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BRCA2 Mutant (E1876X), Myc-DDK-tagged ORF clone of Homo sapiens breast Cancer, early onset (BRCA2) as transfection-ready DNA
| Mutation | E1876X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
cDNA Clones
NRAS mutant (G13C), Myc-DDK-tagged ORF clone of Homo sapiens neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS) as transfection-ready DNA
| Mutation | G13C |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
ERCC2 Mutant (R378H), Myc-DDK-tagged ORF clone of Homo sapiens excision repair cross-complementing rodent repair deficiency, complementation group 2 (ERCC2), transcript variant 1 as transfection-ready DNA
| Mutation | R378H |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
BRCA2 Mutant (S2186X), Myc-DDK-tagged ORF clone of Homo sapiens breast Cancer, early onset (BRCA2) as transfection-ready DNA
| Mutation | S2186X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
BRCA2 Mutant (K1872X), Myc-DDK-tagged ORF clone of Homo sapiens breast Cancer, early onset (BRCA2) as transfection-ready DNA
| Mutation | K1872X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
NOTCH3 Mutant (R90C), Myc-DDK-tagged ORF clone of Homo sapiens notch 3 (NOTCH3) as transfection-ready DNA
| Mutation | R90C |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MSH2 Mutant (L175P), Myc-DDK-tagged ORF clone of Homo sapiens mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) (MSH2) as transfection-ready DNA
| Mutation | L175P |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MSH2 Mutant (A870G), Myc-DDK-tagged ORF clone of Homo sapiens mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) (MSH2) as transfection-ready DNA
| Mutation | A870G |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
TSC2 Mutant (A1164V), Myc-DDK-tagged ORF clone of Homo sapiens tuberous sclerosis 2 (TSC2), transcript variant 1 as transfection-ready DNA
| Mutation | A1164V |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
BRCA2 Mutant (N924I), Myc-DDK-tagged ORF clone of Homo sapiens breast Cancer, early onset (BRCA2) as transfection-ready DNA
| Mutation | N924I |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
PTEN Mutant (R159K), Myc-DDK-tagged ORF clone of Homo sapiens phosphatase and tensin homolog (PTEN) as transfection-ready DNA
| Mutation | R159K |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
FH Mutant (S187L), Myc-DDK-tagged ORF clone of Homo sapiens fumarate hydratase (FH), nuclear gene encoding mitochondrial protein as transfection-ready DNA
| Mutation | S187L |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
STK11 Mutant (V66M), Myc-DDK-tagged ORF clone of Homo sapiens serine/threonine kinase 11 (STK11) as transfection-ready DNA
| Mutation | V66M |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
TSC2 Mutant (R751X), Myc-DDK-tagged ORF clone of Homo sapiens tuberous sclerosis 2 (TSC2), transcript variant 1 as transfection-ready DNA
| Mutation | R751X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
BTK Mutant (I61T), Myc-DDK-tagged ORF clone of Homo sapiens Bruton agammaglobulinemia tyrosine kinase (BTK) as transfection-ready DNA
| Mutation | I61T |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
活动过滤器
优化搜索结果
Species
Target Symbol
- BRCA1 (401)
- BTK (299)
- BRCA2 (279)
- GLUCOKINASE (252)
- MLH1 (250)
- MENIN (249)
- TUBERIN (245)
- MSH2 (218)
- RET (188)
- NOTCH3 (160)
- P53 (148)
- NF2 (110)
- MSH6 (93)
- CREM (83)
- LKB1 (83)
- FGFR1 (80)
- WILMS TUMOR PROTEIN (72)
- PI 3 KINASE CATALYTIC SUBUNIT ALPHA (69)
- CACNA1G (65)
- VEGFA (64)
- FH (62)
- E4 (61)
- CACNA1C (60)
- L2 (60)
- G PROTEIN ALPHA S (58)
- EGFR (54)
- CTNND1 (53)
- PCDH15 (52)
- UTY (52)
- L1 (50)
- BETA CATENIN (49)
- IKAROS (47)
- PTEN (47)
- B RAF (45)
- DISC1 (45)
- NRG1 (45)
- TPM1 (44)
- KCNMA1 (42)
- FLT4 (41)
- BDNF (40)
- PLAGL1 (40)
- E3 (39)
- ST3GAL3 (39)
- XPD (39)
- UBE2V1 (37)
- EMA (36)
- HMGA1 (36)
- PRKCBP1 (36)
- TCF7L2 (36)
- TNNT3 (36)
- TRPM3 (36)
- BIM (35)
- E1 (35)
- PDLIM5 (35)
- RUNX1T1 (35)
- KCNQ2 (34)
- PDE9A (34)
- SORBS1 (34)
- SYTL2 (34)
- TELOMERASE REVERSE TRANSCRIPTASE (34)
- ARPP21 (33)
- ANKS1B (32)
- BORIS (32)
- E6 (32)
- E7 (32)
- FGFR2 (32)
- IKZF3 (32)
- MU OPIOID RECEPTOR (32)
- ZNF83 (32)
- DYSTROPHIN (31)
- E2 (31)
- ODF2 (31)
- PRKACB (31)
- ESTROGEN RELATED RECEPTOR GAMMA (30)
- IFI27 (30)
- KCNJ15 (30)
- MIER1 (30)
- MORTALITY FACTOR 4 LIKE 2 (30)
- PARD3 (30)
- ZNF133 (30)
- LDB3 (29)
- MYADM (29)
- P16INK4A (29)
- SYNTABULIN (29)
- TCF4 (29)
- ATP2C1 (28)
- DYSFERLIN (28)
- DYSTROBREVIN ALPHA (28)
- FGF1 (28)
- GLUCOCORTICOID RECEPTOR (28)
- NDRG2 (28)
- TPD52 (28)
- ZNF302 (28)
- ARFRP1 (27)
- CBL (27)
- CHIMAERIN 2 (27)
- EDA (27)
- MBD1 (27)
- P21 RAS (27)
- PAK3 (27)
Vectors
Mutants
Families
- Druggable Genome (26840)
- Transmembrane (15544)
- Transcription Factors (7816)
- Secreted Protein (3565)
- Protein Kinase (2778)
- Stem cell - Pluripotency (1452)
- Protease (1299)
- ES Cell Differentiation/IPS (1254)
- GPCR (917)
- Phosphatase (636)
- Ion Channels: Other (421)
- Nuclear Hormone Receptor (319)
- Adult stem cells (285)
- Ion Channels: Potassium (235)
- Embryonic stem cells (214)
- Cancer stem cells (158)
- Ion Channels: Cys-loop Receptors (147)
- Ion Channels: Calcium (139)
- P450 (114)
- Induced pluripotent stem cells (111)
- Ion Channels: Transient receptor potential (110)
- Stem cell relevant signaling - JAK/STAT signaling pathway (106)
- Ion Channels: Glutamate Receptors (77)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (63)
- Stem cell relevant signaling - DSL/Notch pathway (60)
- Ion Channels: Sodium (57)
- Stem cell relevant signaling - Wnt Signaling pathway (49)
- Ion Channels: ATP Receptors (33)
- Ion Channels: Cyclic nucleotide gated (23)
Pathways
- Metabolic pathways (3549)
- Pathways in cancer (2991)
- MAPK signaling pathway (1512)
- Colorectal cancer (1243)
- Insulin signaling pathway (1182)
- Regulation of actin cytoskeleton (1092)
- Focal adhesion (1083)
- Endometrial cancer (962)
- Ubiquitin mediated proteolysis (962)
- Endocytosis (955)
- Pancreatic cancer (937)
- Cytokine-cytokine receptor interaction (913)
- Prostate cancer (911)
- Neuroactive ligand-receptor interaction (910)
- Calcium signaling pathway (852)
- Neurotrophin signaling pathway (827)
- Chemokine signaling pathway (812)
- Melanoma (811)
- p53 signaling pathway (761)
- Olfactory transduction (741)
- Wnt signaling pathway (741)
- B cell receptor signaling pathway (740)
- Glioma (707)
- Huntington's disease (687)
- Fc epsilon RI signaling pathway (686)
- Natural killer cell mediated cytotoxicity (685)
- ErbB signaling pathway (673)
- Tight junction (669)
- Progesterone-mediated oocyte maturation (667)
- Chronic myeloid leukemia (666)
- mTOR signaling pathway (663)
- Non-small cell lung cancer (643)
- Cell cycle (628)
- Thyroid cancer (628)
- Mismatch repair (622)
- T cell receptor signaling pathway (604)
- Type II diabetes mellitus (604)
- Axon guidance (598)
- Jak-STAT signaling pathway (592)
- Leukocyte transendothelial migration (588)
- Vascular smooth muscle contraction (586)
- Purine metabolism (583)
- Alzheimer's disease (579)
- Apoptosis (579)
- Small cell lung cancer (575)
- Renal cell carcinoma (562)
- Adherens junction (559)
- Bladder cancer (558)
- GnRH signaling pathway (556)
- Melanogenesis (544)
- Gap junction (531)
- VEGF signaling pathway (498)
- Long-term depression (482)
- Acute myeloid leukemia (476)
- Fc gamma R-mediated phagocytosis (470)
- Long-term potentiation (462)
- Dilated cardiomyopathy (452)
- Glycolysis / Gluconeogenesis (444)
- Cell adhesion molecules (CAMs) (439)
- Oocyte meiosis (436)
- Primary immunodeficiency (419)
- Toll-like receptor signaling pathway (419)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (410)
- Amino sugar and nucleotide sugar metabolism (399)
- Starch and sucrose metabolism (397)
- Lysosome (384)
- Phosphatidylinositol signaling system (375)
- Homologous recombination (373)
- Hypertrophic cardiomyopathy (HCM) (361)
- Amyotrophic lateral sclerosis (ALS) (353)
- Basal cell carcinoma (348)
- Adipocytokine signaling pathway (334)
- Pyrimidine metabolism (334)
- Galactose metabolism (327)
- Maturity onset diabetes of the young (327)
- Hematopoietic cell lineage (321)
- Parkinson's disease (311)
- Viral myocarditis (311)
- Dorso-ventral axis formation (306)
- Oxidative phosphorylation (301)
- Spliceosome (299)
- Notch signaling pathway (294)
- Inositol phosphate metabolism (290)
- ECM-receptor interaction (283)
- PPAR signaling pathway (275)
- Systemic lupus erythematosus (266)
- Epithelial cell signaling in Helicobacter pylori infection (254)
- Cardiac muscle contraction (248)
- TGF-beta signaling pathway (247)
- Vibrio cholerae infection (240)
- Glycerophospholipid metabolism (230)
- NOD-like receptor signaling pathway (230)
- Pathogenic Escherichia coli infection (226)
- RIG-I-like receptor signaling pathway (220)
- Drug metabolism - cytochrome P450 (213)
- Taste transduction (209)
- Antigen processing and presentation (208)
- Metabolism of xenobiotics by cytochrome P450 (204)
- Complement and coagulation cascades (201)
- Ribosome (194)
- RNA degradation (184)
- Glutathione metabolism (181)
- Cytosolic DNA-sensing pathway (173)
- Citrate cycle (TCA cycle) (171)
- Arachidonic acid metabolism (170)
- Drug metabolism - other enzymes (169)
- Nucleotide excision repair (169)
- Retinol metabolism (168)
- Arginine and proline metabolism (166)
- ABC transporters (159)
- Hedgehog signaling pathway (153)
- N-Glycan biosynthesis (147)
- Tyrosine metabolism (145)
- Lysine degradation (141)
- Valine (141)
- Prion diseases (140)
- Pyruvate metabolism (139)
- Fatty acid metabolism (136)
- Base excision repair (133)
- Glycerolipid metabolism (132)
- Sphingolipid metabolism (123)
- Autoimmune thyroid disease (122)
- leucine and isoleucine degradation (120)
- Cysteine and methionine metabolism (117)
- Proteasome (116)
- Type I diabetes mellitus (114)
- Tryptophan metabolism (110)
- Porphyrin and chlorophyll metabolism (108)
- DNA replication (104)
- Aminoacyl-tRNA biosynthesis (98)
- Glycosphingolipid biosynthesis - lacto and neolacto series (97)
- Androgen and estrogen metabolism (96)
- Propanoate metabolism (96)
- Basal transcription factors (95)
- Fructose and mannose metabolism (94)
- Graft-versus-host disease (93)
- SNARE interactions in vesicular transport (92)
- RNA polymerase (90)
- Allograft rejection (89)
- Histidine metabolism (88)
- Ether lipid metabolism (87)
- Alanine (86)
- aspartate and glutamate metabolism (86)
- Selenoamino acid metabolism (85)
- Glycine (82)
- serine and threonine metabolism (82)
- Nitrogen metabolism (81)
- Phenylalanine metabolism (81)
- Pentose phosphate pathway (79)
- Pentose and glucuronate interconversions (77)
- Butanoate metabolism (74)
- Glycosaminoglycan degradation (72)
- Regulation of autophagy (72)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (66)
- Linoleic acid metabolism (65)
- Keratan sulfate biosynthesis (64)
- Nicotinate and nicotinamide metabolism (64)
- Steroid biosynthesis (64)
- Pantothenate and CoA biosynthesis (63)
- Ascorbate and aldarate metabolism (62)
- One carbon pool by folate (61)
- O-Glycan biosynthesis (58)
- Asthma (57)
- Biosynthesis of unsaturated fatty acids (55)
- beta-Alanine metabolism (55)
- Heparan sulfate biosynthesis (54)
- Chondroitin sulfate biosynthesis (53)
- Primary bile acid biosynthesis (53)
- Riboflavin metabolism (53)
- Non-homologous end-joining (49)
- Other glycan degradation (47)
- Glycosphingolipid biosynthesis - ganglio series (44)
- alpha-Linolenic acid metabolism (44)
- Cyanoamino acid metabolism (43)
- Circadian rhythm - mammal (41)
- Glycosphingolipid biosynthesis - globo series (41)
- Taurine and hypotaurine metabolism (41)
- Glyoxylate and dicarboxylate metabolism (40)
- Limonene and pinene degradation (40)
- Protein export (40)
- Renin-angiotensin system (40)
- Terpenoid backbone biosynthesis (40)
- Sulfur metabolism (38)
- leucine and isoleucine biosynthesis (33)
- Thiamine metabolism (28)
- Folate biosynthesis (27)
- C21-Steroid hormone metabolism (22)
- Caffeine metabolism (21)
- Synthesis and degradation of ketone bodies (21)
- Fatty acid biosynthesis (20)
- Fatty acid elongation in mitochondria (20)
- Lysine biosynthesis (20)
- Methane metabolism (17)
- O-Mannosyl glycan biosynthesis (17)
- Lipoic acid metabolism (16)
- Biotin metabolism (14)
- Phenylalanine (14)
- tyrosine and tryptophan biosynthesis (14)
- D-Glutamine and D-glutamate metabolism (12)
- Ubiquinone and other terpenoid-quinone biosynthesis (11)
- Vitamin B6 metabolism (8)
- D-Arginine and D-ornithine metabolism (1)
