Expression Plasmids

cDNA Clones

Expression Plasmids

Human

PORCN

FRIZZLED 6

VANGL1

PRESENILIN 1

WNT16

FRIZZLED 10

FRIZZLED 2

FRIZZLED 4

FRIZZLED 5

FRIZZLED 7

FRIZZLED 8

FRIZZLED 9

FRIZZLED HOMOLOG 1

FZD3

LRP5

LRP6

SFRP1

VANGL2

WNT1

WNT10A

WNT11

WNT3

WNT4

WNT6

WNT7A

WNT7B

WNT9A

WNT9B

Plasmids

Myc-DDK

mGFP

pLenti-C-mGFP-P2A-Puro

No

LentiORF

Druggable Genome

Transcription Factors

Protein Kinase

ES Cell Differentiation/IPS

Transmembrane

Secreted Protein

Phosphatase

Stem cell relevant signaling - Wnt Signaling pathway

Cancer stem cells

Adult stem cells

Stem cell - Pluripotency

GPCR

Stem cell relevant signaling - JAK/STAT signaling pathway

Embryonic stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Nuclear Hormone Receptor

Induced pluripotent stem cells

Protease

Stem cell relevant signaling - DSL/Notch pathway

Metabolic pathways

Neuroactive ligand-receptor interaction

Olfactory transduction

Cytokine-cytokine receptor interaction

Cell adhesion molecules (CAMs)

Calcium signaling pathway

Hematopoietic cell lineage

Pathways in cancer

MAPK signaling pathway

Regulation of actin cytoskeleton

Alzheimer's disease

Jak-STAT signaling pathway

Natural killer cell mediated cytotoxicity

Dilated cardiomyopathy

Endocytosis

Antigen processing and presentation

Hypertrophic cardiomyopathy (HCM)

Huntington's disease

Lysosome

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

N-Glycan biosynthesis

ECM-receptor interaction

Axon guidance

Oxidative phosphorylation

Leukocyte transendothelial migration

Chemokine signaling pathway

ABC transporters

Vascular smooth muscle contraction

Viral myocarditis

Focal adhesion

Parkinson's disease

Drug metabolism - cytochrome P450

Adherens junction

SNARE interactions in vesicular transport

Retinol metabolism

Cardiac muscle contraction

Melanogenesis

ErbB signaling pathway

Purine metabolism

Systemic lupus erythematosus

Glycerophospholipid metabolism

PPAR signaling pathway

Tight junction

Adipocytokine signaling pathway

Colorectal cancer

Glycosphingolipid biosynthesis - lacto and neolacto series

Graft-versus-host disease

Metabolism of xenobiotics by cytochrome P450

Apoptosis

Autoimmune thyroid disease

Neurotrophin signaling pathway

Prostate cancer

Sphingolipid metabolism

O-Glycan biosynthesis

Wnt signaling pathway

Basal cell carcinoma

Gap junction

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Taste transduction

Drug metabolism - other enzymes

Vibrio cholerae infection

Allograft rejection

Amyotrophic lateral sclerosis (ALS)

Androgen and estrogen metabolism

Melanoma

Type I diabetes mellitus

Arachidonic acid metabolism

Epithelial cell signaling in Helicobacter pylori infection

Toll-like receptor signaling pathway

Keratan sulfate biosynthesis

Starch and sucrose metabolism

Ether lipid metabolism

Fc gamma R-mediated phagocytosis

Porphyrin and chlorophyll metabolism

Primary immunodeficiency

Heparan sulfate biosynthesis

T cell receptor signaling pathway

TGF-beta signaling pathway

Pancreatic cancer

Complement and coagulation cascades

GnRH signaling pathway

Fatty acid metabolism

Hedgehog signaling pathway

Long-term depression

Asthma

Chondroitin sulfate biosynthesis

Pyrimidine metabolism

B cell receptor signaling pathway

Glycerolipid metabolism

Ascorbate and aldarate metabolism

Long-term potentiation

Glycosphingolipid biosynthesis - globo series

Linoleic acid metabolism

Pentose and glucuronate interconversions

p53 signaling pathway

Glutathione metabolism

Notch signaling pathway

Renin-angiotensin system

Tyrosine metabolism

Fc epsilon RI signaling pathway

Glycosphingolipid biosynthesis - ganglio series

Chronic myeloid leukemia

Small cell lung cancer

Steroid biosynthesis

Prion diseases

Bladder cancer

Progesterone-mediated oocyte maturation

Biosynthesis of unsaturated fatty acids

Glioma

Renal cell carcinoma

Nicotinate and nicotinamide metabolism

Non-small cell lung cancer

Oocyte meiosis

Pathogenic Escherichia coli infection

Riboflavin metabolism

Endometrial cancer

Glycosaminoglycan degradation

Insulin signaling pathway

Ubiquitin mediated proteolysis

Cytosolic DNA-sensing pathway

Galactose metabolism

Primary bile acid biosynthesis

VEGF signaling pathway

alpha-Linolenic acid metabolism

Cyanoamino acid metabolism

Phosphatidylinositol signaling system

RIG-I-like receptor signaling pathway

Selenoamino acid metabolism

Taurine and hypotaurine metabolism

Type II diabetes mellitus

Caffeine metabolism

Inositol phosphate metabolism

O-Mannosyl glycan biosynthesis

Phenylalanine metabolism

Thyroid cancer

Tryptophan metabolism

C21-Steroid hormone metabolism

Glycine

Glycolysis / Gluconeogenesis

Nitrogen metabolism

beta-Alanine metabolism

serine and threonine metabolism

Amino sugar and nucleotide sugar metabolism

Citrate cycle (TCA cycle)

Dorso-ventral axis formation

Limonene and pinene degradation

NOD-like receptor signaling pathway

Sulfur metabolism

Acute myeloid leukemia

Arginine and proline metabolism

Base excision repair

Cell cycle

Histidine metabolism

Lysine degradation

Propanoate metabolism

Protein export

Valine

leucine and isoleucine degradation

Butanoate metabolism

Fatty acid elongation in mitochondria

Other glycan degradation

Pantothenate and CoA biosynthesis

Pyruvate metabolism

Terpenoid backbone biosynthesis

Maturity onset diabetes of the young

Ubiquinone and other terpenoid-quinone biosynthesis

Puromycin

None

1

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