活动过滤器
优化搜索结果
Target Symbol
- MEK1 (11)
- NM23A (10)
- PI 3 KINASE CLASS 2A (9)
- UBE2G2 (9)
- MMP13 (8)
- GTP CYCLOHYDROLASE 1 (7)
- HADHSC (7)
- MEK3 (7)
- RHOJ (7)
- CYTOKERATIN 19 (6)
- DESTRIN (6)
- HER2 (6)
- ORNITHINE CARBAMOYLTRANSFERASE (6)
- PCNA (6)
- SELENIUM BINDING PROTEIN 1 (6)
- SERBP1 (6)
- UBC6E (6)
- AKR1A1 (5)
- CD163 (5)
- LIPG (5)
- MSI1 (5)
- P95 NBS1 (5)
- PDSS2 (5)
- PI 3 KINASE CATALYTIC SUBUNIT GAMMA (5)
- PIM2 (5)
- POGK (5)
- PROCR (5)
- SNAP25 (5)
- THYMIDYLATE SYNTHASE (5)
- UPRT (5)
- ABCD1 (4)
- AGPAT5 (4)
- ARL3 (4)
- BETA CATENIN (4)
- C1S (4)
- CD23 (4)
- CD34 (4)
- CYTOKERATIN 16 (4)
- CYTOKERATIN 20 (4)
- FBXO21 (4)
- IFITM2 (4)
- KALLIKREIN 8 (4)
- KI67 (4)
- MACRO H2A.2 (4)
- P GLYCOPROTEIN (4)
- PARN (4)
- PARVIN ALPHA (4)
- PD1 (4)
- PI 3 KINASE CATALYTIC SUBUNIT ALPHA (4)
- PNMT (4)
- SH3PX1 (4)
- TUBB2B (4)
- AMDHD1 (3)
- AREB6 (3)
- ARMC1 (3)
- B7-1 (3)
- BID (3)
- CD13 (3)
- CD4 (3)
- CD44 (3)
- CD63 (3)
- CD79B (3)
- CONSTITUTIVE ANDROSTANE RECEPTOR (3)
- CYTOCHROME P450 1A2 (3)
- EPM2AIP1 (3)
- ERCC1 (3)
- FBXW7 (3)
- GALECTIN 9 (3)
- GLB1 (3)
- GRANUPHILIN (3)
- GROWTH ARREST SPECIFIC PROTEIN 7 (3)
- IDURONATE 2 SULFATASE (3)
- KINDLIN 2 (3)
- LEUKOTRIENE A4 HYDROLASE (3)
- LGALS3BP (3)
- LYRIC (3)
- MADM (3)
- MAGEA3 (3)
- MDMX (3)
- MEF2C (3)
- MGP (3)
- MONOACYLGLYCEROL LIPASE (3)
- MTOR (3)
- NKX3.1 (3)
- NUDEL (3)
- NUDT12 (3)
- NUMB (3)
- PAX5 (3)
- PTP1B (3)
- RAB30 (3)
- S100A9 (3)
- SENP2 (3)
- SIVA (3)
- STING (3)
- TLE 1 (3)
- TRMT12 (3)
- TTLL12 (3)
- USP5 (3)
- VON WILLEBRAND FACTOR (3)
- ZNF447 (3)
Knockout (KO) Validation
Families
- Druggable Genome (598)
- Transmembrane (167)
- Transcription Factors (116)
- Secreted Protein (79)
- Protein Kinase (68)
- ES Cell Differentiation/IPS (65)
- Protease (58)
- Stem cell - Pluripotency (43)
- Adult stem cells (14)
- Embryonic stem cells (12)
- Nuclear Hormone Receptor (11)
- P450 (10)
- Phosphatase (10)
- Cancer stem cells (7)
- Induced pluripotent stem cells (5)
- Ion Channels: Other (4)
- Stem cell relevant signaling - DSL/Notch pathway (4)
- GPCR (2)
- Stem cell relevant signaling - JAK/STAT signaling pathway (2)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (1)
- Stem cell relevant signaling - Wnt Signaling pathway (1)
Pathways
- Metabolic pathways (154)
- Pathways in cancer (69)
- Focal adhesion (50)
- Prostate cancer (49)
- Toll-like receptor signaling pathway (47)
- MAPK signaling pathway (45)
- ErbB signaling pathway (40)
- Endometrial cancer (39)
- Insulin signaling pathway (39)
- Acute myeloid leukemia (38)
- Fc epsilon RI signaling pathway (38)
- Pancreatic cancer (38)
- T cell receptor signaling pathway (37)
- B cell receptor signaling pathway (36)
- Colorectal cancer (35)
- Non-small cell lung cancer (34)
- Natural killer cell mediated cytotoxicity (33)
- Regulation of actin cytoskeleton (33)
- Chronic myeloid leukemia (32)
- Glioma (32)
- Neurotrophin signaling pathway (32)
- Progesterone-mediated oocyte maturation (32)
- Melanoma (31)
- Fc gamma R-mediated phagocytosis (29)
- VEGF signaling pathway (29)
- Apoptosis (28)
- Renal cell carcinoma (28)
- Gap junction (27)
- Pyrimidine metabolism (27)
- Ubiquitin mediated proteolysis (27)
- Bladder cancer (26)
- Chemokine signaling pathway (26)
- GnRH signaling pathway (26)
- Jak-STAT signaling pathway (25)
- Hematopoietic cell lineage (24)
- Cell adhesion molecules (CAMs) (23)
- Melanogenesis (23)
- Type II diabetes mellitus (23)
- Phosphatidylinositol signaling system (22)
- Inositol phosphate metabolism (21)
- Thyroid cancer (21)
- Oocyte meiosis (20)
- Leukocyte transendothelial migration (19)
- Small cell lung cancer (19)
- mTOR signaling pathway (19)
- Adherens junction (18)
- Amyotrophic lateral sclerosis (ALS) (17)
- Long-term depression (17)
- Long-term potentiation (17)
- Lysosome (17)
- Parkinson's disease (17)
- Pathogenic Escherichia coli infection (17)
- Wnt signaling pathway (17)
- Prion diseases (16)
- Purine metabolism (16)
- Vascular smooth muscle contraction (16)
- Arginine and proline metabolism (15)
- Cytokine-cytokine receptor interaction (15)
- Systemic lupus erythematosus (15)
- Alzheimer's disease (14)
- Complement and coagulation cascades (14)
- Drug metabolism - cytochrome P450 (14)
- Glycerolipid metabolism (14)
- Metabolism of xenobiotics by cytochrome P450 (14)
- Calcium signaling pathway (13)
- Cell cycle (13)
- Dorso-ventral axis formation (13)
- Nucleotide excision repair (13)
- Valine (13)
- leucine and isoleucine degradation (13)
- Glycolysis / Gluconeogenesis (12)
- Tryptophan metabolism (12)
- Arachidonic acid metabolism (11)
- Adipocytokine signaling pathway (10)
- Base excision repair (10)
- Butanoate metabolism (10)
- Retinol metabolism (10)
- p53 signaling pathway (10)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (9)
- Cytosolic DNA-sensing pathway (9)
- DNA replication (9)
- Dilated cardiomyopathy (9)
- Fatty acid metabolism (9)
- Hypertrophic cardiomyopathy (HCM) (9)
- Lysine degradation (9)
- Primary immunodeficiency (9)
- RIG-I-like receptor signaling pathway (9)
- Type I diabetes mellitus (9)
- ABC transporters (8)
- Axon guidance (8)
- ECM-receptor interaction (8)
- Endocytosis (8)
- Folate biosynthesis (8)
- Glutathione metabolism (8)
- Histidine metabolism (8)
- Mismatch repair (8)
- One carbon pool by folate (8)
- RNA degradation (8)
- Renin-angiotensin system (8)
- Tyrosine metabolism (8)
- Viral myocarditis (8)
- Alanine (7)
- Allograft rejection (7)
- Antigen processing and presentation (7)
- Basal cell carcinoma (7)
- Fatty acid elongation in mitochondria (7)
- Glycine (7)
- Graft-versus-host disease (7)
- Huntington's disease (7)
- Sphingolipid metabolism (7)
- aspartate and glutamate metabolism (7)
- serine and threonine metabolism (7)
- Autoimmune thyroid disease (6)
- Epithelial cell signaling in Helicobacter pylori infection (6)
- Glycosaminoglycan degradation (6)
- Homologous recombination (6)
- Other glycan degradation (6)
- SNARE interactions in vesicular transport (6)
- TGF-beta signaling pathway (6)
- Cardiac muscle contraction (5)
- Linoleic acid metabolism (5)
- NOD-like receptor signaling pathway (5)
- Oxidative phosphorylation (5)
- Propanoate metabolism (5)
- Terpenoid backbone biosynthesis (5)
- Tight junction (5)
- Amino sugar and nucleotide sugar metabolism (4)
- Caffeine metabolism (4)
- Glycerophospholipid metabolism (4)
- Neuroactive ligand-receptor interaction (4)
- Nitrogen metabolism (4)
- Notch signaling pathway (4)
- Pantothenate and CoA biosynthesis (4)
- Pyruvate metabolism (4)
- Ribosome (4)
- Starch and sucrose metabolism (4)
- Vibrio cholerae infection (4)
- beta-Alanine metabolism (4)
- Circadian rhythm - mammal (3)
- Cysteine and methionine metabolism (3)
- Galactose metabolism (3)
- Glycosphingolipid biosynthesis - ganglio series (3)
- Hedgehog signaling pathway (3)
- Nicotinate and nicotinamide metabolism (3)
- Proteasome (3)
- Regulation of autophagy (3)
- Taste transduction (3)
- Asthma (2)
- Cyanoamino acid metabolism (2)
- Maturity onset diabetes of the young (2)
- PPAR signaling pathway (2)
- Phenylalanine metabolism (2)
- Porphyrin and chlorophyll metabolism (2)
- RNA polymerase (2)
- Spliceosome (2)
- Vitamin B6 metabolism (2)
- Aminoacyl-tRNA biosynthesis (1)
- Ascorbate and aldarate metabolism (1)
- D-Glutamine and D-glutamate metabolism (1)
- Drug metabolism - other enzymes (1)
- Glycosphingolipid biosynthesis - lacto and neolacto series (1)
- Glyoxylate and dicarboxylate metabolism (1)
- Keratan sulfate biosynthesis (1)
- Methane metabolism (1)
- N-Glycan biosynthesis (1)
- Pentose phosphate pathway (1)
- Steroid biosynthesis (1)
- Synthesis and degradation of ketone bodies (1)
- Taurine and hypotaurine metabolism (1)
- Thiamine metabolism (1)
- leucine and isoleucine biosynthesis (1)