Expression Plasmids

cDNA Clones

Expression Plasmids

Human

IKK GAMMA

PML PROTEIN

RETINOIC ACID RECEPTOR ALPHA

RUNX1

TCF7L2

AKT1

AKT3

ERK2

GRB2

KRAS

NFKB1

P21 RAS

PI 3 KINASE P55 GAMMA

PI 3 KINASE P85 ALPHA

RUNX1T1

SPI1

STAT3

A RAF

AKT2

B RAF

BAD

BMP2

C-MYC

CD117

CEBP ALPHA

CYCLIN A1

CYCLIN D1

EIF4EBP1

ERK1

FLT3

IKK ALPHA

IKK BETA

LEF1

MEK1

MEK2

MTOR

NF-KB P65

NRAS

P70 S6 KINASE BETA

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

PI 3 KINASE CATALYTIC SUBUNIT GAMMA

PI 3 KINASE P85 BETA

PIK3CB

PIK3CD

PIK3R5

PIM1

PIM2

PLZF

PPAR DELTA

RAF1

S6K1

SKP2

SOS1

STAT5A

STAT5B

TCF7

Plasmids

Myc-DDK

pCMV6-Entry

pCMV6-AC-GFP

pLenti-C-Myc-DDK

pLenti-C-mGFP-P2A-Puro

pCMV6-XL5

pCMV6-XL4

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP

pCMV6-AC

pCMV6-XL6

pCMV6-XL5-DDK-His

No

LentiORF

Druggable Genome

Transcription Factors

Protein Kinase

ES Cell Differentiation/IPS

Nuclear Hormone Receptor

Stem cell relevant signaling - JAK/STAT signaling pathway

Adult stem cells

Embryonic stem cells

Stem cell - Pluripotency

Transmembrane

Induced pluripotent stem cells

Stem cell relevant signaling - DSL/Notch pathway

Stem cell relevant signaling - TGFb/BMP signaling pathway

Stem cell relevant signaling - Wnt Signaling pathway

Cancer stem cells

Secreted Protein

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Regulation of actin cytoskeleton

Focal adhesion

Chemokine signaling pathway

Neurotrophin signaling pathway

Wnt signaling pathway

Endocytosis

Calcium signaling pathway

Jak-STAT signaling pathway

Natural killer cell mediated cytotoxicity

Insulin signaling pathway

Toll-like receptor signaling pathway

Leukocyte transendothelial migration

Ubiquitin mediated proteolysis

T cell receptor signaling pathway

Alzheimer's disease

Cell adhesion molecules (CAMs)

Axon guidance

ErbB signaling pathway

Prostate cancer

Huntington's disease

Melanogenesis

Progesterone-mediated oocyte maturation

Apoptosis

Tight junction

Cell cycle

Colorectal cancer

Oocyte meiosis

GnRH signaling pathway

Pancreatic cancer

Chronic myeloid leukemia

Fc gamma R-mediated phagocytosis

Vascular smooth muscle contraction

B cell receptor signaling pathway

Adherens junction

Fc epsilon RI signaling pathway

Melanoma

Purine metabolism

Small cell lung cancer

Hematopoietic cell lineage

VEGF signaling pathway

TGF-beta signaling pathway

Renal cell carcinoma

Gap junction

Lysosome

RIG-I-like receptor signaling pathway

Glioma

Acute myeloid leukemia

NOD-like receptor signaling pathway

Adipocytokine signaling pathway

Parkinson's disease

Long-term potentiation

Dilated cardiomyopathy

p53 signaling pathway

Non-small cell lung cancer

Spliceosome

Endometrial cancer

Hypertrophic cardiomyopathy (HCM)

Antigen processing and presentation

Amyotrophic lateral sclerosis (ALS)

Epithelial cell signaling in Helicobacter pylori infection

Systemic lupus erythematosus

Long-term depression

mTOR signaling pathway

Type II diabetes mellitus

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Hedgehog signaling pathway

PPAR signaling pathway

Viral myocarditis

Basal cell carcinoma

Bladder cancer

Complement and coagulation cascades

ECM-receptor interaction

Cytosolic DNA-sensing pathway

Oxidative phosphorylation

Glycolysis / Gluconeogenesis

Pathogenic Escherichia coli infection

Phosphatidylinositol signaling system

Vibrio cholerae infection

Arginine and proline metabolism

Ribosome

Pyrimidine metabolism

Autoimmune thyroid disease

Metabolism of xenobiotics by cytochrome P450

Glycerophospholipid metabolism

Notch signaling pathway

Retinol metabolism

Thyroid cancer

Cardiac muscle contraction

Olfactory transduction

Lysine degradation

Drug metabolism - cytochrome P450

Primary immunodeficiency

Type I diabetes mellitus

Arachidonic acid metabolism

Valine

Nucleotide excision repair

Regulation of autophagy

Tryptophan metabolism

Prion diseases

Sphingolipid metabolism

Starch and sucrose metabolism

Tyrosine metabolism

Maturity onset diabetes of the young

leucine and isoleucine degradation

Allograft rejection

Amino sugar and nucleotide sugar metabolism

Drug metabolism - other enzymes

Graft-versus-host disease

Inositol phosphate metabolism

N-Glycan biosynthesis

Proteasome

Pyruvate metabolism

ABC transporters

Glutathione metabolism

RNA degradation

Fructose and mannose metabolism

Taste transduction

Glycerolipid metabolism

Cysteine and methionine metabolism

Dorso-ventral axis formation

Base excision repair

Citrate cycle (TCA cycle)

Androgen and estrogen metabolism

Fatty acid metabolism

Propanoate metabolism

Ether lipid metabolism

Galactose metabolism

SNARE interactions in vesicular transport

Alanine

aspartate and glutamate metabolism

Asthma

Glycine

Linoleic acid metabolism

serine and threonine metabolism

Butanoate metabolism

DNA replication

Glycosphingolipid biosynthesis - lacto and neolacto series

Glycosaminoglycan degradation

Histidine metabolism

Homologous recombination

Nitrogen metabolism

Pentose phosphate pathway

Porphyrin and chlorophyll metabolism

O-Glycan biosynthesis

Phenylalanine metabolism

Biosynthesis of unsaturated fatty acids

Renin-angiotensin system

beta-Alanine metabolism

Circadian rhythm - mammal

Aminoacyl-tRNA biosynthesis

Heparan sulfate biosynthesis

Nicotinate and nicotinamide metabolism

Mismatch repair

Non-homologous end-joining

Ascorbate and aldarate metabolism

One carbon pool by folate

Riboflavin metabolism

Steroid biosynthesis

alpha-Linolenic acid metabolism

Basal transcription factors

Glycosphingolipid biosynthesis - ganglio series

Glycosphingolipid biosynthesis - globo series

Limonene and pinene degradation

Other glycan degradation

Pentose and glucuronate interconversions

Primary bile acid biosynthesis

Selenoamino acid metabolism

Terpenoid backbone biosynthesis

C21-Steroid hormone metabolism

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Glyoxylate and dicarboxylate metabolism

Keratan sulfate biosynthesis

RNA polymerase

Folate biosynthesis

Protein export

Methane metabolism

Pantothenate and CoA biosynthesis

Sulfur metabolism

Chondroitin sulfate biosynthesis

Fatty acid elongation in mitochondria

Thiamine metabolism

leucine and isoleucine biosynthesis

Cyanoamino acid metabolism

Taurine and hypotaurine metabolism

Caffeine metabolism

Fatty acid biosynthesis

Synthesis and degradation of ketone bodies

Vitamin B6 metabolism

D-Glutamine and D-glutamate metabolism

Phenylalanine

Ubiquinone and other terpenoid-quinone biosynthesis

tyrosine and tryptophan biosynthesis

Biotin metabolism

D-Arginine and D-ornithine metabolism

Lipoic acid metabolism

Lysine biosynthesis

O-Mannosyl glycan biosynthesis

None

1

Yes

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