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IDH2 mutant (R172G), Myc-DDK-tagged ORF clone of Homo sapiens isocitrate dehydrogenase 2 (NADP+), mitochondrial (IDH2), nuclear gene encoding mitochondrial protein as transfection-ready DNA
| Mutation | R172G |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
cDNA Clones
PTEN Mutant (P247fs*5), Myc-DDK-tagged ORF clone of Homo sapiens phosphatase and tensin homolog (PTEN) as transfection-ready DNA
| Mutation | P247fs*5 |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
Myc-DDK-tagged ORF clone of viral ORF for NS5A protein [Hepatitis C virus], codon optimized for human cell expression, NP_751927
| Type | Virus Tagged ORF Clone |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
Myc-DDK-tagged ORF clone of viral ORF for envelope protein US28 [Human herpesvirus 5], codon optimized for human cell expression, YP_081612
| Type | Virus Tagged ORF Clone |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
Myc-DDK-tagged ORF clone of viral ORF for nonstructural protein NS4A [Zika virus, strain MR766], codon optimized for human cell expression, YP_009227203.1
| Type | Virus Tagged ORF Clone |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
Myc-DDK-tagged ORF clone for spike protein [Human coronavirus NL63], codon optimized for human cell expression, YP_003767
| Type | Virus Tagged ORF Clone |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
CTNNB1 Mutant (S37F), Myc-DDK-tagged ORF clone of Homo sapiens catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), transcript variant 1 as transfection-ready DNA
| Mutation | S37F |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
ILK Mutant (A262V), Myc-DDK-tagged ORF clone of Homo sapiens integrin-linked kinase (ILK), transcript variant 1 as transfection-ready DNA
| Mutation | A262V |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
Myc-DDK-tagged ORF clone for SARS-CoV-2 surface glycoprotein mutant (D614G) [Severe acute respiratory syndrome coronavirus 2], YP_009724390
| Type | Virus Tagged ORF Clone |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
活动过滤器
优化搜索结果
Target Symbol
- KRAS (7)
- CD44 (6)
- ISOCITRATE DEHYDROGENASE (6)
- AKT1 (5)
- AMYLOID PRECURSOR PROTEIN (4)
- BDNF (4)
- CAMK2A (4)
- EGFR (4)
- FOXM1 (4)
- GATA2 (4)
- GPBAR1 (4)
- MITF (4)
- P63 (4)
- RUNX2 (4)
- STAT3 (4)
- ABCG2 (3)
- ACSL1 (3)
- ATG9A (3)
- BACE1 (3)
- BETA CATENIN (3)
- CDK4 (3)
- CREB1 (3)
- CXCR4 (3)
- DDIT3 (3)
- DHCR7 (3)
- DPP6 (3)
- FOXA2 (3)
- FSTL1 (3)
- GAPDH (3)
- GLUCOCORTICOID RECEPTOR (3)
- HNF 4 ALPHA (3)
- IDH2 (3)
- IL18 (3)
- IL1F10 (3)
- IRAK (3)
- IRF1 (3)
- LAMP2 (3)
- LDHA (3)
- LIFR (3)
- LRP5 (3)
- MET (3)
- MU OPIOID RECEPTOR (3)
- NFIB (3)
- NRP2 (3)
- NUMB (3)
- P53 (3)
- PD-L1 (3)
- PITX2 (3)
- PLEXIN A4 (3)
- PODXL (3)
- PRKACA (3)
- PTEN (3)
- RET (3)
- RHOT1 (3)
- RNF146 (3)
- S PROTEIN (3)
- SIDT1 (3)
- SIRT1 (3)
- SLC22A24 (3)
- SLC22A6 (3)
- SLC2A6 (3)
- SOD2 (3)
- SQSTM1 (3)
- TAU (3)
- TRPA1 (3)
- TRPC6 (3)
- TSPAN7 (3)
- TXNIP (3)
- UCP2 (3)
- VEGFA (3)
- YBX3 (3)
- 5HT3A RECEPTOR (2)
- ABL2 (2)
- ACAT1 (2)
- ACOT1 (2)
- ACSL3 (2)
- ADAM22 (2)
- ADAM23 (2)
- ADAR1 (2)
- AGTR1A (2)
- AICDA (2)
- AKIRIN2 (2)
- AKR1A1 (2)
- AKR1D1 (2)
- AKT3 (2)
- ALDH1A1 (2)
- ALKALINE PHOSPHATASE (2)
- ALOX15 (2)
- ALPHA SYNUCLEIN (2)
- ALY (2)
- ANDROGEN RECEPTOR (2)
- ANGIOTENSIN II TYPE 1 RECEPTOR (2)
- ANNEXIN A2 (2)
- ANO6 (2)
- APC (2)
- APOLIPOPROTEIN E (2)
- AQUAPORIN 1 (2)
- AREB6 (2)
- ARF6 (2)
- ARG2 (2)
Families
- Druggable Genome (2247)
- Transmembrane (1121)
- Transcription Factors (567)
- Secreted Protein (335)
- ES Cell Differentiation/IPS (240)
- Protein Kinase (229)
- Protease (122)
- Stem cell - Pluripotency (122)
- GPCR (106)
- Adult stem cells (61)
- Embryonic stem cells (49)
- Ion Channels: Other (44)
- Phosphatase (43)
- Cancer stem cells (38)
- Nuclear Hormone Receptor (38)
- Induced pluripotent stem cells (31)
- Ion Channels: Potassium (29)
- Ion Channels: Cys-loop Receptors (21)
- P450 (19)
- Stem cell relevant signaling - DSL/Notch pathway (18)
- Stem cell relevant signaling - JAK/STAT signaling pathway (18)
- Ion Channels: Transient receptor potential (16)
- Stem cell relevant signaling - Wnt Signaling pathway (14)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (11)
- Ion Channels: Glutamate Receptors (9)
- Ion Channels: Sodium (9)
- Ion Channels: Calcium (3)
- Ion Channels: ATP Receptors (2)
Pathways
- Metabolic pathways (303)
- Pathways in cancer (235)
- MAPK signaling pathway (152)
- Focal adhesion (111)
- Regulation of actin cytoskeleton (110)
- Cytokine-cytokine receptor interaction (106)
- Neuroactive ligand-receptor interaction (101)
- Chemokine signaling pathway (100)
- Neurotrophin signaling pathway (93)
- Jak-STAT signaling pathway (89)
- T cell receptor signaling pathway (87)
- Insulin signaling pathway (84)
- Prostate cancer (84)
- Wnt signaling pathway (83)
- Endocytosis (77)
- Axon guidance (76)
- Colorectal cancer (76)
- ErbB signaling pathway (76)
- Alzheimer's disease (74)
- Calcium signaling pathway (72)
- Chronic myeloid leukemia (71)
- Melanoma (71)
- Huntington's disease (69)
- Renal cell carcinoma (67)
- Tight junction (66)
- Endometrial cancer (65)
- Natural killer cell mediated cytotoxicity (65)
- Pancreatic cancer (65)
- Cell cycle (63)
- Toll-like receptor signaling pathway (62)
- Apoptosis (61)
- Glioma (60)
- Leukocyte transendothelial migration (60)
- Melanogenesis (60)
- GnRH signaling pathway (59)
- VEGF signaling pathway (59)
- B cell receptor signaling pathway (58)
- Ubiquitin mediated proteolysis (58)
- Acute myeloid leukemia (57)
- Small cell lung cancer (57)
- Non-small cell lung cancer (56)
- Progesterone-mediated oocyte maturation (56)
- Fc epsilon RI signaling pathway (54)
- Adherens junction (53)
- Cell adhesion molecules (CAMs) (53)
- TGF-beta signaling pathway (53)
- Fc gamma R-mediated phagocytosis (52)
- Gap junction (50)
- Bladder cancer (49)
- Hematopoietic cell lineage (49)
- Lysosome (46)
- p53 signaling pathway (46)
- Adipocytokine signaling pathway (45)
- Vascular smooth muscle contraction (45)
- Oocyte meiosis (44)
- RIG-I-like receptor signaling pathway (44)
- Parkinson's disease (43)
- Long-term potentiation (42)
- Long-term depression (41)
- Purine metabolism (40)
- mTOR signaling pathway (40)
- Thyroid cancer (39)
- Epithelial cell signaling in Helicobacter pylori infection (36)
- Pathogenic Escherichia coli infection (34)
- Spliceosome (34)
- Basal cell carcinoma (33)
- Dilated cardiomyopathy (33)
- NOD-like receptor signaling pathway (32)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (31)
- ECM-receptor interaction (31)
- Type II diabetes mellitus (31)
- Amyotrophic lateral sclerosis (ALS) (30)
- Oxidative phosphorylation (30)
- Cytosolic DNA-sensing pathway (29)
- Hypertrophic cardiomyopathy (HCM) (29)
- PPAR signaling pathway (29)
- Hedgehog signaling pathway (28)
- Systemic lupus erythematosus (27)
- Glutathione metabolism (25)
- Metabolism of xenobiotics by cytochrome P450 (25)
- Notch signaling pathway (25)
- Citrate cycle (TCA cycle) (24)
- Dorso-ventral axis formation (24)
- Glycolysis / Gluconeogenesis (23)
- Antigen processing and presentation (22)
- Cardiac muscle contraction (22)
- Maturity onset diabetes of the young (22)
- Prion diseases (22)
- Viral myocarditis (22)
- Drug metabolism - cytochrome P450 (21)
- Vibrio cholerae infection (20)
- Proteasome (19)
- Phosphatidylinositol signaling system (18)
- Pyruvate metabolism (18)
- Sphingolipid metabolism (18)
- Arginine and proline metabolism (17)
- Glycerophospholipid metabolism (17)
- Inositol phosphate metabolism (16)
- Retinol metabolism (16)
- Type I diabetes mellitus (16)
- Arachidonic acid metabolism (15)
- Lysine degradation (15)
- Pyrimidine metabolism (15)
- Allograft rejection (14)
- Autoimmune thyroid disease (14)
- Complement and coagulation cascades (14)
- Tryptophan metabolism (14)
- ABC transporters (13)
- Cysteine and methionine metabolism (13)
- DNA replication (13)
- Drug metabolism - other enzymes (13)
- Olfactory transduction (13)
- Primary immunodeficiency (13)
- Regulation of autophagy (13)
- Androgen and estrogen metabolism (12)
- Fatty acid metabolism (12)
- Fructose and mannose metabolism (12)
- N-Glycan biosynthesis (12)
- Starch and sucrose metabolism (12)
- Valine (12)
- Glycine (11)
- Graft-versus-host disease (11)
- Nicotinate and nicotinamide metabolism (11)
- Nucleotide excision repair (11)
- RNA degradation (11)
- Ribosome (11)
- Taste transduction (11)
- Tyrosine metabolism (11)
- serine and threonine metabolism (11)
- Alanine (10)
- Base excision repair (10)
- Butanoate metabolism (10)
- Mismatch repair (10)
- Nitrogen metabolism (10)
- SNARE interactions in vesicular transport (10)
- aspartate and glutamate metabolism (10)
- leucine and isoleucine degradation (10)
- Asthma (9)
- Galactose metabolism (9)
- Glycerolipid metabolism (9)
- Homologous recombination (9)
- Linoleic acid metabolism (9)
- Propanoate metabolism (9)
- Glycosphingolipid biosynthesis - lacto and neolacto series (8)
- Renin-angiotensin system (8)
- Selenoamino acid metabolism (8)
- Aminoacyl-tRNA biosynthesis (7)
- C21-Steroid hormone metabolism (7)
- Ether lipid metabolism (7)
- Glycosaminoglycan degradation (7)
- Pentose phosphate pathway (7)
- Phenylalanine metabolism (7)
- Porphyrin and chlorophyll metabolism (7)
- Steroid biosynthesis (7)
- Amino sugar and nucleotide sugar metabolism (6)
- Biosynthesis of unsaturated fatty acids (6)
- Chondroitin sulfate biosynthesis (6)
- Heparan sulfate biosynthesis (6)
- Histidine metabolism (6)
- Keratan sulfate biosynthesis (6)
- Non-homologous end-joining (6)
- O-Glycan biosynthesis (6)
- Limonene and pinene degradation (5)
- One carbon pool by folate (5)
- Other glycan degradation (5)
- Primary bile acid biosynthesis (5)
- alpha-Linolenic acid metabolism (5)
- beta-Alanine metabolism (5)
- Ascorbate and aldarate metabolism (4)
- Glyoxylate and dicarboxylate metabolism (4)
- Methane metabolism (4)
- Pantothenate and CoA biosynthesis (4)
- Pentose and glucuronate interconversions (4)
- RNA polymerase (4)
- Sulfur metabolism (4)
- Synthesis and degradation of ketone bodies (4)
- Caffeine metabolism (3)
- Folate biosynthesis (3)
- Riboflavin metabolism (3)
- Terpenoid backbone biosynthesis (3)
- leucine and isoleucine biosynthesis (3)
- Basal transcription factors (2)
- Circadian rhythm - mammal (2)
- Cyanoamino acid metabolism (2)
- D-Glutamine and D-glutamate metabolism (2)
- Fatty acid elongation in mitochondria (2)
- Glycosphingolipid biosynthesis - ganglio series (2)
- Glycosphingolipid biosynthesis - globo series (2)
- Phenylalanine (2)
- Taurine and hypotaurine metabolism (2)
- Thiamine metabolism (2)
- tyrosine and tryptophan biosynthesis (2)
- Biotin metabolism (1)
- Fatty acid biosynthesis (1)
- O-Mannosyl glycan biosynthesis (1)
- Protein export (1)
- Ubiquinone and other terpenoid-quinone biosynthesis (1)
- Vitamin B6 metabolism (1)
