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GRK4 Mutant (A142V), Myc-DDK-tagged ORF clone of Homo sapiens G protein-coupled receptor kinase 4 (GRK4), transcript variant 1 as transfection-ready DNA
| Mutation | A142V |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
cDNA Clones
MET Mutant (V1220D), Myc-DDK-tagged ORF clone of Homo sapiens met proto-oncogene (hepatocyte growth factor receptor) (MET), transcript variant 2 as transfection-ready DNA
| Mutation | V1220D |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
EGFR Mutant (L747_E749del), Myc-DDK-tagged ORF clone of Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1 as transfection-ready DNA
| Mutation | L747_E749del |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
HRAS mutant (Q61L), Myc-DDK-tagged ORF clone of Homo sapiens v-Ha-ras Harvey rat sarcoma viral oncogene homolog (HRAS), transcript variant 1 as transfection-ready DNA
| Mutation | Q61L |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
ATP2B1 (Myc-DDK-tagged)-Human ATPase, Ca++ transporting, plasma membrane 1 (ATP2B1), transcript variant 2. Note: ORF is codon optimized
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Vector | pCMV6-AC-Myc-DDK |
- TrueORF®
FNBP1L (Myc-DDK-tagged)-Human formin binding protein 1-like (FNBP1L), transcript variant 1. Note: ORF is codon optimized
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
Nemf (Myc-DDK-tagged) - Mouse nuclear export mediator factor (Nemf)
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
活动过滤器
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Species
Target Symbol
- P53 (97)
- EGFR (24)
- KRAS (22)
- BDNF (21)
- PLAGL1 (21)
- DISC1 (18)
- BETA CATENIN (17)
- MU OPIOID RECEPTOR (17)
- MORTALITY FACTOR 4 LIKE 2 (16)
- MYADM (16)
- NRG1 (16)
- PDE9A (16)
- VEGFA (16)
- CD44 (14)
- CONSTITUTIVE ANDROSTANE RECEPTOR (14)
- KCNJ15 (14)
- NRAS (14)
- ALPHA DYSTROGLYCAN (13)
- EIF5A (13)
- RHOH (13)
- RUNX1T1 (13)
- CD46 (12)
- ESTROGEN RELATED RECEPTOR GAMMA (12)
- HEXIM2 (12)
- HMGA1 (12)
- NCALD (12)
- PI 3 KINASE CATALYTIC SUBUNIT ALPHA (12)
- SHUGOSHIN (12)
- SSH3BP1 (12)
- SYNTABULIN (12)
- ALPHA 1 ANTITRYPSIN (11)
- APC11 (11)
- BIN1 (11)
- CAMK2B (11)
- DYSTROBREVIN ALPHA (11)
- FGF1 (11)
- IL1RAP (11)
- ISLR2 (11)
- MET (11)
- MID1 (11)
- NAT1 (11)
- NDRG2 (11)
- PAX6 (11)
- PEX2 (11)
- PMP22 (11)
- TCF7L2 (11)
- APRATAXIN (10)
- ARPP21 (10)
- B RAF (10)
- BHLHB9 (10)
- CARHSP1 (10)
- CCR6 (10)
- CD36 (10)
- CHRM2 (10)
- DNMT3B (10)
- FAM156A (10)
- FHL1 (10)
- HNF 4 ALPHA (10)
- MBNL1 (10)
- NIPA2 (10)
- PTGER3 (10)
- RET (10)
- RNF146 (10)
- SLC16A3 (10)
- SLITRK2 (10)
- SOCS2 (10)
- SPHK1 (10)
- STEAP2 (10)
- TGIF (10)
- TJAP1 (10)
- TMEM176B (10)
- TMEM9 (10)
- TTC23 (10)
- UBE2D3 (10)
- YAP1 (10)
- ABL2 (9)
- C11ORF51 (9)
- C19ORF48 (9)
- C6ORF48 (9)
- CACNB2 (9)
- CAMK2D (9)
- CAMK2G (9)
- CD82 (9)
- CEACAM1 (9)
- FGFR1 (9)
- FIGNL1 (9)
- FRS2 (9)
- KCNE1 (9)
- LY6E (9)
- LYRM1 (9)
- MAGEA2 (9)
- MEF2A (9)
- MEF2C (9)
- MEIS2 (9)
- MIER1 (9)
- MITF (9)
- NEK6 (9)
- NF2 (9)
- P21 RAS (9)
- P2Y6 (9)
Mutants
Families
- Druggable Genome (11086)
- Transmembrane (7158)
- Transcription Factors (3059)
- Secreted Protein (1862)
- Protein Kinase (911)
- Protease (663)
- ES Cell Differentiation/IPS (653)
- Stem cell - Pluripotency (608)
- GPCR (495)
- Phosphatase (284)
- Ion Channels: Other (217)
- Adult stem cells (171)
- Nuclear Hormone Receptor (139)
- Embryonic stem cells (130)
- Ion Channels: Potassium (125)
- Cancer stem cells (87)
- Induced pluripotent stem cells (71)
- Ion Channels: Cys-loop Receptors (70)
- P450 (70)
- Stem cell relevant signaling - JAK/STAT signaling pathway (56)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (38)
- Ion Channels: Transient receptor potential (34)
- Ion Channels: Glutamate Receptors (29)
- Stem cell relevant signaling - Wnt Signaling pathway (28)
- Stem cell relevant signaling - DSL/Notch pathway (27)
- Ion Channels: Sodium (19)
- Ion Channels: Calcium (18)
- Ion Channels: ATP Receptors (13)
- Ion Channels: Cyclic nucleotide gated (9)
Pathways
- Metabolic pathways (1655)
- Pathways in cancer (835)
- MAPK signaling pathway (664)
- Cytokine-cytokine receptor interaction (450)
- Neuroactive ligand-receptor interaction (449)
- Regulation of actin cytoskeleton (432)
- Neurotrophin signaling pathway (415)
- Olfactory transduction (411)
- Focal adhesion (404)
- Wnt signaling pathway (379)
- Chemokine signaling pathway (363)
- Prostate cancer (363)
- Huntington's disease (343)
- Endocytosis (336)
- Colorectal cancer (332)
- Calcium signaling pathway (329)
- Melanoma (323)
- Cell cycle (314)
- Glioma (302)
- Pancreatic cancer (302)
- Chronic myeloid leukemia (293)
- Endometrial cancer (292)
- Insulin signaling pathway (283)
- Natural killer cell mediated cytotoxicity (281)
- Apoptosis (273)
- Non-small cell lung cancer (270)
- Purine metabolism (269)
- ErbB signaling pathway (266)
- Tight junction (266)
- Axon guidance (263)
- Jak-STAT signaling pathway (262)
- Ubiquitin mediated proteolysis (256)
- Bladder cancer (251)
- Small cell lung cancer (250)
- Alzheimer's disease (249)
- Progesterone-mediated oocyte maturation (247)
- T cell receptor signaling pathway (247)
- GnRH signaling pathway (233)
- Melanogenesis (233)
- Thyroid cancer (231)
- Leukocyte transendothelial migration (228)
- p53 signaling pathway (227)
- Oocyte meiosis (219)
- Cell adhesion molecules (CAMs) (212)
- Renal cell carcinoma (203)
- Adherens junction (202)
- Gap junction (200)
- VEGF signaling pathway (199)
- Amyotrophic lateral sclerosis (ALS) (194)
- Basal cell carcinoma (193)
- Lysosome (192)
- Vascular smooth muscle contraction (191)
- B cell receptor signaling pathway (187)
- Acute myeloid leukemia (186)
- Toll-like receptor signaling pathway (185)
- Fc gamma R-mediated phagocytosis (180)
- Hematopoietic cell lineage (178)
- Fc epsilon RI signaling pathway (177)
- Dilated cardiomyopathy (172)
- Long-term potentiation (169)
- Systemic lupus erythematosus (168)
- Long-term depression (164)
- Spliceosome (163)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (161)
- Parkinson's disease (161)
- Hypertrophic cardiomyopathy (HCM) (156)
- Pyrimidine metabolism (152)
- Oxidative phosphorylation (150)
- Antigen processing and presentation (142)
- TGF-beta signaling pathway (140)
- Viral myocarditis (138)
- Epithelial cell signaling in Helicobacter pylori infection (131)
- Complement and coagulation cascades (130)
- ECM-receptor interaction (129)
- Adipocytokine signaling pathway (128)
- mTOR signaling pathway (127)
- PPAR signaling pathway (126)
- NOD-like receptor signaling pathway (123)
- Ribosome (120)
- Phosphatidylinositol signaling system (117)
- RIG-I-like receptor signaling pathway (113)
- Pathogenic Escherichia coli infection (111)
- Glycolysis / Gluconeogenesis (110)
- Cardiac muscle contraction (107)
- Glycerophospholipid metabolism (103)
- Type II diabetes mellitus (103)
- Drug metabolism - cytochrome P450 (101)
- Metabolism of xenobiotics by cytochrome P450 (98)
- Inositol phosphate metabolism (92)
- Vibrio cholerae infection (90)
- Cytosolic DNA-sensing pathway (88)
- Glutathione metabolism (87)
- Arginine and proline metabolism (86)
- Valine (82)
- Drug metabolism - other enzymes (81)
- RNA degradation (81)
- Retinol metabolism (81)
- Hedgehog signaling pathway (80)
- Dorso-ventral axis formation (78)
- Arachidonic acid metabolism (74)
- N-Glycan biosynthesis (74)
- Taste transduction (74)
- Primary immunodeficiency (72)
- Tyrosine metabolism (71)
- Autoimmune thyroid disease (70)
- Notch signaling pathway (69)
- Pyruvate metabolism (69)
- leucine and isoleucine degradation (69)
- Lysine degradation (67)
- Sphingolipid metabolism (67)
- Starch and sucrose metabolism (67)
- Fatty acid metabolism (66)
- Type I diabetes mellitus (66)
- Amino sugar and nucleotide sugar metabolism (65)
- Glycerolipid metabolism (65)
- ABC transporters (64)
- Base excision repair (61)
- Proteasome (60)
- Graft-versus-host disease (59)
- Nucleotide excision repair (59)
- Cysteine and methionine metabolism (58)
- Prion diseases (58)
- Tryptophan metabolism (57)
- Alanine (56)
- Porphyrin and chlorophyll metabolism (56)
- aspartate and glutamate metabolism (56)
- Citrate cycle (TCA cycle) (55)
- SNARE interactions in vesicular transport (55)
- Androgen and estrogen metabolism (53)
- Allograft rejection (52)
- DNA replication (51)
- Ether lipid metabolism (51)
- Fructose and mannose metabolism (50)
- Homologous recombination (50)
- Maturity onset diabetes of the young (50)
- Butanoate metabolism (49)
- Propanoate metabolism (49)
- Glycosphingolipid biosynthesis - lacto and neolacto series (47)
- Aminoacyl-tRNA biosynthesis (46)
- Regulation of autophagy (45)
- Galactose metabolism (44)
- Pentose phosphate pathway (43)
- Glycine (42)
- Selenoamino acid metabolism (42)
- serine and threonine metabolism (42)
- Basal transcription factors (41)
- Nitrogen metabolism (41)
- O-Glycan biosynthesis (41)
- Glycosaminoglycan degradation (40)
- Asthma (39)
- Histidine metabolism (39)
- RNA polymerase (39)
- Linoleic acid metabolism (38)
- Nicotinate and nicotinamide metabolism (38)
- Mismatch repair (37)
- Phenylalanine metabolism (36)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (31)
- Pentose and glucuronate interconversions (31)
- Biosynthesis of unsaturated fatty acids (30)
- Chondroitin sulfate biosynthesis (29)
- Heparan sulfate biosynthesis (29)
- Sulfur metabolism (29)
- beta-Alanine metabolism (29)
- Non-homologous end-joining (28)
- Pantothenate and CoA biosynthesis (28)
- Primary bile acid biosynthesis (28)
- Keratan sulfate biosynthesis (27)
- Riboflavin metabolism (27)
- Ascorbate and aldarate metabolism (26)
- One carbon pool by folate (26)
- Renin-angiotensin system (26)
- Glycosphingolipid biosynthesis - globo series (25)
- Other glycan degradation (25)
- alpha-Linolenic acid metabolism (24)
- Glycosphingolipid biosynthesis - ganglio series (22)
- Glyoxylate and dicarboxylate metabolism (22)
- Steroid biosynthesis (22)
- Terpenoid backbone biosynthesis (22)
- Circadian rhythm - mammal (21)
- leucine and isoleucine biosynthesis (20)
- C21-Steroid hormone metabolism (19)
- Taurine and hypotaurine metabolism (19)
- Caffeine metabolism (17)
- Limonene and pinene degradation (17)
- Cyanoamino acid metabolism (15)
- Folate biosynthesis (14)
- Synthesis and degradation of ketone bodies (14)
- Fatty acid biosynthesis (12)
- Fatty acid elongation in mitochondria (12)
- Protein export (12)
- Thiamine metabolism (12)
- Ubiquinone and other terpenoid-quinone biosynthesis (10)
- Phenylalanine (9)
- tyrosine and tryptophan biosynthesis (9)
- Lipoic acid metabolism (8)
- Methane metabolism (7)
- Lysine biosynthesis (6)
- Biotin metabolism (5)
- Vitamin B6 metabolism (5)
- D-Glutamine and D-glutamate metabolism (4)
- O-Mannosyl glycan biosynthesis (4)
- D-Arginine and D-ornithine metabolism (1)
