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MEN1 Mutant (P12L), Myc-DDK-tagged ORF clone of Homo sapiens multiple endocrine neoplasia I (MEN1), transcript variant 2 as transfection-ready DNA
| Mutation | P12L |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
cDNA Clones
GPC3 Mutant (C65X), Myc-DDK-tagged ORF clone of Homo sapiens glypican 3 (GPC3), transcript variant 2 as transfection-ready DNA
| Mutation | C65X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
CSF1R Mutant (Y969C), Myc-DDK-tagged ORF clone of Homo sapiens colony stimulating factor 1 receptor (CSF1R) as transfection-ready DNA
| Mutation | Y969C |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MLH1 Mutant (Q62K), Myc-DDK-tagged ORF clone of Homo sapiens mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (MLH1), transcript variant 1 as transfection-ready DNA
| Mutation | Q62K |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
CTNNB1 Mutant (S33P), Myc-DDK-tagged ORF clone of Homo sapiens catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), transcript variant 1 as transfection-ready DNA
| Mutation | S33P |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
活动过滤器
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Species
Target Symbol
- CD44 (7)
- DNMT1 (6)
- FOXM1 (6)
- ISOCITRATE DEHYDROGENASE (6)
- KRAS (6)
- S PROTEIN (6)
- AKT1 (5)
- EGFR (5)
- MET (5)
- MLH1 (5)
- TRPA1 (5)
- ABCG2 (4)
- C9ORF72 (4)
- CHRNA3 (4)
- CREB1 (4)
- CXCR4 (4)
- CYP24A1 (4)
- DNMT3A (4)
- DUSP6 (4)
- FYN (4)
- MITF (4)
- MU OPIOID RECEPTOR (4)
- NRF1 (4)
- OLFM4 (4)
- P53 (4)
- P63 (4)
- PD-L1 (4)
- PTPRD (4)
- RHOT1 (4)
- SIRT1 (4)
- SLC22A24 (4)
- SOX6 (4)
- SPHK1 (4)
- STAT3 (4)
- TMEM16A (4)
- TXNIP (4)
- UCP2 (4)
- VEGFA (4)
- 5HT4 RECEPTOR (3)
- ACSL1 (3)
- ADAM17 (3)
- ADAM22 (3)
- ADAM23 (3)
- ADAR1 (3)
- AGTR1A (3)
- ALDH1A1 (3)
- ALDH1A3 (3)
- APOLIPOPROTEIN L 1 (3)
- ATG5 (3)
- B RAF (3)
- B7H3 (3)
- BIRC5 (3)
- BMPR2 (3)
- BRCA1 (3)
- BRG1 (3)
- CAMK2A (3)
- CAVEOLIN 1 (3)
- CDK4 (3)
- CEACAM1 (3)
- CERAMIDE SYNTHASE 2 (3)
- CHD4 (3)
- DUSP5 (3)
- ELAVL1 (3)
- FGFR2 (3)
- FGFR3 (3)
- FOXA2 (3)
- FOXO1 (3)
- FOXP3 (3)
- FRA1 (3)
- FSTL1 (3)
- GATA6 (3)
- GFAP (3)
- GLP1R (3)
- GLYPICAN 3 (3)
- GPBAR1 (3)
- GPR120 (3)
- GRIN1 (3)
- HDAC9 (3)
- HEPARANASE 1 (3)
- HER2 (3)
- HES1 (3)
- HIF-1 ALPHA (3)
- HMGB1 (3)
- HNF 4 ALPHA (3)
- IDH2 (3)
- IGFBP1 (3)
- IGFBP7 (3)
- IKZF1 (3)
- IRF1 (3)
- IRF9 (3)
- JMJD1C (3)
- KCNMA1 (3)
- LAMP2 (3)
- LRP5 (3)
- MC3R (3)
- MCL1 (3)
- MDM2 (3)
- MMP14 (3)
- MSR1 (3)
- NGF (3)
Vectors
Families
- Druggable Genome (1356)
- Transmembrane (762)
- Transcription Factors (350)
- Secreted Protein (153)
- ES Cell Differentiation/IPS (152)
- Protein Kinase (151)
- GPCR (97)
- Stem cell - Pluripotency (62)
- Protease (45)
- Adult stem cells (37)
- Embryonic stem cells (33)
- Ion Channels: Potassium (30)
- Nuclear Hormone Receptor (28)
- Cancer stem cells (25)
- Phosphatase (25)
- Ion Channels: Other (24)
- Induced pluripotent stem cells (18)
- Ion Channels: Transient receptor potential (17)
- Stem cell relevant signaling - DSL/Notch pathway (16)
- Ion Channels: Cys-loop Receptors (15)
- Stem cell relevant signaling - JAK/STAT signaling pathway (13)
- Ion Channels: Sodium (10)
- P450 (9)
- Ion Channels: Glutamate Receptors (6)
- Ion Channels: ATP Receptors (5)
- Ion Channels: Calcium (5)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (5)
- Stem cell relevant signaling - Wnt Signaling pathway (3)
Pathways
- Pathways in cancer (187)
- Metabolic pathways (151)
- MAPK signaling pathway (102)
- Focal adhesion (92)
- Neuroactive ligand-receptor interaction (89)
- Prostate cancer (81)
- Endocytosis (73)
- Cytokine-cytokine receptor interaction (71)
- Colorectal cancer (70)
- Chemokine signaling pathway (67)
- Melanoma (67)
- Regulation of actin cytoskeleton (66)
- Calcium signaling pathway (65)
- Neurotrophin signaling pathway (64)
- ErbB signaling pathway (63)
- Endometrial cancer (61)
- Glioma (60)
- Jak-STAT signaling pathway (58)
- Renal cell carcinoma (58)
- Axon guidance (56)
- Non-small cell lung cancer (56)
- Pancreatic cancer (56)
- Chronic myeloid leukemia (53)
- Insulin signaling pathway (53)
- T cell receptor signaling pathway (53)
- Natural killer cell mediated cytotoxicity (52)
- Wnt signaling pathway (50)
- Acute myeloid leukemia (48)
- Melanogenesis (48)
- VEGF signaling pathway (48)
- Bladder cancer (46)
- GnRH signaling pathway (43)
- Progesterone-mediated oocyte maturation (43)
- Gap junction (42)
- Toll-like receptor signaling pathway (42)
- Adherens junction (41)
- Apoptosis (41)
- B cell receptor signaling pathway (41)
- Fc epsilon RI signaling pathway (41)
- Cell adhesion molecules (CAMs) (40)
- Leukocyte transendothelial migration (40)
- Fc gamma R-mediated phagocytosis (39)
- Small cell lung cancer (39)
- Cell cycle (38)
- Alzheimer's disease (35)
- Tight junction (35)
- p53 signaling pathway (35)
- Long-term potentiation (34)
- Adipocytokine signaling pathway (33)
- Huntington's disease (33)
- Long-term depression (30)
- Thyroid cancer (30)
- Type II diabetes mellitus (30)
- Vascular smooth muscle contraction (30)
- mTOR signaling pathway (30)
- Epithelial cell signaling in Helicobacter pylori infection (29)
- Hematopoietic cell lineage (28)
- Purine metabolism (27)
- Basal cell carcinoma (26)
- TGF-beta signaling pathway (24)
- Oocyte meiosis (23)
- Notch signaling pathway (22)
- Phosphatidylinositol signaling system (22)
- Ubiquitin mediated proteolysis (22)
- Dorso-ventral axis formation (21)
- Glutathione metabolism (21)
- NOD-like receptor signaling pathway (21)
- Amyotrophic lateral sclerosis (ALS) (20)
- Lysosome (20)
- Prion diseases (20)
- RIG-I-like receptor signaling pathway (20)
- Pathogenic Escherichia coli infection (19)
- Viral myocarditis (19)
- ECM-receptor interaction (18)
- ABC transporters (17)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (17)
- Dilated cardiomyopathy (17)
- Hedgehog signaling pathway (17)
- Hypertrophic cardiomyopathy (HCM) (17)
- Inositol phosphate metabolism (17)
- PPAR signaling pathway (16)
- Parkinson's disease (15)
- Systemic lupus erythematosus (15)
- Cytosolic DNA-sensing pathway (14)
- Sphingolipid metabolism (14)
- Antigen processing and presentation (13)
- Arachidonic acid metabolism (13)
- Maturity onset diabetes of the young (13)
- Allograft rejection (12)
- Autoimmune thyroid disease (12)
- Pyrimidine metabolism (12)
- Type I diabetes mellitus (12)
- Citrate cycle (TCA cycle) (11)
- Complement and coagulation cascades (11)
- Fatty acid metabolism (11)
- Glycolysis / Gluconeogenesis (11)
- Graft-versus-host disease (11)
- Lysine degradation (11)
- Metabolism of xenobiotics by cytochrome P450 (11)
- Drug metabolism - cytochrome P450 (10)
- Glycerophospholipid metabolism (10)
- Pyruvate metabolism (10)
- Cysteine and methionine metabolism (9)
- Homologous recombination (9)
- Mismatch repair (9)
- Retinol metabolism (9)
- Spliceosome (9)
- Base excision repair (8)
- Glycerolipid metabolism (8)
- Primary immunodeficiency (8)
- Vibrio cholerae infection (8)
- Linoleic acid metabolism (7)
- Starch and sucrose metabolism (7)
- Tryptophan metabolism (7)
- Valine (7)
- Arginine and proline metabolism (6)
- Cardiac muscle contraction (6)
- Drug metabolism - other enzymes (6)
- Ether lipid metabolism (6)
- N-Glycan biosynthesis (6)
- Nicotinate and nicotinamide metabolism (6)
- RNA degradation (6)
- SNARE interactions in vesicular transport (6)
- Tyrosine metabolism (6)
- Asthma (5)
- Galactose metabolism (5)
- Nucleotide excision repair (5)
- Olfactory transduction (5)
- Oxidative phosphorylation (5)
- Regulation of autophagy (5)
- Ribosome (5)
- leucine and isoleucine degradation (5)
- Alanine (4)
- Biosynthesis of unsaturated fatty acids (4)
- DNA replication (4)
- Glycosaminoglycan degradation (4)
- Pantothenate and CoA biosynthesis (4)
- Propanoate metabolism (4)
- Renin-angiotensin system (4)
- Taste transduction (4)
- aspartate and glutamate metabolism (4)
- leucine and isoleucine biosynthesis (4)
- Butanoate metabolism (3)
- Fructose and mannose metabolism (3)
- Glycosphingolipid biosynthesis - ganglio series (3)
- Glycosphingolipid biosynthesis - lacto and neolacto series (3)
- Heparan sulfate biosynthesis (3)
- Pentose phosphate pathway (3)
- Phenylalanine metabolism (3)
- alpha-Linolenic acid metabolism (3)
- Amino sugar and nucleotide sugar metabolism (2)
- Aminoacyl-tRNA biosynthesis (2)
- Androgen and estrogen metabolism (2)
- C21-Steroid hormone metabolism (2)
- Circadian rhythm - mammal (2)
- D-Glutamine and D-glutamate metabolism (2)
- Folate biosynthesis (2)
- Glycine (2)
- Glycosphingolipid biosynthesis - globo series (2)
- Limonene and pinene degradation (2)
- Nitrogen metabolism (2)
- O-Glycan biosynthesis (2)
- Other glycan degradation (2)
- RNA polymerase (2)
- Synthesis and degradation of ketone bodies (2)
- Terpenoid backbone biosynthesis (2)
- serine and threonine metabolism (2)
- Caffeine metabolism (1)
- Chondroitin sulfate biosynthesis (1)
- Fatty acid biosynthesis (1)
- Histidine metabolism (1)
- Keratan sulfate biosynthesis (1)
- Lysine biosynthesis (1)
- Non-homologous end-joining (1)
- Porphyrin and chlorophyll metabolism (1)
- Primary bile acid biosynthesis (1)
- Proteasome (1)
- Riboflavin metabolism (1)
- Selenoamino acid metabolism (1)
- Steroid biosynthesis (1)
- Sulfur metabolism (1)
- Taurine and hypotaurine metabolism (1)
- beta-Alanine metabolism (1)
