Expression Plasmids

cDNA Clones

Expression Plasmids

Human

P53

EVI1

ACTIVIN A RECEPTOR TYPE IC

IKK GAMMA

MDM2

P16INK4A

SHC

SMAD3

ACTIVIN A RECEPTOR TYPE IB

AKT1

ERK1

P21 RAS

PI 3 KINASE P85 ALPHA

RUNX1

AKT3

BAD

BCL X

BCR

C ABL

CBL C

CDK6

ERK2

GAB2

GRB2

IKK BETA

KRAS

NF-KB P65

NFKB1

P21

P38

PI 3 KINASE P55 GAMMA

PIK3R5

TGF BETA 2

TGF BETA RECEPTOR I

TGF BETA RECEPTOR II

A RAF

AKT2

B RAF

C-MYC

CBL

CBLB

CDK4

CRKL

CYCLIN D1

E2F1

E2F2

E2F3

HDAC1

HDAC2

IKB ALPHA

IKK ALPHA

MEK1

MEK2

NRAS

P27 KIP 1

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

PI 3 KINASE CATALYTIC SUBUNIT GAMMA

PI 3 KINASE P85 BETA

PIK3CB

PIK3CD

RAF1

RB

SHP2

SMAD4

SOS1

STAT5A

STAT5B

TGF BETA 1

TGF BETA 3

Plasmids

Myc-DDK

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-Myc-DDK

No

LentiORF

Druggable Genome

Transcription Factors

Protein Kinase

ES Cell Differentiation/IPS

Transmembrane

Stem cell - Pluripotency

Stem cell relevant signaling - JAK/STAT signaling pathway

Embryonic stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Stem cell relevant signaling - Wnt Signaling pathway

Cancer stem cells

Secreted Protein

Stem cell relevant signaling - DSL/Notch pathway

Adult stem cells

Induced pluripotent stem cells

Phosphatase

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Neuroactive ligand-receptor interaction

Cytokine-cytokine receptor interaction

Regulation of actin cytoskeleton

Focal adhesion

Chemokine signaling pathway

Calcium signaling pathway

Neurotrophin signaling pathway

Wnt signaling pathway

Jak-STAT signaling pathway

Progesterone-mediated oocyte maturation

Insulin signaling pathway

Purine metabolism

T cell receptor signaling pathway

Endocytosis

Cell cycle

ErbB signaling pathway

Natural killer cell mediated cytotoxicity

Axon guidance

Apoptosis

Prostate cancer

Oocyte meiosis

Toll-like receptor signaling pathway

Hematopoietic cell lineage

Adherens junction

Ubiquitin mediated proteolysis

Colorectal cancer

Alzheimer's disease

Leukocyte transendothelial migration

GnRH signaling pathway

Melanogenesis

Pancreatic cancer

Vascular smooth muscle contraction

Cell adhesion molecules (CAMs)

Gap junction

VEGF signaling pathway

Huntington's disease

Dilated cardiomyopathy

Olfactory transduction

B cell receptor signaling pathway

Chronic myeloid leukemia

Renal cell carcinoma

Melanoma

Small cell lung cancer

Tight junction

TGF-beta signaling pathway

p53 signaling pathway

Fc gamma R-mediated phagocytosis

Hypertrophic cardiomyopathy (HCM)

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Lysosome

Fc epsilon RI signaling pathway

Glioma

Acute myeloid leukemia

NOD-like receptor signaling pathway

Adipocytokine signaling pathway

Complement and coagulation cascades

Long-term potentiation

Phosphatidylinositol signaling system

Long-term depression

Endometrial cancer

Amyotrophic lateral sclerosis (ALS)

RIG-I-like receptor signaling pathway

PPAR signaling pathway

Non-small cell lung cancer

ECM-receptor interaction

Bladder cancer

Basal cell carcinoma

Glycolysis / Gluconeogenesis

Epithelial cell signaling in Helicobacter pylori infection

Inositol phosphate metabolism

Viral myocarditis

mTOR signaling pathway

Type II diabetes mellitus

Drug metabolism - cytochrome P450

Thyroid cancer

Cardiac muscle contraction

Hedgehog signaling pathway

Pathogenic Escherichia coli infection

Metabolism of xenobiotics by cytochrome P450

Glycerophospholipid metabolism

ABC transporters

Valine

Cytosolic DNA-sensing pathway

Antigen processing and presentation

Pyrimidine metabolism

Parkinson's disease

Retinol metabolism

Arginine and proline metabolism

Primary immunodeficiency

Arachidonic acid metabolism

Glycerolipid metabolism

Base excision repair

Drug metabolism - other enzymes

Tyrosine metabolism

leucine and isoleucine degradation

Fatty acid metabolism

Autoimmune thyroid disease

Lysine degradation

Sphingolipid metabolism

Systemic lupus erythematosus

Taste transduction

Fructose and mannose metabolism

Cysteine and methionine metabolism

Prion diseases

Nucleotide excision repair

Glutathione metabolism

SNARE interactions in vesicular transport

Starch and sucrose metabolism

Vibrio cholerae infection

Amino sugar and nucleotide sugar metabolism

Galactose metabolism

Pyruvate metabolism

Tryptophan metabolism

Butanoate metabolism

Type I diabetes mellitus

Alanine

Notch signaling pathway

aspartate and glutamate metabolism

Proteasome

Homologous recombination

Linoleic acid metabolism

Histidine metabolism

Pentose phosphate pathway

Aminoacyl-tRNA biosynthesis

Androgen and estrogen metabolism

Ether lipid metabolism

Nitrogen metabolism

Oxidative phosphorylation

Maturity onset diabetes of the young

Propanoate metabolism

Renin-angiotensin system

Citrate cycle (TCA cycle)

Regulation of autophagy

Allograft rejection

Mismatch repair

Glycosaminoglycan degradation

Porphyrin and chlorophyll metabolism

Riboflavin metabolism

Phenylalanine metabolism

Spliceosome

Dorso-ventral axis formation

Pantothenate and CoA biosynthesis

Ribosome

Selenoamino acid metabolism

Non-homologous end-joining

beta-Alanine metabolism

leucine and isoleucine biosynthesis

Graft-versus-host disease

Other glycan degradation

DNA replication

Glycine

N-Glycan biosynthesis

Steroid biosynthesis

serine and threonine metabolism

C21-Steroid hormone metabolism

Circadian rhythm - mammal

Primary bile acid biosynthesis

alpha-Linolenic acid metabolism

Asthma

Folate biosynthesis

Terpenoid backbone biosynthesis

Synthesis and degradation of ketone bodies

Basal transcription factors

RNA degradation

Nicotinate and nicotinamide metabolism

Pentose and glucuronate interconversions

Ascorbate and aldarate metabolism

Glyoxylate and dicarboxylate metabolism

Biosynthesis of unsaturated fatty acids

Glycosphingolipid biosynthesis - globo series

Limonene and pinene degradation

One carbon pool by folate

Thiamine metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Ubiquinone and other terpenoid-quinone biosynthesis

Caffeine metabolism

Glycosphingolipid biosynthesis - ganglio series

Sulfur metabolism

Fatty acid elongation in mitochondria

Heparan sulfate biosynthesis

Protein export

Taurine and hypotaurine metabolism

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Methane metabolism

Phenylalanine

tyrosine and tryptophan biosynthesis

RNA polymerase

Chondroitin sulfate biosynthesis

Fatty acid biosynthesis

O-Glycan biosynthesis

Vitamin B6 metabolism

Biotin metabolism

D-Arginine and D-ornithine metabolism

D-Glutamine and D-glutamate metabolism

Keratan sulfate biosynthesis

Lysine biosynthesis

Puromycin

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