cDNA Clones

cDNA Clones

Mutant ORF Clones

Expression Plasmids

Human

GCK

TSC2

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

BRAF

CBL

KRAS

HRAS

RAF1

NRAS

MAP2K2

B RAF

PRKACB

SORBS1

MAP2K1

P21 RAS

CBLB

EXOC7

SOCS2

ACAT1

PIK3R5

S6K1

HEXOKINASE 1

INSULIN

JNK2

MEK1

PI 3 KINASE P85 ALPHA

PKC ZETA

PROTEIN KINASE A REGULATORY SUBUNIT I ALPHA

A RAF

AKT1

AKT2

AKT3

AMPK GAMMA 1

CIP4

ELK1

GLUCOSE 6 PHOSPHATASE, CATALYTIC SUBUNIT

IKK BETA

JNK1

JNK3

LAR

PDPK1

PHKG1

PI 3 KINASE CATALYTIC SUBUNIT GAMMA

PI 3 KINASE P55 GAMMA

PIK3CB

SHC

SOCS4

TUBERIN

ACACB

CALMODULIN

ERK2

FATTY ACID SYNTHASE

G6PC2

GLUCOKINASE

GRF2

INSULIN RECEPTOR

IRS1

MNK1

PDE3A

PGC1 ALPHA

PHKA1

PI 3 KINASE P85 BETA

PIK3CA

PP1C GAMMA

PPP1A

PPP1R3B

PPP1R3D

PRKACA

PRKAG2

PTP1B

PYGL

PYRUVATE KINASE

SHIP

SOCS3

SOS1

SREBP1

Myc-DDK

pCMV6-Entry

pCMV6-AC-GFP

pCMV6-XL5-DDK-His

Yes

No

TrueORF

TrueORF Gold, TrueORF

TrueClone

Druggable Genome

Protein Kinase

Transcription Factors

ES Cell Differentiation/IPS

Transmembrane

Phosphatase

Secreted Protein

Pathways in cancer

Colorectal cancer

Insulin signaling pathway

Metabolic pathways

Endometrial cancer

Pancreatic cancer

MAPK signaling pathway

Focal adhesion

Ubiquitin mediated proteolysis

Mismatch repair

B cell receptor signaling pathway

Fc epsilon RI signaling pathway

Prostate cancer

Regulation of actin cytoskeleton

mTOR signaling pathway

Melanoma

Type II diabetes mellitus

ErbB signaling pathway

Glioma

p53 signaling pathway

Endocytosis

Thyroid cancer

Chemokine signaling pathway

Renal cell carcinoma

Non-small cell lung cancer

Calcium signaling pathway

Natural killer cell mediated cytotoxicity

Chronic myeloid leukemia

Cytokine-cytokine receptor interaction

Neurotrophin signaling pathway

Progesterone-mediated oocyte maturation

T cell receptor signaling pathway

Primary immunodeficiency

Gap junction

Neuroactive ligand-receptor interaction

Melanogenesis

Bladder cancer

GnRH signaling pathway

Long-term depression

Homologous recombination

Glycolysis / Gluconeogenesis

VEGF signaling pathway

Vascular smooth muscle contraction

Acute myeloid leukemia

Adherens junction

Starch and sucrose metabolism

Maturity onset diabetes of the young

Long-term potentiation

Tight junction

Galactose metabolism

Amino sugar and nucleotide sugar metabolism

Jak-STAT signaling pathway

Leukocyte transendothelial migration

Dorso-ventral axis formation

Small cell lung cancer

Wnt signaling pathway

Axon guidance

Phosphatidylinositol signaling system

Fc gamma R-mediated phagocytosis

Apoptosis

Toll-like receptor signaling pathway

Notch signaling pathway

Cell cycle

Dilated cardiomyopathy

Inositol phosphate metabolism

Adipocytokine signaling pathway

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Alzheimer's disease

Oocyte meiosis

Purine metabolism

Cell adhesion molecules (CAMs)

Basal cell carcinoma

Taste transduction

Hypertrophic cardiomyopathy (HCM)

Vibrio cholerae infection

Hematopoietic cell lineage

Olfactory transduction

Epithelial cell signaling in Helicobacter pylori infection

ECM-receptor interaction

Pathogenic Escherichia coli infection

Huntington's disease

Amyotrophic lateral sclerosis (ALS)

Citrate cycle (TCA cycle)

PPAR signaling pathway

TGF-beta signaling pathway

NOD-like receptor signaling pathway

Viral myocarditis

ABC transporters

Lysosome

Nucleotide excision repair

Cardiac muscle contraction

Prion diseases

Complement and coagulation cascades

RIG-I-like receptor signaling pathway

Pyrimidine metabolism

Glycerophospholipid metabolism

Arachidonic acid metabolism

Base excision repair

Hedgehog signaling pathway

Drug metabolism - cytochrome P450

Retinol metabolism

Metabolism of xenobiotics by cytochrome P450

Tyrosine metabolism

Parkinson's disease

Arginine and proline metabolism

Lysine degradation

Cytosolic DNA-sensing pathway

Drug metabolism - other enzymes

Cysteine and methionine metabolism

Fatty acid metabolism

Glycerolipid metabolism

Systemic lupus erythematosus

Valine

Autoimmune thyroid disease

Glutathione metabolism

Pyruvate metabolism

Histidine metabolism

Type I diabetes mellitus

leucine and isoleucine degradation

Antigen processing and presentation

Sphingolipid metabolism

Tryptophan metabolism

Propanoate metabolism

Nitrogen metabolism

Phenylalanine metabolism

Steroid biosynthesis

Allograft rejection

SNARE interactions in vesicular transport

Fructose and mannose metabolism

Aminoacyl-tRNA biosynthesis

Non-homologous end-joining

Proteasome

Riboflavin metabolism

DNA replication

Oxidative phosphorylation

Androgen and estrogen metabolism

Circadian rhythm - mammal

Graft-versus-host disease

Linoleic acid metabolism

Selenoamino acid metabolism

Alanine

Butanoate metabolism

Pentose phosphate pathway

Spliceosome

aspartate and glutamate metabolism

Ether lipid metabolism

Renin-angiotensin system

Glycine

Glycosaminoglycan degradation

Other glycan degradation

Porphyrin and chlorophyll metabolism

Primary bile acid biosynthesis

serine and threonine metabolism

N-Glycan biosynthesis

Regulation of autophagy

beta-Alanine metabolism

Fatty acid biosynthesis

One carbon pool by folate

Pantothenate and CoA biosynthesis

Protein export

RNA degradation

Terpenoid backbone biosynthesis

leucine and isoleucine biosynthesis

Ascorbate and aldarate metabolism

Asthma

Glycosphingolipid biosynthesis - ganglio series

Nicotinate and nicotinamide metabolism

Pentose and glucuronate interconversions

Basal transcription factors

Folate biosynthesis

Limonene and pinene degradation

alpha-Linolenic acid metabolism

Biotin metabolism

Glyoxylate and dicarboxylate metabolism

Ribosome

Synthesis and degradation of ketone bodies

Taurine and hypotaurine metabolism

Thiamine metabolism

Biosynthesis of unsaturated fatty acids

C21-Steroid hormone metabolism

Phenylalanine

tyrosine and tryptophan biosynthesis

Caffeine metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Heparan sulfate biosynthesis

Chondroitin sulfate biosynthesis

Fatty acid elongation in mitochondria

Glycosphingolipid biosynthesis - globo series

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Lysine biosynthesis

Neomycin

1

Yes

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