cDNA Clones

cDNA Clones

Mutant ORF Clones

Expression Plasmids

Human

TSC2

P53

PTEN

CDKN2A

P73

BAX

BID

MDMX

SHISA5

CASPASE 8

CYCLIN D3

PIRH2

APAF1

CDK4

MDM2

P21

CDK1

SESN1

BCL2 BINDING COMPONENT 3

CHK2

CYCLIN B3

CYCLIN E1

EI24

GADD45A

P16INK4A

P53 AIP1

SESN3

SKP2

TUBERIN

ATM

ATR

CASPASE 3

CASPASE 9

CD82

CD95

CDK2

CHK1

COP1

CYCLIN B1

CYCLIN G

DDB2

IGF1

LRDD

P53R2

PIG3

RRM2

Myc-DDK

TurboGFP

pCMV6-Entry

pCMV6-AC-Myc-DDK

pCMV6-AN-Myc-DDK

Yes

No

TrueORF

LentiORF

TrueORF Gold, TrueORF

Druggable Genome

Transcription Factors

Stem cell - Pluripotency

Phosphatase

Transmembrane

Protein Kinase

Protease

ES Cell Differentiation/IPS

Secreted Protein

Stem cell relevant signaling - DSL/Notch pathway

Pathways in cancer

Metabolic pathways

Colorectal cancer

Insulin signaling pathway

Endometrial cancer

MAPK signaling pathway

Pancreatic cancer

Prostate cancer

Melanoma

Focal adhesion

Ubiquitin mediated proteolysis

Regulation of actin cytoskeleton

Mismatch repair

B cell receptor signaling pathway

p53 signaling pathway

Glioma

Fc epsilon RI signaling pathway

Thyroid cancer

mTOR signaling pathway

Endocytosis

Non-small cell lung cancer

Chronic myeloid leukemia

Neurotrophin signaling pathway

Type II diabetes mellitus

ErbB signaling pathway

Bladder cancer

Chemokine signaling pathway

Natural killer cell mediated cytotoxicity

Calcium signaling pathway

Renal cell carcinoma

Wnt signaling pathway

Small cell lung cancer

Cytokine-cytokine receptor interaction

Tight junction

Progesterone-mediated oocyte maturation

T cell receptor signaling pathway

Primary immunodeficiency

Neuroactive ligand-receptor interaction

Cell cycle

Apoptosis

Gap junction

Melanogenesis

Vascular smooth muscle contraction

GnRH signaling pathway

Homologous recombination

Long-term depression

Huntington's disease

Glycolysis / Gluconeogenesis

Adherens junction

Acute myeloid leukemia

Olfactory transduction

Starch and sucrose metabolism

Amino sugar and nucleotide sugar metabolism

VEGF signaling pathway

Leukocyte transendothelial migration

Long-term potentiation

Maturity onset diabetes of the young

Galactose metabolism

Jak-STAT signaling pathway

Axon guidance

Dorso-ventral axis formation

Fc gamma R-mediated phagocytosis

Basal cell carcinoma

Phosphatidylinositol signaling system

Amyotrophic lateral sclerosis (ALS)

Alzheimer's disease

Notch signaling pathway

Toll-like receptor signaling pathway

Dilated cardiomyopathy

Purine metabolism

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Inositol phosphate metabolism

Adipocytokine signaling pathway

Cell adhesion molecules (CAMs)

Oocyte meiosis

Hypertrophic cardiomyopathy (HCM)

Vibrio cholerae infection

Viral myocarditis

Lysosome

Epithelial cell signaling in Helicobacter pylori infection

ECM-receptor interaction

Taste transduction

Pyrimidine metabolism

Citrate cycle (TCA cycle)

Pathogenic Escherichia coli infection

Hematopoietic cell lineage

Parkinson's disease

Oxidative phosphorylation

PPAR signaling pathway

TGF-beta signaling pathway

Spliceosome

Cardiac muscle contraction

Nucleotide excision repair

Glycerophospholipid metabolism

NOD-like receptor signaling pathway

ABC transporters

Drug metabolism - cytochrome P450

RIG-I-like receptor signaling pathway

Metabolism of xenobiotics by cytochrome P450

Systemic lupus erythematosus

RNA degradation

Prion diseases

Glutathione metabolism

Retinol metabolism

Complement and coagulation cascades

Drug metabolism - other enzymes

Cytosolic DNA-sensing pathway

Arachidonic acid metabolism

N-Glycan biosynthesis

Lysine degradation

Arginine and proline metabolism

Ribosome

Tyrosine metabolism

Base excision repair

Antigen processing and presentation

Hedgehog signaling pathway

Pyruvate metabolism

Fatty acid metabolism

Glycerolipid metabolism

Sphingolipid metabolism

Cysteine and methionine metabolism

Autoimmune thyroid disease

Porphyrin and chlorophyll metabolism

Type I diabetes mellitus

Valine

DNA replication

Basal transcription factors

Tryptophan metabolism

RNA polymerase

Aminoacyl-tRNA biosynthesis

Proteasome

leucine and isoleucine degradation

Androgen and estrogen metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Pentose and glucuronate interconversions

Phenylalanine metabolism

Propanoate metabolism

Allograft rejection

Histidine metabolism

Fructose and mannose metabolism

Graft-versus-host disease

Nitrogen metabolism

Selenoamino acid metabolism

Ether lipid metabolism

Glycine

Steroid biosynthesis

serine and threonine metabolism

SNARE interactions in vesicular transport

Ascorbate and aldarate metabolism

Glycosaminoglycan degradation

Keratan sulfate biosynthesis

Alanine

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

One carbon pool by folate

aspartate and glutamate metabolism

Pantothenate and CoA biosynthesis

Pentose phosphate pathway

Nicotinate and nicotinamide metabolism

Chondroitin sulfate biosynthesis

Linoleic acid metabolism

Non-homologous end-joining

Regulation of autophagy

Biosynthesis of unsaturated fatty acids

Butanoate metabolism

Cyanoamino acid metabolism

Riboflavin metabolism

Circadian rhythm - mammal

Heparan sulfate biosynthesis

Primary bile acid biosynthesis

Protein export

Asthma

Glycosphingolipid biosynthesis - ganglio series

Other glycan degradation

beta-Alanine metabolism

Taurine and hypotaurine metabolism

Limonene and pinene degradation

O-Glycan biosynthesis

alpha-Linolenic acid metabolism

Glycosphingolipid biosynthesis - globo series

Glyoxylate and dicarboxylate metabolism

Renin-angiotensin system

Terpenoid backbone biosynthesis

Lysine biosynthesis

Thiamine metabolism

leucine and isoleucine biosynthesis

Fatty acid biosynthesis

Folate biosynthesis

O-Mannosyl glycan biosynthesis

Biotin metabolism

Sulfur metabolism

Lipoic acid metabolism

Methane metabolism

Phenylalanine

Synthesis and degradation of ketone bodies

tyrosine and tryptophan biosynthesis

Caffeine metabolism

D-Glutamine and D-glutamate metabolism

Fatty acid elongation in mitochondria

C21-Steroid hormone metabolism

Vitamin B6 metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Neomycin

None

1

Yes

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