Expression Plasmids

cDNA Clones

Expression Plasmids

Human

PTCH1

CSNK1G3

BETA TRCP2

BMP4

GLI1

PRKACB

BETA TRCP

CASEIN KINASE 1 ALPHA

CASEIN KINASE 1 DELTA

CK1 EPSILON

GSK3 BETA

PRKACA

PTCH2

RAB23

SUPPRESSOR OF FUSED

BMP2

BMP5

BMP6

BMP7

BMP8B

CSNK1A1L

CSNK1G1

CSNK1G2

DHH

GLI2

GLI3

IHH

PRKACG

PRKX

SMOOTHENED

SONIC HEDGEHOG

STK36

WNT1

WNT10B

WNT3

WNT3A

WNT4

WNT5A

WNT7A

ZIC2

Plasmids

Myc-DDK

mGFP

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP-P2A-Puro

No

LentiORF

Druggable Genome

ES Cell Differentiation/IPS

Secreted Protein

Transmembrane

Protein Kinase

Cancer stem cells

Adult stem cells

Embryonic stem cells

Induced pluripotent stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Stem cell relevant signaling - Wnt Signaling pathway

Transcription Factors

Stem cell relevant signaling - DSL/Notch pathway

Protease

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Neuroactive ligand-receptor interaction

Cytokine-cytokine receptor interaction

Regulation of actin cytoskeleton

Focal adhesion

Chemokine signaling pathway

Calcium signaling pathway

Neurotrophin signaling pathway

Wnt signaling pathway

Jak-STAT signaling pathway

Progesterone-mediated oocyte maturation

Insulin signaling pathway

T cell receptor signaling pathway

Purine metabolism

Endocytosis

Cell cycle

ErbB signaling pathway

Natural killer cell mediated cytotoxicity

Axon guidance

Apoptosis

Prostate cancer

Oocyte meiosis

Toll-like receptor signaling pathway

Hematopoietic cell lineage

Adherens junction

Ubiquitin mediated proteolysis

Colorectal cancer

Alzheimer's disease

Leukocyte transendothelial migration

GnRH signaling pathway

Pancreatic cancer

Melanogenesis

Vascular smooth muscle contraction

Cell adhesion molecules (CAMs)

VEGF signaling pathway

Gap junction

Huntington's disease

Dilated cardiomyopathy

Olfactory transduction

B cell receptor signaling pathway

Chronic myeloid leukemia

Renal cell carcinoma

Melanoma

Small cell lung cancer

Tight junction

TGF-beta signaling pathway

p53 signaling pathway

Fc gamma R-mediated phagocytosis

Hypertrophic cardiomyopathy (HCM)

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Lysosome

Fc epsilon RI signaling pathway

Glioma

Acute myeloid leukemia

NOD-like receptor signaling pathway

Adipocytokine signaling pathway

Complement and coagulation cascades

Long-term potentiation

Phosphatidylinositol signaling system

Long-term depression

Endometrial cancer

Amyotrophic lateral sclerosis (ALS)

RIG-I-like receptor signaling pathway

PPAR signaling pathway

Non-small cell lung cancer

ECM-receptor interaction

Bladder cancer

Basal cell carcinoma

Glycolysis / Gluconeogenesis

Epithelial cell signaling in Helicobacter pylori infection

Inositol phosphate metabolism

Viral myocarditis

mTOR signaling pathway

Type II diabetes mellitus

Drug metabolism - cytochrome P450

Thyroid cancer

Cardiac muscle contraction

Hedgehog signaling pathway

Pathogenic Escherichia coli infection

Metabolism of xenobiotics by cytochrome P450

Glycerophospholipid metabolism

ABC transporters

Valine

Cytosolic DNA-sensing pathway

Antigen processing and presentation

Parkinson's disease

Pyrimidine metabolism

Retinol metabolism

Arginine and proline metabolism

Primary immunodeficiency

Arachidonic acid metabolism

Glycerolipid metabolism

Drug metabolism - other enzymes

Tyrosine metabolism

Base excision repair

leucine and isoleucine degradation

Fatty acid metabolism

Autoimmune thyroid disease

Sphingolipid metabolism

Systemic lupus erythematosus

Taste transduction

Lysine degradation

Fructose and mannose metabolism

Cysteine and methionine metabolism

Prion diseases

Nucleotide excision repair

Glutathione metabolism

SNARE interactions in vesicular transport

Starch and sucrose metabolism

Vibrio cholerae infection

Amino sugar and nucleotide sugar metabolism

Galactose metabolism

Pyruvate metabolism

Tryptophan metabolism

Butanoate metabolism

Type I diabetes mellitus

Alanine

Notch signaling pathway

aspartate and glutamate metabolism

Proteasome

Homologous recombination

Linoleic acid metabolism

Pentose phosphate pathway

Histidine metabolism

Aminoacyl-tRNA biosynthesis

Androgen and estrogen metabolism

Ether lipid metabolism

Nitrogen metabolism

Oxidative phosphorylation

Maturity onset diabetes of the young

Renin-angiotensin system

Propanoate metabolism

Citrate cycle (TCA cycle)

Regulation of autophagy

Allograft rejection

Mismatch repair

Glycosaminoglycan degradation

Porphyrin and chlorophyll metabolism

Riboflavin metabolism

Phenylalanine metabolism

Spliceosome

Dorso-ventral axis formation

Ribosome

Selenoamino acid metabolism

Pantothenate and CoA biosynthesis

Non-homologous end-joining

leucine and isoleucine biosynthesis

beta-Alanine metabolism

Graft-versus-host disease

Other glycan degradation

DNA replication

Glycine

N-Glycan biosynthesis

Steroid biosynthesis

serine and threonine metabolism

C21-Steroid hormone metabolism

Circadian rhythm - mammal

Primary bile acid biosynthesis

alpha-Linolenic acid metabolism

Asthma

Folate biosynthesis

Terpenoid backbone biosynthesis

Synthesis and degradation of ketone bodies

Basal transcription factors

RNA degradation

Pentose and glucuronate interconversions

Nicotinate and nicotinamide metabolism

Glyoxylate and dicarboxylate metabolism

Ascorbate and aldarate metabolism

Biosynthesis of unsaturated fatty acids

Glycosphingolipid biosynthesis - globo series

One carbon pool by folate

Thiamine metabolism

Limonene and pinene degradation

Glycosphingolipid biosynthesis - lacto and neolacto series

Ubiquinone and other terpenoid-quinone biosynthesis

Caffeine metabolism

Glycosphingolipid biosynthesis - ganglio series

Sulfur metabolism

Fatty acid elongation in mitochondria

Heparan sulfate biosynthesis

Protein export

Taurine and hypotaurine metabolism

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Methane metabolism

Phenylalanine

tyrosine and tryptophan biosynthesis

RNA polymerase

Chondroitin sulfate biosynthesis

Fatty acid biosynthesis

O-Glycan biosynthesis

Vitamin B6 metabolism

Biotin metabolism

D-Arginine and D-ornithine metabolism

D-Glutamine and D-glutamate metabolism

Keratan sulfate biosynthesis

Lysine biosynthesis

Neomycin

None

Puromycin

1

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