Expression Plasmids

cDNA Clones

Expression Plasmids

Human

PTCH1

BETA TRCP2

BMP4

CSNK1G3

PRKACB

CASEIN KINASE 1 ALPHA

CASEIN KINASE 1 DELTA

CK1 EPSILON

GLI1

GSK3 BETA

RAB23

BETA TRCP

PRKACA

SUPPRESSOR OF FUSED

BMP2

BMP5

BMP6

BMP7

BMP8B

CSNK1A1L

CSNK1G1

CSNK1G2

DHH

GLI2

IHH

PRKACG

PRKX

PTCH2

SMOOTHENED

SONIC HEDGEHOG

WNT1

WNT10B

WNT3

WNT3A

WNT5A

WNT7A

ZIC2

GLI3

STK36

WNT4

Plasmids

Myc-DDK

mGFP

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-Myc-DDK

No

LentiORF

Druggable Genome

Secreted Protein

ES Cell Differentiation/IPS

Protein Kinase

Transmembrane

Cancer stem cells

Adult stem cells

Embryonic stem cells

Induced pluripotent stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Stem cell relevant signaling - Wnt Signaling pathway

Transcription Factors

Stem cell relevant signaling - DSL/Notch pathway

Protease

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Neuroactive ligand-receptor interaction

Cytokine-cytokine receptor interaction

Regulation of actin cytoskeleton

Focal adhesion

Chemokine signaling pathway

Calcium signaling pathway

Neurotrophin signaling pathway

Wnt signaling pathway

Jak-STAT signaling pathway

Insulin signaling pathway

Progesterone-mediated oocyte maturation

T cell receptor signaling pathway

Natural killer cell mediated cytotoxicity

Endocytosis

ErbB signaling pathway

Toll-like receptor signaling pathway

Axon guidance

Cell cycle

Apoptosis

Prostate cancer

Oocyte meiosis

Colorectal cancer

Purine metabolism

GnRH signaling pathway

Pancreatic cancer

Leukocyte transendothelial migration

Alzheimer's disease

Adherens junction

Hematopoietic cell lineage

Melanogenesis

Ubiquitin mediated proteolysis

Vascular smooth muscle contraction

Cell adhesion molecules (CAMs)

VEGF signaling pathway

Chronic myeloid leukemia

Gap junction

B cell receptor signaling pathway

Small cell lung cancer

Renal cell carcinoma

Melanoma

TGF-beta signaling pathway

Huntington's disease

Dilated cardiomyopathy

Fc epsilon RI signaling pathway

Tight junction

Fc gamma R-mediated phagocytosis

Glioma

p53 signaling pathway

NOD-like receptor signaling pathway

Hypertrophic cardiomyopathy (HCM)

Acute myeloid leukemia

Adipocytokine signaling pathway

Long-term potentiation

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Lysosome

Endometrial cancer

Long-term depression

Complement and coagulation cascades

RIG-I-like receptor signaling pathway

Non-small cell lung cancer

Olfactory transduction

Amyotrophic lateral sclerosis (ALS)

Phosphatidylinositol signaling system

Bladder cancer

ECM-receptor interaction

Epithelial cell signaling in Helicobacter pylori infection

PPAR signaling pathway

Type II diabetes mellitus

Basal cell carcinoma

mTOR signaling pathway

Glycolysis / Gluconeogenesis

Viral myocarditis

Hedgehog signaling pathway

Pathogenic Escherichia coli infection

Thyroid cancer

Inositol phosphate metabolism

Cytosolic DNA-sensing pathway

Cardiac muscle contraction

Drug metabolism - cytochrome P450

Metabolism of xenobiotics by cytochrome P450

Parkinson's disease

ABC transporters

Antigen processing and presentation

Retinol metabolism

Arginine and proline metabolism

Primary immunodeficiency

Valine

Pyrimidine metabolism

Glycerophospholipid metabolism

Arachidonic acid metabolism

Base excision repair

Tyrosine metabolism

Drug metabolism - other enzymes

Lysine degradation

Autoimmune thyroid disease

leucine and isoleucine degradation

Glycerolipid metabolism

Nucleotide excision repair

Systemic lupus erythematosus

Taste transduction

Prion diseases

Vibrio cholerae infection

Fructose and mannose metabolism

Sphingolipid metabolism

Fatty acid metabolism

Pyruvate metabolism

Starch and sucrose metabolism

Notch signaling pathway

Cysteine and methionine metabolism

Tryptophan metabolism

Galactose metabolism

Amino sugar and nucleotide sugar metabolism

Glutathione metabolism

Type I diabetes mellitus

SNARE interactions in vesicular transport

Maturity onset diabetes of the young

Regulation of autophagy

Butanoate metabolism

Homologous recombination

Androgen and estrogen metabolism

Linoleic acid metabolism

Alanine

Propanoate metabolism

aspartate and glutamate metabolism

Proteasome

Histidine metabolism

Renin-angiotensin system

Citrate cycle (TCA cycle)

Nitrogen metabolism

Oxidative phosphorylation

Pentose phosphate pathway

Allograft rejection

Ether lipid metabolism

Mismatch repair

Dorso-ventral axis formation

Spliceosome

Aminoacyl-tRNA biosynthesis

Glycosaminoglycan degradation

Phenylalanine metabolism

Porphyrin and chlorophyll metabolism

Graft-versus-host disease

Riboflavin metabolism

Non-homologous end-joining

Ribosome

beta-Alanine metabolism

DNA replication

Glycine

serine and threonine metabolism

Circadian rhythm - mammal

Other glycan degradation

C21-Steroid hormone metabolism

Pantothenate and CoA biosynthesis

Steroid biosynthesis

N-Glycan biosynthesis

Selenoamino acid metabolism

leucine and isoleucine biosynthesis

Primary bile acid biosynthesis

Asthma

alpha-Linolenic acid metabolism

Folate biosynthesis

Terpenoid backbone biosynthesis

Basal transcription factors

Ascorbate and aldarate metabolism

Nicotinate and nicotinamide metabolism

Pentose and glucuronate interconversions

RNA degradation

Glycosphingolipid biosynthesis - globo series

Glyoxylate and dicarboxylate metabolism

Limonene and pinene degradation

Synthesis and degradation of ketone bodies

One carbon pool by folate

Biosynthesis of unsaturated fatty acids

Glycosphingolipid biosynthesis - lacto and neolacto series

Thiamine metabolism

Glycosphingolipid biosynthesis - ganglio series

Caffeine metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Methane metabolism

Protein export

Taurine and hypotaurine metabolism

Fatty acid elongation in mitochondria

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Heparan sulfate biosynthesis

Sulfur metabolism

Fatty acid biosynthesis

Phenylalanine

tyrosine and tryptophan biosynthesis

O-Glycan biosynthesis

Vitamin B6 metabolism

RNA polymerase

Chondroitin sulfate biosynthesis

D-Arginine and D-ornithine metabolism

D-Glutamine and D-glutamate metabolism

Keratan sulfate biosynthesis

Biotin metabolism

Lysine biosynthesis

Puromycin

None

1

Yes

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