Expression Plasmids

cDNA Clones

Expression Plasmids

Human

P53

DP2

MDM2

SMAD3

E2F5

SMAD2

C ABL

CYCLIN E1

MCM4

MCM7

P107

14 3 3 ETA

C-MYC

CDK7

CYCLIN H

DP1

E2F1

E2F2

E2F3

E2F4

HDAC1

HDAC2

MCM2

MCM3

MCM5

MCM6

MIZ1

ORC2

RB

RB2 P130

SECURIN

SMAD4

TGF BETA 1

Plasmids

Myc-DDK

mGFP

pLenti-C-mGFP-P2A-Puro

No

LentiORF

Druggable Genome

Transcription Factors

Stem cell - Pluripotency

Protein Kinase

Phosphatase

Stem cell relevant signaling - JAK/STAT signaling pathway

ES Cell Differentiation/IPS

Embryonic stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Cancer stem cells

Secreted Protein

Stem cell relevant signaling - DSL/Notch pathway

Transmembrane

Stem cell relevant signaling - Wnt Signaling pathway

Adult stem cells

Induced pluripotent stem cells

Pathways in cancer

Wnt signaling pathway

MAPK signaling pathway

Acute myeloid leukemia

Prostate cancer

Cell cycle

Huntington's disease

Chronic myeloid leukemia

TGF-beta signaling pathway

Metabolic pathways

Thyroid cancer

Basal transcription factors

T cell receptor signaling pathway

Colorectal cancer

Neurotrophin signaling pathway

Ubiquitin mediated proteolysis

B cell receptor signaling pathway

Small cell lung cancer

Pancreatic cancer

Toll-like receptor signaling pathway

Melanogenesis

Purine metabolism

Pyrimidine metabolism

Basal cell carcinoma

Cytosolic DNA-sensing pathway

Endometrial cancer

Adherens junction

Adipocytokine signaling pathway

RNA polymerase

ErbB signaling pathway

Apoptosis

Spliceosome

Axon guidance

Maturity onset diabetes of the young

Natural killer cell mediated cytotoxicity

Chemokine signaling pathway

Melanoma

VEGF signaling pathway

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Jak-STAT signaling pathway

RIG-I-like receptor signaling pathway

Neuroactive ligand-receptor interaction

Endocytosis

Renal cell carcinoma

p53 signaling pathway

Bladder cancer

Non-small cell lung cancer

Oocyte meiosis

RNA degradation

Amyotrophic lateral sclerosis (ALS)

Antigen processing and presentation

Nucleotide excision repair

PPAR signaling pathway

Tight junction

Glioma

Insulin signaling pathway

Notch signaling pathway

NOD-like receptor signaling pathway

Viral myocarditis

Calcium signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

Circadian rhythm - mammal

Systemic lupus erythematosus

DNA replication

Focal adhesion

Lysine degradation

Primary immunodeficiency

Alzheimer's disease

Fc gamma R-mediated phagocytosis

GnRH signaling pathway

Long-term depression

Dorso-ventral axis formation

Pathogenic Escherichia coli infection

Allograft rejection

Base excision repair

Graft-versus-host disease

Hedgehog signaling pathway

Leukocyte transendothelial migration

Long-term potentiation

Ribosome

Type I diabetes mellitus

Autoimmune thyroid disease

Cell adhesion molecules (CAMs)

Cysteine and methionine metabolism

Cytokine-cytokine receptor interaction

Fc epsilon RI signaling pathway

Homologous recombination

Regulation of actin cytoskeleton

Type II diabetes mellitus

Valine

Aminoacyl-tRNA biosynthesis

Ether lipid metabolism

SNARE interactions in vesicular transport

leucine and isoleucine biosynthesis

mTOR signaling pathway

Dilated cardiomyopathy

Glycerolipid metabolism

Glycine

Glyoxylate and dicarboxylate metabolism

Hypertrophic cardiomyopathy (HCM)

Prion diseases

serine and threonine metabolism

Asthma

Glycolysis / Gluconeogenesis

Hematopoietic cell lineage

Mismatch repair

Nicotinate and nicotinamide metabolism

Non-homologous end-joining

Progesterone-mediated oocyte maturation

Proteasome

Vascular smooth muscle contraction

leucine and isoleucine degradation

Puromycin

None

1

Yes

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