- Secreted Protein (701)
- ES Cell Differentiation/IPS (551)
- Protein Kinase (490)
- GPCR (273)
- Stem cell - Pluripotency (268)
- Protease (262)
- Adult stem cells (144)
- Embryonic stem cells (114)
- Nuclear Hormone Receptor (107)
- Phosphatase (91)
- Cancer stem cells (86)
- Ion Channels: Potassium (78)
- Induced pluripotent stem cells (76)
- Ion Channels: Other (72)
- P450 (47)
- Stem cell relevant signaling - JAK/STAT signaling pathway (45)
- Ion Channels: Transient receptor potential (43)
- Stem cell relevant signaling - DSL/Notch pathway (43)
- Ion Channels: Cys-loop Receptors (41)
- Stem cell relevant signaling - Wnt Signaling pathway (33)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (24)
- Ion Channels: Sodium (23)
- Ion Channels: Glutamate Receptors (19)
- Ion Channels: ATP Receptors (11)
- Ion Channels: Calcium (9)
- Ion Channels: Cyclic nucleotide gated (2)
- Secreted (1)
Pathways
- Metabolic pathways (618)
- Pathways in cancer (578)
- MAPK signaling pathway (343)
- Focal adhesion (260)
- Neuroactive ligand-receptor interaction (247)
- Cytokine-cytokine receptor interaction (238)
- Regulation of actin cytoskeleton (233)
- Chemokine signaling pathway (221)
- Prostate cancer (209)
- Endocytosis (204)
- Neurotrophin signaling pathway (191)
- Wnt signaling pathway (185)
- Colorectal cancer (180)
- Insulin signaling pathway (179)
- Calcium signaling pathway (177)
- Jak-STAT signaling pathway (177)
- ErbB signaling pathway (169)
- T cell receptor signaling pathway (166)
- Chronic myeloid leukemia (161)
- Melanoma (156)
- Alzheimer's disease (155)
- Axon guidance (152)
- Pancreatic cancer (150)
- Cell cycle (148)
- Toll-like receptor signaling pathway (147)
- Melanogenesis (143)
- Glioma (141)
- Huntington's disease (141)
- Renal cell carcinoma (140)
- Endometrial cancer (139)
- Apoptosis (135)
- Small cell lung cancer (134)
- Leukocyte transendothelial migration (132)
- Natural killer cell mediated cytotoxicity (131)
- Tight junction (131)
- Non-small cell lung cancer (129)
- Acute myeloid leukemia (128)
- Adherens junction (128)
- Cell adhesion molecules (CAMs) (126)
- Fc gamma R-mediated phagocytosis (118)
- VEGF signaling pathway (117)
- GnRH signaling pathway (115)
- Progesterone-mediated oocyte maturation (115)
- Gap junction (114)
- Hematopoietic cell lineage (113)
- TGF-beta signaling pathway (111)
- p53 signaling pathway (111)
- B cell receptor signaling pathway (110)
- Bladder cancer (110)
- Ubiquitin mediated proteolysis (106)
- Adipocytokine signaling pathway (99)
- Fc epsilon RI signaling pathway (99)
- Lysosome (98)
- Vascular smooth muscle contraction (96)
- Oocyte meiosis (91)
- Long-term potentiation (89)
- Basal cell carcinoma (87)
- Purine metabolism (87)
- NOD-like receptor signaling pathway (83)
- Dilated cardiomyopathy (81)
- Epithelial cell signaling in Helicobacter pylori infection (81)
- mTOR signaling pathway (81)
- Long-term depression (80)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (79)
- Parkinson's disease (78)
- Thyroid cancer (78)
- Amyotrophic lateral sclerosis (ALS) (77)
- Hypertrophic cardiomyopathy (HCM) (77)
- RIG-I-like receptor signaling pathway (74)
- Type II diabetes mellitus (73)
- Pathogenic Escherichia coli infection (72)
- PPAR signaling pathway (69)
- Spliceosome (69)
- ECM-receptor interaction (68)
- Antigen processing and presentation (62)
- Metabolism of xenobiotics by cytochrome P450 (61)
- Hedgehog signaling pathway (60)
- Notch signaling pathway (59)
- Glycolysis / Gluconeogenesis (57)
- Cytosolic DNA-sensing pathway (55)
- Viral myocarditis (55)
- Maturity onset diabetes of the young (54)
- Drug metabolism - cytochrome P450 (52)
- Prion diseases (52)
- Systemic lupus erythematosus (52)
- Glutathione metabolism (50)
- Oxidative phosphorylation (50)
- Vibrio cholerae infection (49)
- Dorso-ventral axis formation (48)
- Citrate cycle (TCA cycle) (43)
- Phosphatidylinositol signaling system (43)
- Arachidonic acid metabolism (42)
- Cardiac muscle contraction (42)
- Retinol metabolism (41)
- Arginine and proline metabolism (40)
- Complement and coagulation cascades (40)
- Sphingolipid metabolism (39)
- Pyruvate metabolism (38)
- Type I diabetes mellitus (37)
- Cysteine and methionine metabolism (36)
- Autoimmune thyroid disease (35)
- Inositol phosphate metabolism (34)
- Pyrimidine metabolism (34)
- Primary immunodeficiency (33)
- Glycerophospholipid metabolism (32)
- Tryptophan metabolism (32)
- Allograft rejection (30)
- Androgen and estrogen metabolism (30)
- Base excision repair (30)
- Drug metabolism - other enzymes (29)
- Graft-versus-host disease (29)
- Lysine degradation (29)
- Starch and sucrose metabolism (29)
- Tyrosine metabolism (29)
- Glycerolipid metabolism (28)
- ABC transporters (27)
- Alanine (27)
- Nicotinate and nicotinamide metabolism (27)
- aspartate and glutamate metabolism (27)
- Fatty acid metabolism (26)
- Proteasome (26)
- Regulation of autophagy (26)
- DNA replication (23)
- Olfactory transduction (23)
- Valine (23)
- Mismatch repair (22)
- Fructose and mannose metabolism (21)
- Linoleic acid metabolism (21)
- N-Glycan biosynthesis (21)
- Taste transduction (21)
- Galactose metabolism (20)
- Glycine (19)
- Nitrogen metabolism (19)
- Nucleotide excision repair (19)
- Propanoate metabolism (19)
- RNA degradation (19)
- leucine and isoleucine degradation (19)
- serine and threonine metabolism (19)
- Phenylalanine metabolism (18)
- SNARE interactions in vesicular transport (18)
- Butanoate metabolism (16)
- Homologous recombination (16)
- Pentose phosphate pathway (16)
- Selenoamino acid metabolism (16)
- Amino sugar and nucleotide sugar metabolism (15)
- C21-Steroid hormone metabolism (15)
- Histidine metabolism (15)
- Porphyrin and chlorophyll metabolism (15)
- Renin-angiotensin system (15)
- Ribosome (15)
- Aminoacyl-tRNA biosynthesis (14)
- Asthma (14)
- Ether lipid metabolism (13)
- Glycosaminoglycan degradation (13)
- Steroid biosynthesis (13)
- Glycosphingolipid biosynthesis - lacto and neolacto series (11)
- Ascorbate and aldarate metabolism (10)
- Biosynthesis of unsaturated fatty acids (10)
- Glyoxylate and dicarboxylate metabolism (10)
- Limonene and pinene degradation (10)
- Pantothenate and CoA biosynthesis (10)
- beta-Alanine metabolism (10)
- Glycosphingolipid biosynthesis - globo series (9)
- O-Glycan biosynthesis (9)
- Other glycan degradation (9)
- Heparan sulfate biosynthesis (8)
- Non-homologous end-joining (8)
- Pentose and glucuronate interconversions (8)
- Riboflavin metabolism (8)
- Chondroitin sulfate biosynthesis (7)
- Circadian rhythm - mammal (7)
- Glycosphingolipid biosynthesis - ganglio series (7)
- Keratan sulfate biosynthesis (7)
- Primary bile acid biosynthesis (7)
- leucine and isoleucine biosynthesis (7)
- Folate biosynthesis (6)
- Methane metabolism (6)
- One carbon pool by folate (6)
- RNA polymerase (6)
- Sulfur metabolism (6)
- alpha-Linolenic acid metabolism (6)
- Basal transcription factors (5)
- D-Glutamine and D-glutamate metabolism (5)
- Phenylalanine (4)
- Synthesis and degradation of ketone bodies (4)
- Taurine and hypotaurine metabolism (4)
- tyrosine and tryptophan biosynthesis (4)
- Caffeine metabolism (3)
- Fatty acid elongation in mitochondria (3)
- Terpenoid backbone biosynthesis (3)
- Biotin metabolism (2)
- Cyanoamino acid metabolism (2)
- Fatty acid biosynthesis (2)
- Protein export (2)
- Thiamine metabolism (2)
- D-Arginine and D-ornithine metabolism (1)
- Lipoic acid metabolism (1)
- Lysine biosynthesis (1)
- O-Mannosyl glycan biosynthesis (1)
- Ubiquinone and other terpenoid-quinone biosynthesis (1)
- Vitamin B6 metabolism (1)
