cDNA Clones

cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

GLUCOCORTICOID RECEPTOR

MU OPIOID RECEPTOR

PTGER3

LPAR6

METABOTROPIC GLUTAMATE RECEPTOR 4

LGR7

METABOTROPIC GLUTAMATE RECEPTOR 1

CANNABINOID RECEPTOR I

GRIA1

GROWTH HORMONE RECEPTOR

P2Y6

PROLACTIN RECEPTOR

VIP RECEPTOR 1

5HT4 RECEPTOR

ADENOSINE RECEPTOR A2A

ALPHA 1A ADRENERGIC RECEPTOR

CORTICOTROPIN RELEASING FACTOR RECEPTOR 2

CRF1

DOPAMINE RECEPTOR D3

GABRR1

GRIA4

LEPTIN RECEPTOR

P2RX4

PACAP RECEPTOR

5HT7 RECEPTOR

ANGIOTENSIN II TYPE 1 RECEPTOR

CYSLT1

GABA A RECEPTOR ALPHA 4

GABA A RECEPTOR BETA 3

GLUR3

GPR35

GROWTH HORMONE

NMDAR1

NMDAR2A

NPFFR2

P2RY5

P2X2

P2X5

THYROID HORMONE RECEPTOR ALPHA

ADENOSINE A3 RECEPTOR

ALPHA 1 GLYCINE RECEPTOR

CRLR

FPR1

FSH RECEPTOR

GABA A RECEPTOR GAMMA 2

GABA B RECEPTOR 1

GABRP

GLRB

GPR58

GRIK5

HRH1

HRH4

HTR2C

IONOTROPIC GLUTAMATE RECEPTOR 2

KA1

MCH2

PBR

PROSTAGLANDIN D2 RECEPTOR

SOMATOSTATIN RECEPTOR 5

TRYPSIN

TSH RECEPTOR

5 HT 2A

5 HT1F

ADENOSINE A1 RECEPTOR

ALPHA 1D ADRENERGIC RECEPTOR

ALPHA 2B ADRENERGIC RECEPTOR

AVPR V2

BDKRB1

BDKRB2

BETA 1 ADRENERGIC RECEPTOR

BOMBESIN RECEPTOR 3

CALCITONIN RECEPTOR

CATHEPSIN G

CCKBR

DOPAMINE D2 RECEPTOR

DOPAMINE RECEPTOR D4

EDG1

EDG8

ENDOTHELIN A RECEPTOR

ENDOTHELIN B RECEPTOR

EP1

EP4

FPR3

FPRL1

GABA A RECEPTOR ALPHA 6

GABA A RECEPTOR DELTA

GABRA2

GABRE

GABRG3

GABRR2

GALR2

GH2

GHRELIN RECEPTOR

GHRHR

GLP2R

GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2D

GLYCINE RECEPTOR ALPHA 3

GNRHR

GPR102

GPR14

Myc-DDK

pCMV6-AC-GFP

pCMV6-Entry

pCMV6-AC-Myc-DDK

No

Yes

TrueORF

TrueORF Gold, TrueORF

TrueClone

Druggable Genome

Transmembrane

GPCR

Ion Channels: Glutamate Receptors

Ion Channels: Cys-loop Receptors

Transcription Factors

Nuclear Hormone Receptor

Secreted Protein

Ion Channels: ATP Receptors

ES Cell Differentiation/IPS

Protease

Ion Channels: Sodium

Ion Channels: Transient receptor potential

Pathways in cancer

Colorectal cancer

Insulin signaling pathway

Metabolic pathways

Endometrial cancer

Pancreatic cancer

MAPK signaling pathway

Focal adhesion

Ubiquitin mediated proteolysis

Mismatch repair

B cell receptor signaling pathway

Fc epsilon RI signaling pathway

Prostate cancer

Regulation of actin cytoskeleton

mTOR signaling pathway

Melanoma

Type II diabetes mellitus

ErbB signaling pathway

Glioma

p53 signaling pathway

Endocytosis

Thyroid cancer

Chemokine signaling pathway

Non-small cell lung cancer

Renal cell carcinoma

Calcium signaling pathway

Chronic myeloid leukemia

Natural killer cell mediated cytotoxicity

Cytokine-cytokine receptor interaction

Neurotrophin signaling pathway

Progesterone-mediated oocyte maturation

T cell receptor signaling pathway

Primary immunodeficiency

Gap junction

Neuroactive ligand-receptor interaction

Bladder cancer

Melanogenesis

Long-term depression

GnRH signaling pathway

Homologous recombination

Glycolysis / Gluconeogenesis

VEGF signaling pathway

Acute myeloid leukemia

Vascular smooth muscle contraction

Adherens junction

Starch and sucrose metabolism

Maturity onset diabetes of the young

Tight junction

Galactose metabolism

Long-term potentiation

Amino sugar and nucleotide sugar metabolism

Jak-STAT signaling pathway

Leukocyte transendothelial migration

Dorso-ventral axis formation

Small cell lung cancer

Wnt signaling pathway

Axon guidance

Phosphatidylinositol signaling system

Fc gamma R-mediated phagocytosis

Apoptosis

Toll-like receptor signaling pathway

Notch signaling pathway

Cell cycle

Dilated cardiomyopathy

Inositol phosphate metabolism

Adipocytokine signaling pathway

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Alzheimer's disease

Oocyte meiosis

Purine metabolism

Cell adhesion molecules (CAMs)

Basal cell carcinoma

Hypertrophic cardiomyopathy (HCM)

Taste transduction

Vibrio cholerae infection

Epithelial cell signaling in Helicobacter pylori infection

Hematopoietic cell lineage

Olfactory transduction

ECM-receptor interaction

Pathogenic Escherichia coli infection

Huntington's disease

Amyotrophic lateral sclerosis (ALS)

Citrate cycle (TCA cycle)

TGF-beta signaling pathway

PPAR signaling pathway

NOD-like receptor signaling pathway

Viral myocarditis

ABC transporters

Lysosome

Nucleotide excision repair

Cardiac muscle contraction

Complement and coagulation cascades

Prion diseases

RIG-I-like receptor signaling pathway

Pyrimidine metabolism

Glycerophospholipid metabolism

Arachidonic acid metabolism

Base excision repair

Drug metabolism - cytochrome P450

Hedgehog signaling pathway

Retinol metabolism

Metabolism of xenobiotics by cytochrome P450

Tyrosine metabolism

Arginine and proline metabolism

Lysine degradation

Parkinson's disease

Cytosolic DNA-sensing pathway

Drug metabolism - other enzymes

Cysteine and methionine metabolism

Fatty acid metabolism

Glycerolipid metabolism

Systemic lupus erythematosus

Valine

Glutathione metabolism

Autoimmune thyroid disease

Pyruvate metabolism

Histidine metabolism

Type I diabetes mellitus

leucine and isoleucine degradation

Antigen processing and presentation

Sphingolipid metabolism

Tryptophan metabolism

Propanoate metabolism

Nitrogen metabolism

Phenylalanine metabolism

Steroid biosynthesis

Allograft rejection

SNARE interactions in vesicular transport

Fructose and mannose metabolism

Aminoacyl-tRNA biosynthesis

Non-homologous end-joining

Proteasome

Oxidative phosphorylation

Circadian rhythm - mammal

DNA replication

Riboflavin metabolism

Androgen and estrogen metabolism

Graft-versus-host disease

Linoleic acid metabolism

Selenoamino acid metabolism

Alanine

Butanoate metabolism

Pentose phosphate pathway

Spliceosome

aspartate and glutamate metabolism

Ether lipid metabolism

Renin-angiotensin system

Glycine

Glycosaminoglycan degradation

Other glycan degradation

Porphyrin and chlorophyll metabolism

Primary bile acid biosynthesis

serine and threonine metabolism

N-Glycan biosynthesis

Regulation of autophagy

beta-Alanine metabolism

Fatty acid biosynthesis

One carbon pool by folate

Protein export

RNA degradation

Terpenoid backbone biosynthesis

leucine and isoleucine biosynthesis

Ascorbate and aldarate metabolism

Asthma

Glycosphingolipid biosynthesis - ganglio series

Nicotinate and nicotinamide metabolism

Pantothenate and CoA biosynthesis

Pentose and glucuronate interconversions

Basal transcription factors

Folate biosynthesis

Limonene and pinene degradation

alpha-Linolenic acid metabolism

Biotin metabolism

Glyoxylate and dicarboxylate metabolism

Ribosome

Synthesis and degradation of ketone bodies

Taurine and hypotaurine metabolism

Thiamine metabolism

Biosynthesis of unsaturated fatty acids

C21-Steroid hormone metabolism

Phenylalanine

tyrosine and tryptophan biosynthesis

Caffeine metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Heparan sulfate biosynthesis

Chondroitin sulfate biosynthesis

Fatty acid elongation in mitochondria

Glycosphingolipid biosynthesis - globo series

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Lysine biosynthesis

Neomycin

1

Yes

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