Expression Plasmids

cDNA Clones

Expression Plasmids

Human

ASAH1

GBA

SPHK1

ACID SPHINGOMYELINASE

ARSA

DEGS1

GALACTOSIDASE ALPHA

GALACTOSYLCERAMIDASE

GLB1

NEURAMINIDASE

PHOSPHATIDIC ACID PHOSPHATASE TYPE 2B

SGPL1

SPHINGOMYELIN SYNTHASE 2

SPHINGOSINE 1 PHOSPHATE PHOSPHATASE 1

SPHK2

SPTLC1

Plasmids

Myc-DDK

mGFP

pLenti-C-Myc-DDK

pLenti-C-mGFP

No

LentiORF

Druggable Genome

Transmembrane

Phosphatase

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Focal adhesion

Chemokine signaling pathway

Regulation of actin cytoskeleton

Neurotrophin signaling pathway

Calcium signaling pathway

Jak-STAT signaling pathway

Wnt signaling pathway

Natural killer cell mediated cytotoxicity

T cell receptor signaling pathway

Insulin signaling pathway

Toll-like receptor signaling pathway

ErbB signaling pathway

Progesterone-mediated oocyte maturation

Endocytosis

Prostate cancer

Colorectal cancer

Apoptosis

Axon guidance

Pancreatic cancer

Oocyte meiosis

GnRH signaling pathway

Cell cycle

Leukocyte transendothelial migration

Chronic myeloid leukemia

Melanogenesis

B cell receptor signaling pathway

Alzheimer's disease

VEGF signaling pathway

Small cell lung cancer

Gap junction

Vascular smooth muscle contraction

Cell adhesion molecules (CAMs)

Fc epsilon RI signaling pathway

Renal cell carcinoma

Adherens junction

Melanoma

TGF-beta signaling pathway

Ubiquitin mediated proteolysis

Hematopoietic cell lineage

Glioma

NOD-like receptor signaling pathway

Adipocytokine signaling pathway

Tight junction

Acute myeloid leukemia

Fc gamma R-mediated phagocytosis

Long-term potentiation

Non-small cell lung cancer

Huntington's disease

Purine metabolism

RIG-I-like receptor signaling pathway

Dilated cardiomyopathy

p53 signaling pathway

Endometrial cancer

Hypertrophic cardiomyopathy (HCM)

Long-term depression

Amyotrophic lateral sclerosis (ALS)

Type II diabetes mellitus

Bladder cancer

Lysosome

Epithelial cell signaling in Helicobacter pylori infection

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Complement and coagulation cascades

mTOR signaling pathway

ECM-receptor interaction

Hedgehog signaling pathway

Phosphatidylinositol signaling system

Basal cell carcinoma

Glycolysis / Gluconeogenesis

Pathogenic Escherichia coli infection

Cytosolic DNA-sensing pathway

PPAR signaling pathway

Thyroid cancer

Parkinson's disease

Viral myocarditis

Antigen processing and presentation

Primary immunodeficiency

Arginine and proline metabolism

Metabolism of xenobiotics by cytochrome P450

Retinol metabolism

Olfactory transduction

ABC transporters

Nucleotide excision repair

Autoimmune thyroid disease

Cardiac muscle contraction

Lysine degradation

Drug metabolism - cytochrome P450

Vibrio cholerae infection

Valine

Inositol phosphate metabolism

Arachidonic acid metabolism

Notch signaling pathway

Prion diseases

Regulation of autophagy

Tyrosine metabolism

Pyruvate metabolism

Base excision repair

Drug metabolism - other enzymes

Pyrimidine metabolism

Taste transduction

leucine and isoleucine degradation

Systemic lupus erythematosus

Maturity onset diabetes of the young

Starch and sucrose metabolism

Tryptophan metabolism

Fructose and mannose metabolism

Type I diabetes mellitus

Galactose metabolism

Glycerophospholipid metabolism

Sphingolipid metabolism

Amino sugar and nucleotide sugar metabolism

Cysteine and methionine metabolism

Androgen and estrogen metabolism

Glutathione metabolism

Fatty acid metabolism

Glycerolipid metabolism

Allograft rejection

Citrate cycle (TCA cycle)

Dorso-ventral axis formation

Homologous recombination

Propanoate metabolism

Linoleic acid metabolism

Renin-angiotensin system

Spliceosome

Mismatch repair

Nitrogen metabolism

Oxidative phosphorylation

Histidine metabolism

Alanine

Ether lipid metabolism

Graft-versus-host disease

Pentose phosphate pathway

Phenylalanine metabolism

Proteasome

SNARE interactions in vesicular transport

aspartate and glutamate metabolism

Butanoate metabolism

Circadian rhythm - mammal

Glycosaminoglycan degradation

Glycine

Non-homologous end-joining

Porphyrin and chlorophyll metabolism

serine and threonine metabolism

DNA replication

Ribosome

beta-Alanine metabolism

C21-Steroid hormone metabolism

Other glycan degradation

Riboflavin metabolism

Asthma

Primary bile acid biosynthesis

Steroid biosynthesis

Aminoacyl-tRNA biosynthesis

Folate biosynthesis

N-Glycan biosynthesis

Basal transcription factors

Glycosphingolipid biosynthesis - globo series

Terpenoid backbone biosynthesis

alpha-Linolenic acid metabolism

Ascorbate and aldarate metabolism

Glyoxylate and dicarboxylate metabolism

Nicotinate and nicotinamide metabolism

Pantothenate and CoA biosynthesis

Pentose and glucuronate interconversions

leucine and isoleucine biosynthesis

Limonene and pinene degradation

Glycosphingolipid biosynthesis - lacto and neolacto series

One carbon pool by folate

RNA degradation

Selenoamino acid metabolism

Biosynthesis of unsaturated fatty acids

Glycosphingolipid biosynthesis - ganglio series

Methane metabolism

Thiamine metabolism

Caffeine metabolism

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Protein export

Taurine and hypotaurine metabolism

Fatty acid elongation in mitochondria

Heparan sulfate biosynthesis

O-Glycan biosynthesis

Synthesis and degradation of ketone bodies

Ubiquinone and other terpenoid-quinone biosynthesis

Vitamin B6 metabolism

Fatty acid biosynthesis

D-Arginine and D-ornithine metabolism

D-Glutamine and D-glutamate metabolism

Keratan sulfate biosynthesis

Phenylalanine

Sulfur metabolism

tyrosine and tryptophan biosynthesis

Puromycin

None

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