Expression Plasmids

cDNA Clones

Expression Plasmids

Human

JNK1

JNK2

SMAD2

AXIN 1

BETA CATENIN

CASEIN KINASE 1 ALPHA

CKII ALPHA

C-JUN

DISHEVELLED 2

DISHEVELLED 3

DKK1

DKK2

DKK4

DVL1

LEF1

PKC ALPHA

SFRP1

SFRP4

SFRP5

SMAD3

TCF7

WIF1

WNT1

WNT2

WNT3A

WNT5A

WNT6

WNT7B

WNT8A

WNT8B

Plasmids

Myc-DDK

pCMV6-Entry

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-Myc-DDK

No

LentiORF

Druggable Genome

Protein Kinase

ES Cell Differentiation/IPS

Transcription Factors

Transmembrane

Secreted Protein

Stem cell relevant signaling - Wnt Signaling pathway

Cancer stem cells

Phosphatase

Adult stem cells

GPCR

Stem cell relevant signaling - JAK/STAT signaling pathway

Embryonic stem cells

Stem cell - Pluripotency

Stem cell relevant signaling - TGFb/BMP signaling pathway

Induced pluripotent stem cells

Protease

Nuclear Hormone Receptor

Stem cell relevant signaling - DSL/Notch pathway

Pathways in cancer

Focal adhesion

Cytokine-cytokine receptor interaction

Wnt signaling pathway

Colorectal cancer

Hematopoietic cell lineage

MAPK signaling pathway

Regulation of actin cytoskeleton

Cell adhesion molecules (CAMs)

TGF-beta signaling pathway

Jak-STAT signaling pathway

Melanoma

ErbB signaling pathway

Pancreatic cancer

Basal cell carcinoma

Neurotrophin signaling pathway

Prostate cancer

Hedgehog signaling pathway

Leukocyte transendothelial migration

Acute myeloid leukemia

Maturity onset diabetes of the young

Melanogenesis

Adherens junction

Small cell lung cancer

ECM-receptor interaction

Endocytosis

Natural killer cell mediated cytotoxicity

Progesterone-mediated oocyte maturation

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Endometrial cancer

Insulin signaling pathway

T cell receptor signaling pathway

Chronic myeloid leukemia

Dilated cardiomyopathy

Fc epsilon RI signaling pathway

Fc gamma R-mediated phagocytosis

Glioma

Hypertrophic cardiomyopathy (HCM)

Toll-like receptor signaling pathway

Adipocytokine signaling pathway

GnRH signaling pathway

Tight junction

B cell receptor signaling pathway

Chemokine signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

Type II diabetes mellitus

Apoptosis

Renal cell carcinoma

Gap junction

Metabolic pathways

Non-small cell lung cancer

Notch signaling pathway

VEGF signaling pathway

mTOR signaling pathway

Pathogenic Escherichia coli infection

Systemic lupus erythematosus

Axon guidance

Huntington's disease

NOD-like receptor signaling pathway

RIG-I-like receptor signaling pathway

Prion diseases

Alzheimer's disease

Amyotrophic lateral sclerosis (ALS)

Calcium signaling pathway

Thyroid cancer

Antigen processing and presentation

Autoimmune thyroid disease

Bladder cancer

Cell cycle

Long-term depression

Oocyte meiosis

Primary immunodeficiency

Viral myocarditis

p53 signaling pathway

Allograft rejection

Dorso-ventral axis formation

Glycolysis / Gluconeogenesis

Lysosome

Neuroactive ligand-receptor interaction

Type I diabetes mellitus

ABC transporters

Complement and coagulation cascades

Graft-versus-host disease

Long-term potentiation

Nicotinate and nicotinamide metabolism

PPAR signaling pathway

Phosphatidylinositol signaling system

Retinol metabolism

Vascular smooth muscle contraction

Vibrio cholerae infection

Amino sugar and nucleotide sugar metabolism

Asthma

Cardiac muscle contraction

Citrate cycle (TCA cycle)

Drug metabolism - cytochrome P450

Drug metabolism - other enzymes

Fructose and mannose metabolism

Galactose metabolism

Glutathione metabolism

Inositol phosphate metabolism

Linoleic acid metabolism

Metabolism of xenobiotics by cytochrome P450

Oxidative phosphorylation

Parkinson's disease

Primary bile acid biosynthesis

Purine metabolism

Pyrimidine metabolism

Pyruvate metabolism

Regulation of autophagy

Renin-angiotensin system

Starch and sucrose metabolism

Tyrosine metabolism

Ubiquitin mediated proteolysis

None

1

Yes

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