Expression Plasmids

cDNA Clones

Expression Plasmids

Human

APH1A

DELTEX

DISHEVELLED 2

DISHEVELLED 3

DLL3

DLL4

DTX3

DTX3L

DVL1

EP300

HDAC1

HDAC2

HES1

HES5

JAGGED 2

JAGGED1

KAT2B

KAT3A / CBP

MAML2

MANIC FRINGE

NCOA62

NCOR2

NICASTRIN

NOTCH3

NOTCH4

PEN2

PRESENILIN 1

PRESENILIN 2

Plasmids

Myc-DDK

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-Myc-DDK

No

LentiORF

Druggable Genome

Transcription Factors

Transmembrane

ES Cell Differentiation/IPS

Stem cell relevant signaling - DSL/Notch pathway

Cancer stem cells

Adult stem cells

Stem cell - Pluripotency

Protease

Stem cell relevant signaling - Wnt Signaling pathway

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Focal adhesion

Chemokine signaling pathway

Regulation of actin cytoskeleton

Neurotrophin signaling pathway

Calcium signaling pathway

Jak-STAT signaling pathway

Wnt signaling pathway

Insulin signaling pathway

Natural killer cell mediated cytotoxicity

T cell receptor signaling pathway

Toll-like receptor signaling pathway

ErbB signaling pathway

Progesterone-mediated oocyte maturation

Endocytosis

Prostate cancer

Colorectal cancer

Apoptosis

Axon guidance

Pancreatic cancer

GnRH signaling pathway

Oocyte meiosis

Cell cycle

Leukocyte transendothelial migration

Alzheimer's disease

Melanogenesis

Chronic myeloid leukemia

B cell receptor signaling pathway

Small cell lung cancer

Vascular smooth muscle contraction

VEGF signaling pathway

Gap junction

Adherens junction

Cell adhesion molecules (CAMs)

Renal cell carcinoma

Fc epsilon RI signaling pathway

Melanoma

TGF-beta signaling pathway

Hematopoietic cell lineage

Ubiquitin mediated proteolysis

Glioma

NOD-like receptor signaling pathway

Adipocytokine signaling pathway

Tight junction

Acute myeloid leukemia

Long-term potentiation

Fc gamma R-mediated phagocytosis

Dilated cardiomyopathy

Huntington's disease

Non-small cell lung cancer

Purine metabolism

RIG-I-like receptor signaling pathway

p53 signaling pathway

Endometrial cancer

Hypertrophic cardiomyopathy (HCM)

Long-term depression

Type II diabetes mellitus

Amyotrophic lateral sclerosis (ALS)

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Bladder cancer

Epithelial cell signaling in Helicobacter pylori infection

Lysosome

Complement and coagulation cascades

ECM-receptor interaction

mTOR signaling pathway

Hedgehog signaling pathway

Phosphatidylinositol signaling system

Basal cell carcinoma

Glycolysis / Gluconeogenesis

Pathogenic Escherichia coli infection

Cytosolic DNA-sensing pathway

PPAR signaling pathway

Parkinson's disease

Thyroid cancer

Viral myocarditis

ABC transporters

Antigen processing and presentation

Arginine and proline metabolism

Primary immunodeficiency

Metabolism of xenobiotics by cytochrome P450

Retinol metabolism

Cardiac muscle contraction

Olfactory transduction

Lysine degradation

Nucleotide excision repair

Autoimmune thyroid disease

Drug metabolism - cytochrome P450

Notch signaling pathway

Vibrio cholerae infection

Inositol phosphate metabolism

Valine

Arachidonic acid metabolism

Prion diseases

Pyrimidine metabolism

Pyruvate metabolism

Base excision repair

Regulation of autophagy

Taste transduction

Tyrosine metabolism

Drug metabolism - other enzymes

Systemic lupus erythematosus

leucine and isoleucine degradation

Maturity onset diabetes of the young

Starch and sucrose metabolism

Tryptophan metabolism

Fructose and mannose metabolism

Type I diabetes mellitus

Galactose metabolism

Glycerophospholipid metabolism

Sphingolipid metabolism

Amino sugar and nucleotide sugar metabolism

Cysteine and methionine metabolism

Androgen and estrogen metabolism

Dorso-ventral axis formation

Fatty acid metabolism

Glutathione metabolism

Glycerolipid metabolism

Propanoate metabolism

Allograft rejection

Citrate cycle (TCA cycle)

Homologous recombination

Linoleic acid metabolism

Renin-angiotensin system

Spliceosome

Histidine metabolism

Mismatch repair

Nitrogen metabolism

Oxidative phosphorylation

Alanine

Butanoate metabolism

Ether lipid metabolism

Graft-versus-host disease

Pentose phosphate pathway

Phenylalanine metabolism

Proteasome

SNARE interactions in vesicular transport

aspartate and glutamate metabolism

Circadian rhythm - mammal

Glycosaminoglycan degradation

DNA replication

Glycine

Non-homologous end-joining

Porphyrin and chlorophyll metabolism

serine and threonine metabolism

Ribosome

beta-Alanine metabolism

C21-Steroid hormone metabolism

Other glycan degradation

Riboflavin metabolism

Asthma

Primary bile acid biosynthesis

Steroid biosynthesis

Aminoacyl-tRNA biosynthesis

Folate biosynthesis

N-Glycan biosynthesis

Ascorbate and aldarate metabolism

Basal transcription factors

Glycosphingolipid biosynthesis - globo series

Terpenoid backbone biosynthesis

alpha-Linolenic acid metabolism

Glyoxylate and dicarboxylate metabolism

Limonene and pinene degradation

Nicotinate and nicotinamide metabolism

Pantothenate and CoA biosynthesis

Pentose and glucuronate interconversions

leucine and isoleucine biosynthesis

Glycosphingolipid biosynthesis - lacto and neolacto series

One carbon pool by folate

RNA degradation

Selenoamino acid metabolism

Biosynthesis of unsaturated fatty acids

Glycosphingolipid biosynthesis - ganglio series

Methane metabolism

Thiamine metabolism

Caffeine metabolism

Fatty acid biosynthesis

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Protein export

Taurine and hypotaurine metabolism

Fatty acid elongation in mitochondria

Heparan sulfate biosynthesis

O-Glycan biosynthesis

Synthesis and degradation of ketone bodies

Ubiquinone and other terpenoid-quinone biosynthesis

Vitamin B6 metabolism

D-Arginine and D-ornithine metabolism

D-Glutamine and D-glutamate metabolism

Keratan sulfate biosynthesis

Phenylalanine

Sulfur metabolism

tyrosine and tryptophan biosynthesis

None

1

Yes

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