Proteins

Proteins

CytoSections

Human

TCF7L2

JNK1

JNK2

P53

AKT1

BETA CATENIN

BIRC5

ERK1

LEF1

SMAD2

ACTIVIN A RECEPTOR TYPE IC

AXIN 1

BAD

BAX

BCL2

CASPASE 3

CASPASE 9

DVL1

EGFR

ERK2

FRIZZLED 6

GRB2

GSK3 BETA

KRAS

PI 3 KINASE P55 GAMMA

PIK3R5

RAC1

SMAD3

TGF BETA 2

ACTIVIN A RECEPTOR TYPE IB

AKT2

AKT3

APC

ARAF

AXIN2

B RAF

CCND1

CYCS

DCC

DVL2

FOS

FZD10

FZD4

FZD5

FZD9

IGF1R

JNK3

JUN

MEK1

MET

MLH1

MSH2

MSH3

MYC

PDGFRA

PDGFRB

PI 3 KINASE P85 ALPHA

PIK3CD

PIK3CG

PIK3R2

RAC2

RAC3

RAF1

SMAD4

TCF7

TGF BETA RECEPTOR I

TGF BETA RECEPTOR II

TGFB3

HEK293T

C-Myc/DDK

C-MYC/DDK

His-tag

N-His

Tag Free

C-DDK

C-His

C-DDK/His

C-6His

C-Fc

N-GST and C-His

hIgG-His-tag

C-HIS

N-AVI

N-DDK

N-FUSION

N-GST and C-HIS

N-His-GST

Druggable Genome

ES Cell Differentiation/IPS

Protein Kinase

Transcription Factors

Transmembrane

Stem cell - Pluripotency

Stem cell relevant signaling - JAK/STAT signaling pathway

Cancer stem cells

Embryonic stem cells

GPCR

Stem cell relevant signaling - TGFb/BMP signaling pathway

Adult stem cells

Secreted Protein

Protease

Stem cell relevant signaling - Wnt Signaling pathway

Induced pluripotent stem cells

Stem cell relevant signaling - DSL/Notch pathway

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Regulation of actin cytoskeleton

Chemokine signaling pathway

Focal adhesion

Neurotrophin signaling pathway

Calcium signaling pathway

Jak-STAT signaling pathway

Wnt signaling pathway

Insulin signaling pathway

Cell cycle

T cell receptor signaling pathway

Progesterone-mediated oocyte maturation

ErbB signaling pathway

Natural killer cell mediated cytotoxicity

Endocytosis

Purine metabolism

Oocyte meiosis

Apoptosis

Hematopoietic cell lineage

Prostate cancer

Toll-like receptor signaling pathway

Axon guidance

GnRH signaling pathway

Colorectal cancer

Alzheimer's disease

Ubiquitin mediated proteolysis

Melanogenesis

Pancreatic cancer

Adherens junction

Leukocyte transendothelial migration

Tight junction

Vascular smooth muscle contraction

Small cell lung cancer

Gap junction

TGF-beta signaling pathway

Chronic myeloid leukemia

Lysosome

Fc epsilon RI signaling pathway

Huntington's disease

Renal cell carcinoma

Cell adhesion molecules (CAMs)

Dilated cardiomyopathy

Glioma

Melanoma

VEGF signaling pathway

B cell receptor signaling pathway

Hypertrophic cardiomyopathy (HCM)

Acute myeloid leukemia

Adipocytokine signaling pathway

Long-term potentiation

Complement and coagulation cascades

Fc gamma R-mediated phagocytosis

p53 signaling pathway

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Endometrial cancer

NOD-like receptor signaling pathway

Non-small cell lung cancer

Phosphatidylinositol signaling system

Long-term depression

Olfactory transduction

RIG-I-like receptor signaling pathway

Amyotrophic lateral sclerosis (ALS)

Glycolysis / Gluconeogenesis

ECM-receptor interaction

Epithelial cell signaling in Helicobacter pylori infection

PPAR signaling pathway

Bladder cancer

Inositol phosphate metabolism

Pathogenic Escherichia coli infection

Thyroid cancer

Antigen processing and presentation

Drug metabolism - cytochrome P450

mTOR signaling pathway

Cardiac muscle contraction

Metabolism of xenobiotics by cytochrome P450

Type II diabetes mellitus

Valine

Basal cell carcinoma

Cytosolic DNA-sensing pathway

Hedgehog signaling pathway

Pyrimidine metabolism

Arginine and proline metabolism

Parkinson's disease

Primary immunodeficiency

Retinol metabolism

leucine and isoleucine degradation

Viral myocarditis

Drug metabolism - other enzymes

Glycerophospholipid metabolism

Glycerolipid metabolism

Nucleotide excision repair

Tyrosine metabolism

Base excision repair

Prion diseases

Arachidonic acid metabolism

Fructose and mannose metabolism

Taste transduction

Vibrio cholerae infection

Autoimmune thyroid disease

Pyruvate metabolism

Fatty acid metabolism

SNARE interactions in vesicular transport

Sphingolipid metabolism

Systemic lupus erythematosus

Lysine degradation

Notch signaling pathway

Amino sugar and nucleotide sugar metabolism

Butanoate metabolism

Starch and sucrose metabolism

Galactose metabolism

Glutathione metabolism

Proteasome

Tryptophan metabolism

Androgen and estrogen metabolism

Pentose phosphate pathway

Regulation of autophagy

Alanine

Cysteine and methionine metabolism

Histidine metabolism

aspartate and glutamate metabolism

Linoleic acid metabolism

Propanoate metabolism

Type I diabetes mellitus

Oxidative phosphorylation

Ether lipid metabolism

Homologous recombination

Maturity onset diabetes of the young

Ribosome

Citrate cycle (TCA cycle)

Nitrogen metabolism

Porphyrin and chlorophyll metabolism

Mismatch repair

Aminoacyl-tRNA biosynthesis

Dorso-ventral axis formation

Glycosaminoglycan degradation

Phenylalanine metabolism

Renin-angiotensin system

Spliceosome

beta-Alanine metabolism

Allograft rejection

DNA replication

Pantothenate and CoA biosynthesis

Riboflavin metabolism

ABC transporters

Selenoamino acid metabolism

C21-Steroid hormone metabolism

Other glycan degradation

leucine and isoleucine biosynthesis

Glycine

Non-homologous end-joining

serine and threonine metabolism

Circadian rhythm - mammal

Graft-versus-host disease

Asthma

Folate biosynthesis

N-Glycan biosynthesis

Primary bile acid biosynthesis

alpha-Linolenic acid metabolism

Basal transcription factors

Steroid biosynthesis

Terpenoid backbone biosynthesis

Pentose and glucuronate interconversions

Synthesis and degradation of ketone bodies

Ascorbate and aldarate metabolism

Glycosphingolipid biosynthesis - globo series

Glyoxylate and dicarboxylate metabolism

Limonene and pinene degradation

RNA degradation

One carbon pool by folate

Thiamine metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Nicotinate and nicotinamide metabolism

Sulfur metabolism

Biosynthesis of unsaturated fatty acids

Caffeine metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Fatty acid elongation in mitochondria

Methane metabolism

Taurine and hypotaurine metabolism

Fatty acid biosynthesis

Glycosphingolipid biosynthesis - ganglio series

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Heparan sulfate biosynthesis

Phenylalanine

Protein export

RNA polymerase

tyrosine and tryptophan biosynthesis

O-Glycan biosynthesis

Vitamin B6 metabolism

Biotin metabolism

Chondroitin sulfate biosynthesis

D-Arginine and D-ornithine metabolism

D-Glutamine and D-glutamate metabolism

Keratan sulfate biosynthesis

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