cDNA Clones

cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

P53

CHK2

CDK1

CHK1

PIRH2

CASPASE 9

GADD45A

CYCLIN E1

CYCLIN B1

CYCLIN D1

NOXA

CYCLIN B2

RCHY1

TP53

Plasmids

Myc-DDK

Tag Free

TurboGFP

mGFP

pCMV6-AC-Myc-DDK

pCMV6-Entry

pCMV6-AC-GFP

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP-P2A-Puro

pCMV6-AN-Myc-DDK

pCMV6-XL5

pLenti-C-Myc-DDK

pLenti-C-mGFP

pCMV6-XL4

PCMV6-Neo

pCMV6-AC

No

Yes

TrueORF

LentiORF

TrueClone

TrueORF Gold, TrueORF

Druggable Genome

Stem cell - Pluripotency

Transcription Factors

Transmembrane

Protein Kinase

Secreted Protein

Protease

ES Cell Differentiation/IPS

Phosphatase

Stem cell relevant signaling - DSL/Notch pathway

Stem cell relevant signaling - JAK/STAT signaling pathway

Stem cell relevant signaling - Wnt Signaling pathway

Pathways in cancer

Colorectal cancer

Cell cycle

Mismatch repair

p53 signaling pathway

MAPK signaling pathway

Small cell lung cancer

Prostate cancer

Metabolic pathways

Amyotrophic lateral sclerosis (ALS)

Chronic myeloid leukemia

Huntington's disease

Pancreatic cancer

Apoptosis

Wnt signaling pathway

Endometrial cancer

Neurotrophin signaling pathway

Non-small cell lung cancer

Bladder cancer

Thyroid cancer

Glioma

Melanoma

Basal cell carcinoma

DNA replication

Spliceosome

Nucleotide excision repair

Base excision repair

Homologous recombination

Focal adhesion

Oocyte meiosis

RNA degradation

Purine metabolism

T cell receptor signaling pathway

Regulation of actin cytoskeleton

Pyrimidine metabolism

Progesterone-mediated oocyte maturation

ErbB signaling pathway

Jak-STAT signaling pathway

Antigen processing and presentation

Proteasome

Axon guidance

Endocytosis

Prion diseases

Chemokine signaling pathway

Ubiquitin mediated proteolysis

Renal cell carcinoma

Natural killer cell mediated cytotoxicity

Viral myocarditis

Cytosolic DNA-sensing pathway

Cysteine and methionine metabolism

Notch signaling pathway

Systemic lupus erythematosus

VEGF signaling pathway

Alzheimer's disease

B cell receptor signaling pathway

Fc gamma R-mediated phagocytosis

NOD-like receptor signaling pathway

Gap junction

Acute myeloid leukemia

Glycerophospholipid metabolism

Cytokine-cytokine receptor interaction

Non-homologous end-joining

Drug metabolism - other enzymes

Leukocyte transendothelial migration

RNA polymerase

One carbon pool by folate

Primary immunodeficiency

TGF-beta signaling pathway

ECM-receptor interaction

Parkinson's disease

Calcium signaling pathway

Adherens junction

Insulin signaling pathway

SNARE interactions in vesicular transport

Pathogenic Escherichia coli infection

Adipocytokine signaling pathway

Ether lipid metabolism

Glycerolipid metabolism

RIG-I-like receptor signaling pathway

Sphingolipid metabolism

Hematopoietic cell lineage

Melanogenesis

Type I diabetes mellitus

Folate biosynthesis

Fructose and mannose metabolism

Glycolysis / Gluconeogenesis

Pentose phosphate pathway

Selenoamino acid metabolism

Epithelial cell signaling in Helicobacter pylori infection

Alanine

Arginine and proline metabolism

Phenylalanine

Phenylalanine metabolism

Tyrosine metabolism

aspartate and glutamate metabolism

tyrosine and tryptophan biosynthesis

Basal transcription factors

Glycine

serine and threonine metabolism

Cardiac muscle contraction

Dilated cardiomyopathy

Hypertrophic cardiomyopathy (HCM)

Steroid biosynthesis

Type II diabetes mellitus

Nicotinate and nicotinamide metabolism

Glyoxylate and dicarboxylate metabolism

Neomycin

Puromycin

None

1

Yes

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