cDNA Clones

cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

FH

ISOCITRATE DEHYDROGENASE

SDHC

MDH1

PDHA1

IDH2

OGDH

OGDHL

PCB

ATP CITRATE LYASE

LIPOAMIDE DEHYDROGENASE

PCK2

SDHD

IDH3B

IDH3G

MDH2

SUCLG2

ACONITASE 1

DLST

PDHB

SDHA

ACONITASE 2

CITRATE SYNTHETASE

IDH3A

PCK1

PYRUVATE DEHYDROGENASE E2

SDHB

PDHA2

SUCLA2

SUCLG1

Plasmids

Myc-DDK

mGFP

Tag Free

TurboGFP

pCMV6-Entry

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-Myc-DDK

No

Yes

TrueORF

LentiORF

TrueORF Gold, TrueORF

Druggable Genome

Transmembrane

ES Cell Differentiation/IPS

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Regulation of actin cytoskeleton

Insulin signaling pathway

Colorectal cancer

Focal adhesion

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Endocytosis

Ubiquitin mediated proteolysis

Chemokine signaling pathway

Neurotrophin signaling pathway

Pancreatic cancer

Prostate cancer

Endometrial cancer

Calcium signaling pathway

Wnt signaling pathway

Melanoma

Natural killer cell mediated cytotoxicity

Olfactory transduction

Huntington's disease

B cell receptor signaling pathway

ErbB signaling pathway

p53 signaling pathway

Fc epsilon RI signaling pathway

Jak-STAT signaling pathway

Tight junction

Glioma

Progesterone-mediated oocyte maturation

Cell cycle

Chronic myeloid leukemia

T cell receptor signaling pathway

Leukocyte transendothelial migration

Purine metabolism

Alzheimer's disease

Axon guidance

Non-small cell lung cancer

mTOR signaling pathway

Apoptosis

Melanogenesis

GnRH signaling pathway

Vascular smooth muscle contraction

Thyroid cancer

Renal cell carcinoma

Small cell lung cancer

Adherens junction

Gap junction

Cell adhesion molecules (CAMs)

VEGF signaling pathway

Mismatch repair

Toll-like receptor signaling pathway

Fc gamma R-mediated phagocytosis

Bladder cancer

Oocyte meiosis

Type II diabetes mellitus

Acute myeloid leukemia

Long-term depression

Lysosome

Dilated cardiomyopathy

Long-term potentiation

Glycolysis / Gluconeogenesis

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Hematopoietic cell lineage

Primary immunodeficiency

Hypertrophic cardiomyopathy (HCM)

Parkinson's disease

Spliceosome

Phosphatidylinositol signaling system

Starch and sucrose metabolism

Adipocytokine signaling pathway

Amino sugar and nucleotide sugar metabolism

Basal cell carcinoma

Amyotrophic lateral sclerosis (ALS)

Oxidative phosphorylation

Systemic lupus erythematosus

TGF-beta signaling pathway

Pyrimidine metabolism

Homologous recombination

PPAR signaling pathway

Viral myocarditis

Galactose metabolism

Maturity onset diabetes of the young

Epithelial cell signaling in Helicobacter pylori infection

Antigen processing and presentation

RIG-I-like receptor signaling pathway

NOD-like receptor signaling pathway

Inositol phosphate metabolism

Notch signaling pathway

ECM-receptor interaction

Dorso-ventral axis formation

Vibrio cholerae infection

Complement and coagulation cascades

Pathogenic Escherichia coli infection

Cardiac muscle contraction

Glycerophospholipid metabolism

Ribosome

Drug metabolism - cytochrome P450

Metabolism of xenobiotics by cytochrome P450

Cytosolic DNA-sensing pathway

Hedgehog signaling pathway

Arginine and proline metabolism

Taste transduction

Retinol metabolism

Drug metabolism - other enzymes

RNA degradation

Nucleotide excision repair

Valine

Glutathione metabolism

Arachidonic acid metabolism

Citrate cycle (TCA cycle)

N-Glycan biosynthesis

Tyrosine metabolism

Autoimmune thyroid disease

Pyruvate metabolism

Lysine degradation

Fatty acid metabolism

Glycerolipid metabolism

Sphingolipid metabolism

leucine and isoleucine degradation

Prion diseases

ABC transporters

Proteasome

Base excision repair

Type I diabetes mellitus

Tryptophan metabolism

Cysteine and methionine metabolism

Graft-versus-host disease

Fructose and mannose metabolism

SNARE interactions in vesicular transport

Androgen and estrogen metabolism

Porphyrin and chlorophyll metabolism

Ether lipid metabolism

Alanine

aspartate and glutamate metabolism

Allograft rejection

Propanoate metabolism

DNA replication

Aminoacyl-tRNA biosynthesis

Glycosphingolipid biosynthesis - lacto and neolacto series

Glycine

serine and threonine metabolism

Butanoate metabolism

Regulation of autophagy

Histidine metabolism

Basal transcription factors

Pentose phosphate pathway

Nitrogen metabolism

Selenoamino acid metabolism

Glycosaminoglycan degradation

Linoleic acid metabolism

O-Glycan biosynthesis

Phenylalanine metabolism

RNA polymerase

Nicotinate and nicotinamide metabolism

Asthma

Pentose and glucuronate interconversions

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

beta-Alanine metabolism

Biosynthesis of unsaturated fatty acids

Heparan sulfate biosynthesis

Ascorbate and aldarate metabolism

Keratan sulfate biosynthesis

Primary bile acid biosynthesis

One carbon pool by folate

Pantothenate and CoA biosynthesis

Riboflavin metabolism

Steroid biosynthesis

Renin-angiotensin system

Other glycan degradation

alpha-Linolenic acid metabolism

Chondroitin sulfate biosynthesis

Non-homologous end-joining

Glycosphingolipid biosynthesis - globo series

Sulfur metabolism

Terpenoid backbone biosynthesis

Glycosphingolipid biosynthesis - ganglio series

Glyoxylate and dicarboxylate metabolism

Circadian rhythm - mammal

Limonene and pinene degradation

leucine and isoleucine biosynthesis

Taurine and hypotaurine metabolism

Cyanoamino acid metabolism

C21-Steroid hormone metabolism

Protein export

Folate biosynthesis

Thiamine metabolism

Caffeine metabolism

Fatty acid elongation in mitochondria

Synthesis and degradation of ketone bodies

Methane metabolism

Fatty acid biosynthesis

Ubiquinone and other terpenoid-quinone biosynthesis

Lipoic acid metabolism

Lysine biosynthesis

O-Mannosyl glycan biosynthesis

Phenylalanine

tyrosine and tryptophan biosynthesis

Vitamin B6 metabolism

D-Glutamine and D-glutamate metabolism

Biotin metabolism

D-Arginine and D-ornithine metabolism

Neomycin

Puromycin

None

1

Yes

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