United States
Germany
Japan
United Kingdom
China
EGFR Mutant (L747_S752del), Myc-DDK-tagged ORF clone of Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1 as transfection-ready DNA
| Mutation | L747_S752del |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
Mutant ORF Clones
RET Mutant (M918T), Myc-DDK-tagged ORF clone of Homo sapiens ret proto-oncogene (RET), transcript variant 2 as transfection-ready DNA
| Mutation | M918T |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
RET Mutant (v804M), Myc-DDK-tagged ORF clone of Homo sapiens ret proto-oncogene (RET), transcript variant 2 as transfection-ready DNA
| Mutation | v804M |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
BRCA1 Mutant (L1780P), Myc-DDK-tagged ORF clone of Homo sapiens breast Cancer, early onset (BRCA1), transcript variant 1 as transfection-ready DNA
| Mutation | L1780P |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MLH1 Mutant (E102D), Myc-DDK-tagged ORF clone of Homo sapiens mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (MLH1), transcript variant 1 as transfection-ready DNA
| Mutation | E102D |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MPL Mutant (W515K), Myc-DDK-tagged ORF clone of Homo sapiens myeloproliferative leukemia virus oncogene (MPL) as transfection-ready DNA
| Mutation | W515K |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
NRAS mutant (Q61H), Myc-DDK-tagged ORF clone of Homo sapiens neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS) as transfection-ready DNA
| Mutation | Q61H |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
KRAS mutant (Q61R), Myc-DDK-tagged ORF clone of Homo sapiens v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS), transcript variant b as transfection-ready DNA
| Mutation | Q61R |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
NRAS mutant (G13D), Myc-DDK-tagged ORF clone of Homo sapiens neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS) as transfection-ready DNA
| Mutation | G13D |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
HRAS mutant (G12D), Myc-DDK-tagged ORF clone of Homo sapiens v-Ha-ras Harvey rat sarcoma viral oncogene homolog (HRAS), transcript variant 1 as transfection-ready DNA
| Mutation | G12D |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
TP53 mutant (R213X), Myc-DDK-tagged ORF clone of Homo sapiens tumor protein p53 (TP53), transcript variant 1 as transfection-ready DNA
| Mutation | R213X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
RAF1 Mutant (P261A), Myc-DDK-tagged ORF clone of Homo sapiens v-raf-1 murine leukemia viral oncogene homolog 1 (RAF1) as transfection-ready
| Mutation | P261A |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
CDKN2A Mutant (G101W), Myc-DDK-tagged ORF clone of Homo sapiens cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) (CDKN2A), transcript variant 1 as transfection-ready DNA
| Mutation | G101W |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
KRAS mutant (Q61H), Myc-DDK-tagged ORF clone of Homo sapiens v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS), transcript variant b as transfection-ready DNA
| Mutation | Q61H |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
HRAS Mutant (G13D), Myc-DDK-tagged ORF clone of Homo sapiens v-Ha-ras Harvey rat sarcoma viral oncogene homolog (HRAS), transcript variant 1 as transfection-ready DNA
| Mutation | G13D |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
活动过滤器
优化搜索结果
Species
Target Symbol
- BRCA1 (388)
- BTK (291)
- BRCA2 (273)
- GCK (249)
- TSC2 (240)
- MEN1 (237)
- MLH1 (233)
- MSH2 (212)
- RET (179)
- NOTCH3 (156)
- NF2 (87)
- MSH6 (83)
- STK11 (78)
- PI 3 KINASE CATALYTIC SUBUNIT ALPHA (67)
- WT1 (62)
- FH (60)
- FGFR1 (53)
- GNAS (47)
- PTEN (43)
- EGFR (39)
- ERCC2 (37)
- BRAF (34)
- FLT4 (33)
- CTNNB1 (32)
- TERT (30)
- CBL (24)
- CDKN2A (23)
- KRAS (21)
- PRKCG (21)
- HRAS (18)
- RAF1 (18)
- NRAS (17)
- ROR2 (16)
- BETA CATENIN (14)
- ALK (13)
- MAP2K2 (12)
- GPC3 (11)
- CDKN1C (10)
- GRK1 (10)
- MYCN (10)
- AMHR2 (9)
- B RAF (9)
- BUB1B (9)
- MET (9)
- CDH1 (8)
- LPAR6 (7)
- MAP2K1 (7)
- ACTIVIN RECEPTOR TYPE IA (6)
- GATA1 (6)
- MERTK (6)
- P21 RAS (6)
- AXIN1 (5)
- CBLB (5)
- ISOCITRATE DEHYDROGENASE (5)
- RB1 (5)
- ZAP70 (5)
- CDK4 (4)
- EPHX1 (4)
- LKB1 (4)
- PAK3 (4)
- STAT1 (4)
- TPOR (4)
- TYK2 (4)
- XRCC1 (4)
- ACVR1 (3)
- AURKA (3)
- AXIN2 (3)
- CDKN1B (3)
- DDR2 (3)
- GRK4 (3)
- IDH2 (3)
- MAF (3)
- MEK1 (3)
- SERPIND1 (3)
- AKT1 (2)
- MYBL2 (2)
- MYC (2)
- TEK (2)
- AURKC (1)
- BCL2 (1)
- BUBR1 (1)
- CDK7 (1)
- CSF1R (1)
- EPHA2 (1)
- ERBB2 (1)
- FGFR4 (1)
- FLT3 (1)
- FRK (1)
- GRK5 (1)
- HIF-1 ALPHA (1)
- HIF1A (1)
- HOXB13 (1)
- INTEGRIN LINKED KINASE (1)
- IRAK1 (1)
- JAG2 (1)
- LTK (1)
- LYN (1)
- MASTL (1)
- MST1R (1)
- MYO3A (1)
Tags
Mutants
Brands
Families
- Druggable Genome (3680)
- Protein Kinase (914)
- Transcription Factors (833)
- Transmembrane (386)
- Stem cell - Pluripotency (320)
- ES Cell Differentiation/IPS (123)
- Secreted Protein (86)
- Adult stem cells (45)
- Phosphatase (43)
- Stem cell relevant signaling - JAK/STAT signaling pathway (41)
- Cancer stem cells (39)
- GPCR (7)
- Stem cell relevant signaling - Wnt Signaling pathway (7)
- Induced pluripotent stem cells (5)
- Protease (4)
- Embryonic stem cells (2)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (2)
Pathways
- Pathways in cancer (1561)
- Colorectal cancer (795)
- Insulin signaling pathway (732)
- Endometrial cancer (596)
- Mismatch repair (528)
- Pancreatic cancer (512)
- B cell receptor signaling pathway (463)
- Fc epsilon RI signaling pathway (463)
- mTOR signaling pathway (436)
- Ubiquitin mediated proteolysis (417)
- Prostate cancer (407)
- Melanoma (400)
- Thyroid cancer (363)
- Focal adhesion (362)
- Glioma (351)
- Metabolic pathways (318)
- Type II diabetes mellitus (316)
- ErbB signaling pathway (314)
- p53 signaling pathway (312)
- Non-small cell lung cancer (310)
- Regulation of actin cytoskeleton (309)
- Endocytosis (296)
- Primary immunodeficiency (296)
- Renal cell carcinoma (289)
- Chronic myeloid leukemia (283)
- Homologous recombination (273)
- MAPK signaling pathway (264)
- Amino sugar and nucleotide sugar metabolism (249)
- Galactose metabolism (249)
- Glycolysis / Gluconeogenesis (249)
- Maturity onset diabetes of the young (249)
- Starch and sucrose metabolism (249)
- Natural killer cell mediated cytotoxicity (238)
- Bladder cancer (230)
- Dorso-ventral axis formation (226)
- Chemokine signaling pathway (221)
- Acute myeloid leukemia (217)
- Neurotrophin signaling pathway (217)
- Melanogenesis (216)
- Long-term depression (214)
- T cell receptor signaling pathway (213)
- Gap junction (209)
- VEGF signaling pathway (192)
- GnRH signaling pathway (188)
- Tight junction (179)
- Long-term potentiation (166)
- Progesterone-mediated oocyte maturation (161)
- Notch signaling pathway (157)
- Adherens junction (156)
- Vascular smooth muscle contraction (152)
- Leukocyte transendothelial migration (134)
- Phosphatidylinositol signaling system (132)
- Small cell lung cancer (129)
- Fc gamma R-mediated phagocytosis (119)
- Jak-STAT signaling pathway (112)
- Inositol phosphate metabolism (111)
- Calcium signaling pathway (108)
- Cytokine-cytokine receptor interaction (105)
- Toll-like receptor signaling pathway (96)
- Adipocytokine signaling pathway (84)
- Wnt signaling pathway (78)
- Axon guidance (76)
- Apoptosis (72)
- Citrate cycle (TCA cycle) (68)
- Vibrio cholerae infection (68)
- Cell cycle (61)
- Basal cell carcinoma (55)
- Pathogenic Escherichia coli infection (54)
- Epithelial cell signaling in Helicobacter pylori infection (49)
- Dilated cardiomyopathy (47)
- Taste transduction (47)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (46)
- Nucleotide excision repair (38)
- Prion diseases (22)
- TGF-beta signaling pathway (20)
- Oocyte meiosis (13)
- Cell adhesion molecules (CAMs) (8)
- Glutathione metabolism (8)
- Neuroactive ligand-receptor interaction (7)
- Base excision repair (4)
- Metabolism of xenobiotics by cytochrome P450 (4)
- Complement and coagulation cascades (3)
- Amyotrophic lateral sclerosis (ALS) (2)
- Hematopoietic cell lineage (2)
- Huntington's disease (1)
- PPAR signaling pathway (1)
