Expression Plasmids

cDNA Clones

Expression Plasmids

Human

APC11

P53

14-3-3 ZETA

DP2

ORC4L

ARTEMIS

CDK1

CYCLIN A1

CYCLIN D3

MDM2

P16INK4A

SMAD3

CDC14A

CDC14B

CDC25B

CDC45L

CDC7

CHK1

CHK2

E2F5

FZR1

MAD1

ORC3L

SA2

SMAD2

14-3-3 BETA

APC5

APC6

APC7

BUB3

C ABL

CDC25A

CDC25C

CDC27

CDK2

CDK6

CYCLIN B3

CYCLIN E1

GSK3 BETA

MAD2L2

MCM4

MCM7

MPS1

ORC1

ORC5L

P107

P15 INK4B

P18 INK4C

P19 INK4D

P21

PCNA

PKMYT1

SKP1

SKP2

TGF BETA 2

WEE1

14 3 3 ETA

14 3 3 GAMMA

14-3-3 EPSILON

14-3-3 SIGMA

14-3-3 THETA

ANAPC13

APC10

APC2

APC4

BUB1

BUBR1

C-MYC

CDC20

CDC23

CDC26

CDC6

CDK4

CDK7

CULLIN 1

CYCLIN A2

CYCLIN B1

CYCLIN B2

CYCLIN D1

CYCLIN D2

CYCLIN E2

CYCLIN H

DBF4

DP1

E2F1

E2F2

E2F3

E2F4

GADD45A

GADD45B

GADD45G

HDAC1

HDAC2

MAD2

MCM2

MCM3

MCM5

MCM6

MIZ1

ORC2

Plasmids

Myc-DDK

mGFP

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP-P2A-Puro

No

LentiORF

Druggable Genome

Transcription Factors

Stem cell - Pluripotency

Protein Kinase

Phosphatase

Stem cell relevant signaling - JAK/STAT signaling pathway

ES Cell Differentiation/IPS

Embryonic stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Cancer stem cells

Secreted Protein

Stem cell relevant signaling - DSL/Notch pathway

Transmembrane

Stem cell relevant signaling - Wnt Signaling pathway

Adult stem cells

Induced pluripotent stem cells

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Neuroactive ligand-receptor interaction

Cytokine-cytokine receptor interaction

Olfactory transduction

Regulation of actin cytoskeleton

Endocytosis

Focal adhesion

Chemokine signaling pathway

Calcium signaling pathway

Purine metabolism

Wnt signaling pathway

Huntington's disease

Neurotrophin signaling pathway

Alzheimer's disease

Ubiquitin mediated proteolysis

Jak-STAT signaling pathway

Axon guidance

Natural killer cell mediated cytotoxicity

Insulin signaling pathway

Progesterone-mediated oocyte maturation

Tight junction

Cell adhesion molecules (CAMs)

Cell cycle

Leukocyte transendothelial migration

Oocyte meiosis

Lysosome

T cell receptor signaling pathway

ErbB signaling pathway

Adherens junction

Fc gamma R-mediated phagocytosis

Prostate cancer

Toll-like receptor signaling pathway

Apoptosis

Hematopoietic cell lineage

Melanogenesis

Spliceosome

Vascular smooth muscle contraction

Oxidative phosphorylation

GnRH signaling pathway

Parkinson's disease

Dilated cardiomyopathy

Systemic lupus erythematosus

Colorectal cancer

Hypertrophic cardiomyopathy (HCM)

Pancreatic cancer

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

VEGF signaling pathway

Pyrimidine metabolism

Melanoma

B cell receptor signaling pathway

TGF-beta signaling pathway

Gap junction

PPAR signaling pathway

p53 signaling pathway

Chronic myeloid leukemia

Small cell lung cancer

Renal cell carcinoma

Antigen processing and presentation

Fc epsilon RI signaling pathway

Viral myocarditis

Acute myeloid leukemia

Complement and coagulation cascades

Glioma

RIG-I-like receptor signaling pathway

Adipocytokine signaling pathway

NOD-like receptor signaling pathway

Long-term potentiation

Phosphatidylinositol signaling system

Ribosome

Long-term depression

Glycerophospholipid metabolism

Epithelial cell signaling in Helicobacter pylori infection

Cardiac muscle contraction

Glycolysis / Gluconeogenesis

Endometrial cancer

Amyotrophic lateral sclerosis (ALS)

Drug metabolism - cytochrome P450

ECM-receptor interaction

Metabolism of xenobiotics by cytochrome P450

Pathogenic Escherichia coli infection

Non-small cell lung cancer

Vibrio cholerae infection

Basal cell carcinoma

mTOR signaling pathway

Bladder cancer

Cytosolic DNA-sensing pathway

Inositol phosphate metabolism

Drug metabolism - other enzymes

Retinol metabolism

Arginine and proline metabolism

Valine

Hedgehog signaling pathway

Arachidonic acid metabolism

Starch and sucrose metabolism

Glutathione metabolism

RNA degradation

Thyroid cancer

N-Glycan biosynthesis

Sphingolipid metabolism

Type II diabetes mellitus

Glycerolipid metabolism

Amino sugar and nucleotide sugar metabolism

Tyrosine metabolism

Fatty acid metabolism

leucine and isoleucine degradation

Autoimmune thyroid disease

Pyruvate metabolism

Lysine degradation

Cysteine and methionine metabolism

Primary immunodeficiency

Taste transduction

Proteasome

ABC transporters

Base excision repair

Nucleotide excision repair

Type I diabetes mellitus

Tryptophan metabolism

Notch signaling pathway

SNARE interactions in vesicular transport

Ether lipid metabolism

Alanine

aspartate and glutamate metabolism

Androgen and estrogen metabolism

Porphyrin and chlorophyll metabolism

Fructose and mannose metabolism

Graft-versus-host disease

Prion diseases

Aminoacyl-tRNA biosynthesis

Butanoate metabolism

Glycine

serine and threonine metabolism

Citrate cycle (TCA cycle)

Allograft rejection

Glycosphingolipid biosynthesis - lacto and neolacto series

Propanoate metabolism

Basal transcription factors

DNA replication

Galactose metabolism

Pentose phosphate pathway

Selenoamino acid metabolism

Nitrogen metabolism

Histidine metabolism

Glycosaminoglycan degradation

Homologous recombination

O-Glycan biosynthesis

Regulation of autophagy

Linoleic acid metabolism

Maturity onset diabetes of the young

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Nicotinate and nicotinamide metabolism

Dorso-ventral axis formation

Mismatch repair

Phenylalanine metabolism

RNA polymerase

Asthma

Pentose and glucuronate interconversions

Heparan sulfate biosynthesis

Primary bile acid biosynthesis

beta-Alanine metabolism

Biosynthesis of unsaturated fatty acids

Keratan sulfate biosynthesis

Ascorbate and aldarate metabolism

Pantothenate and CoA biosynthesis

One carbon pool by folate

Renin-angiotensin system

Riboflavin metabolism

Chondroitin sulfate biosynthesis

Other glycan degradation

Sulfur metabolism

alpha-Linolenic acid metabolism

Steroid biosynthesis

Glycosphingolipid biosynthesis - globo series

Terpenoid backbone biosynthesis

Non-homologous end-joining

leucine and isoleucine biosynthesis

Glyoxylate and dicarboxylate metabolism

Glycosphingolipid biosynthesis - ganglio series

Cyanoamino acid metabolism

Taurine and hypotaurine metabolism

Limonene and pinene degradation

C21-Steroid hormone metabolism

Circadian rhythm - mammal

Folate biosynthesis

Caffeine metabolism

Synthesis and degradation of ketone bodies

Protein export

Thiamine metabolism

Fatty acid elongation in mitochondria

Methane metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Lipoic acid metabolism

O-Mannosyl glycan biosynthesis

Fatty acid biosynthesis

Phenylalanine

Vitamin B6 metabolism

tyrosine and tryptophan biosynthesis

Lysine biosynthesis

D-Glutamine and D-glutamate metabolism

Biotin metabolism

D-Arginine and D-ornithine metabolism

Neomycin

Puromycin

None

1

Yes

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