Expression Plasmids

cDNA Clones

Expression Plasmids

Human

RRM2

TXNRD1

DCK

POLD1

THYMIDYLATE SYNTHASE

UCK2

DTYMK

DUT

NM23A

THYMIDINE KINASE 1

UMPS

AK3

CMPK1

DPYD

INOSINE TRIPHOSPHATE PYROPHOSPHATASE

NME2

NME3

NME4

POLE

RRM1

THYMIDINE KINASE 2

THYMIDINE PHOSPHORYLASE

UCK

Plasmids

Myc-DDK

mGFP

pLenti-C-Myc-DDK

pLenti-C-mGFP-P2A-Puro

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP

No

LentiORF

Druggable Genome

Stem cell - Pluripotency

Transcription Factors

Transmembrane

ES Cell Differentiation/IPS

Pathways in cancer

Metabolic pathways

Cytokine-cytokine receptor interaction

MAPK signaling pathway

Neuroactive ligand-receptor interaction

Focal adhesion

Chemokine signaling pathway

Regulation of actin cytoskeleton

Neurotrophin signaling pathway

Jak-STAT signaling pathway

Calcium signaling pathway

Prostate cancer

Wnt signaling pathway

T cell receptor signaling pathway

Toll-like receptor signaling pathway

Insulin signaling pathway

Natural killer cell mediated cytotoxicity

Colorectal cancer

ErbB signaling pathway

Pancreatic cancer

Endocytosis

Chronic myeloid leukemia

Apoptosis

Cell cycle

Melanoma

Axon guidance

Cell adhesion molecules (CAMs)

Small cell lung cancer

Progesterone-mediated oocyte maturation

Hematopoietic cell lineage

B cell receptor signaling pathway

Leukocyte transendothelial migration

Glioma

Renal cell carcinoma

Adherens junction

Fc epsilon RI signaling pathway

TGF-beta signaling pathway

Oocyte meiosis

Alzheimer's disease

Melanogenesis

VEGF signaling pathway

GnRH signaling pathway

Acute myeloid leukemia

Adipocytokine signaling pathway

Non-small cell lung cancer

Gap junction

Tight junction

Endometrial cancer

Vascular smooth muscle contraction

Bladder cancer

Ubiquitin mediated proteolysis

NOD-like receptor signaling pathway

p53 signaling pathway

Fc gamma R-mediated phagocytosis

Huntington's disease

Long-term potentiation

RIG-I-like receptor signaling pathway

Hypertrophic cardiomyopathy (HCM)

Dilated cardiomyopathy

Epithelial cell signaling in Helicobacter pylori infection

Amyotrophic lateral sclerosis (ALS)

Long-term depression

Type II diabetes mellitus

ECM-receptor interaction

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

mTOR signaling pathway

Purine metabolism

Lysosome

Complement and coagulation cascades

Thyroid cancer

Basal cell carcinoma

PPAR signaling pathway

Hedgehog signaling pathway

Cytosolic DNA-sensing pathway

Pathogenic Escherichia coli infection

Glycolysis / Gluconeogenesis

Phosphatidylinositol signaling system

Viral myocarditis

Parkinson's disease

Primary immunodeficiency

Antigen processing and presentation

Metabolism of xenobiotics by cytochrome P450

Autoimmune thyroid disease

Arginine and proline metabolism

Maturity onset diabetes of the young

Arachidonic acid metabolism

ABC transporters

Prion diseases

Notch signaling pathway

Nucleotide excision repair

Systemic lupus erythematosus

Lysine degradation

Pyruvate metabolism

Retinol metabolism

Vibrio cholerae infection

Type I diabetes mellitus

Base excision repair

Drug metabolism - cytochrome P450

Allograft rejection

Regulation of autophagy

Valine

Olfactory transduction

Sphingolipid metabolism

Dorso-ventral axis formation

Inositol phosphate metabolism

Tryptophan metabolism

Tyrosine metabolism

Cysteine and methionine metabolism

Glycerolipid metabolism

Pyrimidine metabolism

Glycerophospholipid metabolism

Graft-versus-host disease

leucine and isoleucine degradation

Fructose and mannose metabolism

Galactose metabolism

Glutathione metabolism

Cardiac muscle contraction

Homologous recombination

Linoleic acid metabolism

Citrate cycle (TCA cycle)

Fatty acid metabolism

Starch and sucrose metabolism

Drug metabolism - other enzymes

Taste transduction

Propanoate metabolism

Renin-angiotensin system

Amino sugar and nucleotide sugar metabolism

Circadian rhythm - mammal

Butanoate metabolism

Mismatch repair

Proteasome

Androgen and estrogen metabolism

Ether lipid metabolism

Glycosaminoglycan degradation

Nitrogen metabolism

SNARE interactions in vesicular transport

Asthma

Other glycan degradation

DNA replication

Phenylalanine metabolism

Alanine

Histidine metabolism

Pentose phosphate pathway

aspartate and glutamate metabolism

Glycine

beta-Alanine metabolism

serine and threonine metabolism

Oxidative phosphorylation

Ribosome

Spliceosome

Steroid biosynthesis

Non-homologous end-joining

C21-Steroid hormone metabolism

Folate biosynthesis

Porphyrin and chlorophyll metabolism

Glycosphingolipid biosynthesis - globo series

Nicotinate and nicotinamide metabolism

Riboflavin metabolism

Limonene and pinene degradation

Ascorbate and aldarate metabolism

N-Glycan biosynthesis

alpha-Linolenic acid metabolism

Glycosphingolipid biosynthesis - ganglio series

Primary bile acid biosynthesis

leucine and isoleucine biosynthesis

Glyoxylate and dicarboxylate metabolism

Aminoacyl-tRNA biosynthesis

Methane metabolism

Pantothenate and CoA biosynthesis

Glycosphingolipid biosynthesis - lacto and neolacto series

One carbon pool by folate

Pentose and glucuronate interconversions

RNA degradation

Selenoamino acid metabolism

Terpenoid backbone biosynthesis

Basal transcription factors

Biosynthesis of unsaturated fatty acids

Heparan sulfate biosynthesis

Synthesis and degradation of ketone bodies

Thiamine metabolism

Caffeine metabolism

Fatty acid elongation in mitochondria

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Keratan sulfate biosynthesis

O-Glycan biosynthesis

Fatty acid biosynthesis

Phenylalanine

Protein export

Taurine and hypotaurine metabolism

Vitamin B6 metabolism

tyrosine and tryptophan biosynthesis

D-Arginine and D-ornithine metabolism

D-Glutamine and D-glutamate metabolism

Sulfur metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

None

Puromycin

1

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