Expression Plasmids

cDNA Clones

Expression Plasmids

Human

P53

CDK1

CDC45L

CDC7

CHK1

CHK2

CDC25C

CYCLIN E1

MCM4

ORC1

PCNA

WEE1

BUBR1

C-MYC

CDK7

CYCLIN A2

CYCLIN B1

CYCLIN B2

CYCLIN D1

GADD45A

HDAC1

HDAC2

MCM2

MCM3

MCM5

MCM6

ORC2

ORC6L

Plasmids

Myc-DDK

mGFP

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP-P2A-Puro

No

LentiORF

Druggable Genome

Transcription Factors

Stem cell - Pluripotency

Protein Kinase

Phosphatase

Stem cell relevant signaling - JAK/STAT signaling pathway

ES Cell Differentiation/IPS

Embryonic stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Cancer stem cells

Secreted Protein

Stem cell relevant signaling - DSL/Notch pathway

Transmembrane

Stem cell relevant signaling - Wnt Signaling pathway

Adult stem cells

Induced pluripotent stem cells

Cell cycle

Metabolic pathways

Pathways in cancer

p53 signaling pathway

Spliceosome

DNA replication

Mismatch repair

MAPK signaling pathway

Nucleotide excision repair

Base excision repair

Colorectal cancer

Small cell lung cancer

Focal adhesion

RNA degradation

Oocyte meiosis

Homologous recombination

Prostate cancer

Regulation of actin cytoskeleton

T cell receptor signaling pathway

Amyotrophic lateral sclerosis (ALS)

Chronic myeloid leukemia

Huntington's disease

Pancreatic cancer

Purine metabolism

Apoptosis

Pyrimidine metabolism

Wnt signaling pathway

Endometrial cancer

ErbB signaling pathway

Neurotrophin signaling pathway

Non-small cell lung cancer

Progesterone-mediated oocyte maturation

Axon guidance

Bladder cancer

Thyroid cancer

Glioma

Jak-STAT signaling pathway

Melanoma

Renal cell carcinoma

Basal cell carcinoma

Chemokine signaling pathway

Natural killer cell mediated cytotoxicity

Endocytosis

Antigen processing and presentation

Cytosolic DNA-sensing pathway

Fc gamma R-mediated phagocytosis

Gap junction

Glycerophospholipid metabolism

Prion diseases

Proteasome

B cell receptor signaling pathway

Cysteine and methionine metabolism

Notch signaling pathway

Systemic lupus erythematosus

Ubiquitin mediated proteolysis

VEGF signaling pathway

Drug metabolism - other enzymes

ECM-receptor interaction

Leukocyte transendothelial migration

Non-homologous end-joining

Primary immunodeficiency

RNA polymerase

Viral myocarditis

Acute myeloid leukemia

Cytokine-cytokine receptor interaction

Adherens junction

Alzheimer's disease

Calcium signaling pathway

Ether lipid metabolism

Glycerolipid metabolism

Insulin signaling pathway

NOD-like receptor signaling pathway

One carbon pool by folate

Parkinson's disease

Pathogenic Escherichia coli infection

SNARE interactions in vesicular transport

Selenoamino acid metabolism

Sphingolipid metabolism

TGF-beta signaling pathway

Adipocytokine signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

Fructose and mannose metabolism

Glycolysis / Gluconeogenesis

Pentose phosphate pathway

RIG-I-like receptor signaling pathway

Type I diabetes mellitus

Hematopoietic cell lineage

Melanogenesis

Alanine

Arginine and proline metabolism

Basal transcription factors

Cardiac muscle contraction

Dilated cardiomyopathy

Folate biosynthesis

Glycine

Glyoxylate and dicarboxylate metabolism

Hypertrophic cardiomyopathy (HCM)

Nicotinate and nicotinamide metabolism

Phenylalanine

Phenylalanine metabolism

Steroid biosynthesis

Type II diabetes mellitus

Tyrosine metabolism

aspartate and glutamate metabolism

serine and threonine metabolism

tyrosine and tryptophan biosynthesis

Puromycin

None

1

Yes

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