Expression Plasmids

cDNA Clones

Expression Plasmids

Human

EVI1

IKK GAMMA

P16INK4A

P21 RAS

RUNX1

ACTIVIN A RECEPTOR TYPE IC

AKT1

AKT3

BCL X

C ABL

ERK2

GAB2

GRB2

KRAS

NFKB1

P21

P53

PI 3 KINASE P55 GAMMA

PI 3 KINASE P85 ALPHA

PIK3R5

TGF BETA 2

TGF BETA RECEPTOR I

TGF BETA RECEPTOR II

A RAF

ACTIVIN A RECEPTOR TYPE IB

AKT2

B RAF

BAD

BCR

C-MYC

CBL

CBL C

CBLB

CDK4

CDK6

CRKL

CYCLIN D1

E2F1

E2F3

ERK1

HDAC1

HDAC2

IKB ALPHA

IKK ALPHA

IKK BETA

MDM2

MEK1

MEK2

NF-KB P65

NRAS

P27 KIP 1

P38

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

PI 3 KINASE CATALYTIC SUBUNIT GAMMA

PI 3 KINASE P85 BETA

PIK3CB

PIK3CD

RAF1

SHC

SHP2

SMAD3

SMAD4

SOS1

STAT5A

STAT5B

TGF BETA 1

TGF BETA 3

Plasmids

mGFP

pLenti-C-mGFP-P2A-Puro

pLenti-C-mGFP

No

LentiORF

Druggable Genome

Transcription Factors

Protein Kinase

ES Cell Differentiation/IPS

Transmembrane

Stem cell - Pluripotency

Stem cell relevant signaling - JAK/STAT signaling pathway

Secreted Protein

Stem cell relevant signaling - DSL/Notch pathway

Stem cell relevant signaling - Wnt Signaling pathway

Embryonic stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Adult stem cells

Cancer stem cells

Induced pluripotent stem cells

Phosphatase

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Chemokine signaling pathway

Focal adhesion

Regulation of actin cytoskeleton

Neurotrophin signaling pathway

Jak-STAT signaling pathway

Calcium signaling pathway

Wnt signaling pathway

Natural killer cell mediated cytotoxicity

T cell receptor signaling pathway

Insulin signaling pathway

Toll-like receptor signaling pathway

ErbB signaling pathway

Progesterone-mediated oocyte maturation

Endocytosis

Apoptosis

Colorectal cancer

Prostate cancer

Axon guidance

Pancreatic cancer

Oocyte meiosis

Cell cycle

GnRH signaling pathway

Leukocyte transendothelial migration

Chronic myeloid leukemia

B cell receptor signaling pathway

Melanogenesis

VEGF signaling pathway

Alzheimer's disease

Gap junction

Fc epsilon RI signaling pathway

Small cell lung cancer

Cell adhesion molecules (CAMs)

Melanoma

Renal cell carcinoma

Vascular smooth muscle contraction

Adherens junction

TGF-beta signaling pathway

Ubiquitin mediated proteolysis

Hematopoietic cell lineage

Glioma

NOD-like receptor signaling pathway

Adipocytokine signaling pathway

Tight junction

Acute myeloid leukemia

Fc gamma R-mediated phagocytosis

Non-small cell lung cancer

Long-term potentiation

Purine metabolism

RIG-I-like receptor signaling pathway

Huntington's disease

p53 signaling pathway

Dilated cardiomyopathy

Endometrial cancer

Amyotrophic lateral sclerosis (ALS)

Long-term depression

Hypertrophic cardiomyopathy (HCM)

Bladder cancer

Lysosome

Epithelial cell signaling in Helicobacter pylori infection

Type II diabetes mellitus

Complement and coagulation cascades

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

mTOR signaling pathway

Hedgehog signaling pathway

ECM-receptor interaction

Phosphatidylinositol signaling system

Basal cell carcinoma

Glycolysis / Gluconeogenesis

Pathogenic Escherichia coli infection

Cytosolic DNA-sensing pathway

PPAR signaling pathway

Thyroid cancer

Parkinson's disease

Viral myocarditis

Antigen processing and presentation

Primary immunodeficiency

Arginine and proline metabolism

Metabolism of xenobiotics by cytochrome P450

Retinol metabolism

Olfactory transduction

Autoimmune thyroid disease

Nucleotide excision repair

ABC transporters

Drug metabolism - cytochrome P450

Lysine degradation

Cardiac muscle contraction

Valine

Vibrio cholerae infection

Arachidonic acid metabolism

Inositol phosphate metabolism

Prion diseases

Regulation of autophagy

Tyrosine metabolism

Drug metabolism - other enzymes

leucine and isoleucine degradation

Base excision repair

Maturity onset diabetes of the young

Notch signaling pathway

Pyruvate metabolism

Systemic lupus erythematosus

Taste transduction

Fructose and mannose metabolism

Pyrimidine metabolism

Starch and sucrose metabolism

Tryptophan metabolism

Type I diabetes mellitus

Galactose metabolism

Glycerophospholipid metabolism

Sphingolipid metabolism

Amino sugar and nucleotide sugar metabolism

Cysteine and methionine metabolism

Androgen and estrogen metabolism

Glutathione metabolism

Allograft rejection

Citrate cycle (TCA cycle)

Fatty acid metabolism

Glycerolipid metabolism

Homologous recombination

Dorso-ventral axis formation

Linoleic acid metabolism

Renin-angiotensin system

Propanoate metabolism

Spliceosome

Mismatch repair

Nitrogen metabolism

Oxidative phosphorylation

Alanine

Ether lipid metabolism

Graft-versus-host disease

Histidine metabolism

Pentose phosphate pathway

Phenylalanine metabolism

Proteasome

SNARE interactions in vesicular transport

aspartate and glutamate metabolism

Butanoate metabolism

Circadian rhythm - mammal

Glycosaminoglycan degradation

Glycine

Non-homologous end-joining

Porphyrin and chlorophyll metabolism

serine and threonine metabolism

DNA replication

Ribosome

C21-Steroid hormone metabolism

Other glycan degradation

Riboflavin metabolism

beta-Alanine metabolism

Asthma

Primary bile acid biosynthesis

Steroid biosynthesis

Aminoacyl-tRNA biosynthesis

Folate biosynthesis

N-Glycan biosynthesis

Basal transcription factors

Glycosphingolipid biosynthesis - globo series

Terpenoid backbone biosynthesis

alpha-Linolenic acid metabolism

Ascorbate and aldarate metabolism

Glyoxylate and dicarboxylate metabolism

Nicotinate and nicotinamide metabolism

Pantothenate and CoA biosynthesis

Pentose and glucuronate interconversions

leucine and isoleucine biosynthesis

Glycosphingolipid biosynthesis - lacto and neolacto series

Limonene and pinene degradation

One carbon pool by folate

RNA degradation

Selenoamino acid metabolism

Biosynthesis of unsaturated fatty acids

Glycosphingolipid biosynthesis - ganglio series

Methane metabolism

Thiamine metabolism

Caffeine metabolism

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Protein export

Taurine and hypotaurine metabolism

Fatty acid elongation in mitochondria

Heparan sulfate biosynthesis

O-Glycan biosynthesis

Synthesis and degradation of ketone bodies

Ubiquinone and other terpenoid-quinone biosynthesis

Vitamin B6 metabolism

D-Arginine and D-ornithine metabolism

D-Glutamine and D-glutamate metabolism

Keratan sulfate biosynthesis

Phenylalanine

Sulfur metabolism

tyrosine and tryptophan biosynthesis

None

1

Yes

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