Expression Plasmids

cDNA Clones

Expression Plasmids

Human

AKR1C2

ALDH3A1

UGT

AKR1C1

AKR1C3

CYP1B1

CYP3A43

CYTOCHROME P450 2C19

EPOXIDE HYDROLASE

ADH1B

ADH4

ADH5

ADH6

ALDH1A3

CYP1A1

CYTOCHROME P450 1A2

CYTOCHROME P450 2B6

CYTOCHROME P450 2C8

CYTOCHROME P450 2C9

CYTOCHROME P450 2E1

CYTOCHROME P450 3A4

CYTOCHROME P450 3A5

GLUTATHIONE S TRANSFERASE OMEGA 1

GST3

GSTM1

MGST2

Plasmids

Myc-DDK

mGFP

pLenti-C-Myc-DDK

pLenti-C-mGFP

No

LentiORF

Druggable Genome

Transmembrane

P450

Protease

ES Cell Differentiation/IPS

Pathways in cancer

Metabolic pathways

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Focal adhesion

Chemokine signaling pathway

Regulation of actin cytoskeleton

Neurotrophin signaling pathway

Jak-STAT signaling pathway

Calcium signaling pathway

Wnt signaling pathway

Natural killer cell mediated cytotoxicity

Insulin signaling pathway

T cell receptor signaling pathway

Toll-like receptor signaling pathway

Prostate cancer

ErbB signaling pathway

Colorectal cancer

Apoptosis

Endocytosis

Pancreatic cancer

Axon guidance

Progesterone-mediated oocyte maturation

Leukocyte transendothelial migration

Chronic myeloid leukemia

B cell receptor signaling pathway

Cell cycle

Melanoma

GnRH signaling pathway

Small cell lung cancer

Melanogenesis

Cell adhesion molecules (CAMs)

Fc epsilon RI signaling pathway

VEGF signaling pathway

Adherens junction

Alzheimer's disease

Oocyte meiosis

Renal cell carcinoma

Glioma

Hematopoietic cell lineage

TGF-beta signaling pathway

Gap junction

Adipocytokine signaling pathway

Tight junction

Vascular smooth muscle contraction

Acute myeloid leukemia

Ubiquitin mediated proteolysis

Fc gamma R-mediated phagocytosis

Non-small cell lung cancer

NOD-like receptor signaling pathway

Endometrial cancer

Huntington's disease

Long-term potentiation

p53 signaling pathway

RIG-I-like receptor signaling pathway

Bladder cancer

Dilated cardiomyopathy

Hypertrophic cardiomyopathy (HCM)

Purine metabolism

Type II diabetes mellitus

Amyotrophic lateral sclerosis (ALS)

Long-term depression

Epithelial cell signaling in Helicobacter pylori infection

Lysosome

Complement and coagulation cascades

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

mTOR signaling pathway

ECM-receptor interaction

Basal cell carcinoma

Hedgehog signaling pathway

Phosphatidylinositol signaling system

Pathogenic Escherichia coli infection

Thyroid cancer

Glycolysis / Gluconeogenesis

Viral myocarditis

Cytosolic DNA-sensing pathway

PPAR signaling pathway

Parkinson's disease

Primary immunodeficiency

Antigen processing and presentation

Metabolism of xenobiotics by cytochrome P450

Autoimmune thyroid disease

Retinol metabolism

Vibrio cholerae infection

Arginine and proline metabolism

Notch signaling pathway

Olfactory transduction

Systemic lupus erythematosus

ABC transporters

Arachidonic acid metabolism

Lysine degradation

Prion diseases

Inositol phosphate metabolism

Maturity onset diabetes of the young

Nucleotide excision repair

Drug metabolism - cytochrome P450

Pyruvate metabolism

Regulation of autophagy

Pyrimidine metabolism

Valine

Base excision repair

Cardiac muscle contraction

Tyrosine metabolism

Sphingolipid metabolism

Taste transduction

Type I diabetes mellitus

Fructose and mannose metabolism

Tryptophan metabolism

leucine and isoleucine degradation

Dorso-ventral axis formation

Drug metabolism - other enzymes

Galactose metabolism

Glutathione metabolism

Starch and sucrose metabolism

Allograft rejection

Glycerophospholipid metabolism

Cysteine and methionine metabolism

Amino sugar and nucleotide sugar metabolism

Citrate cycle (TCA cycle)

Fatty acid metabolism

Glycerolipid metabolism

Propanoate metabolism

Renin-angiotensin system

Homologous recombination

Linoleic acid metabolism

Androgen and estrogen metabolism

Graft-versus-host disease

Circadian rhythm - mammal

Nitrogen metabolism

Spliceosome

Ether lipid metabolism

Pentose phosphate pathway

Phenylalanine metabolism

Proteasome

Alanine

Butanoate metabolism

Histidine metabolism

SNARE interactions in vesicular transport

aspartate and glutamate metabolism

Mismatch repair

Oxidative phosphorylation

Glycosaminoglycan degradation

Porphyrin and chlorophyll metabolism

Asthma

DNA replication

Glycine

Riboflavin metabolism

serine and threonine metabolism

Non-homologous end-joining

Other glycan degradation

Ribosome

Steroid biosynthesis

beta-Alanine metabolism

C21-Steroid hormone metabolism

Folate biosynthesis

Glycosphingolipid biosynthesis - globo series

N-Glycan biosynthesis

Primary bile acid biosynthesis

Basal transcription factors

Aminoacyl-tRNA biosynthesis

Ascorbate and aldarate metabolism

Limonene and pinene degradation

Nicotinate and nicotinamide metabolism

Terpenoid backbone biosynthesis

alpha-Linolenic acid metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Glyoxylate and dicarboxylate metabolism

One carbon pool by folate

Pantothenate and CoA biosynthesis

Selenoamino acid metabolism

leucine and isoleucine biosynthesis

Glycosphingolipid biosynthesis - ganglio series

Methane metabolism

Pentose and glucuronate interconversions

RNA degradation

Biosynthesis of unsaturated fatty acids

Thiamine metabolism

Caffeine metabolism

Fatty acid biosynthesis

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

O-Glycan biosynthesis

Protein export

Taurine and hypotaurine metabolism

Fatty acid elongation in mitochondria

Heparan sulfate biosynthesis

Keratan sulfate biosynthesis

Synthesis and degradation of ketone bodies

Ubiquinone and other terpenoid-quinone biosynthesis

Vitamin B6 metabolism

D-Arginine and D-ornithine metabolism

D-Glutamine and D-glutamate metabolism

Phenylalanine

Sulfur metabolism

tyrosine and tryptophan biosynthesis

None

Puromycin

1

Yes

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