Proteins

Proteins

Over-expression Lysates

Human

AKR1D1

AROMATASE

CYP11B1

HSD11B1

LCMT1

UGT

UGT2B10

AKR1C4

BUD23

ESTROGEN SULFOTRANSFERASE

HEMK1

HSD11B2

HSD17B2

HSD17B3

HSD17B7

HSD17B8

HSD3B1

HSD3B2

LCMT2

METHYLTRANSFERASE LIKE 6

METTL2B

SRD5A3

STEROID SULFATASE

SULT2B1

TRM11

UGT1A10

UGT1A3

UGT1A4

UGT1A6

UGT1A8

UGT2A1

WB

HEK293T

C-Myc/DDK

Druggable Genome

Transmembrane

WB

P450

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Regulation of actin cytoskeleton

Neuroactive ligand-receptor interaction

Focal adhesion

Endocytosis

Chemokine signaling pathway

Neurotrophin signaling pathway

Wnt signaling pathway

Purine metabolism

Calcium signaling pathway

Huntington's disease

Alzheimer's disease

Jak-STAT signaling pathway

Ubiquitin mediated proteolysis

Insulin signaling pathway

Axon guidance

Cell cycle

Natural killer cell mediated cytotoxicity

Tight junction

Oocyte meiosis

Leukocyte transendothelial migration

Lysosome

Cell adhesion molecules (CAMs)

Progesterone-mediated oocyte maturation

T cell receptor signaling pathway

Olfactory transduction

ErbB signaling pathway

Hematopoietic cell lineage

Spliceosome

Systemic lupus erythematosus

Melanogenesis

Toll-like receptor signaling pathway

GnRH signaling pathway

Apoptosis

Prostate cancer

Vascular smooth muscle contraction

Fc gamma R-mediated phagocytosis

Parkinson's disease

Dilated cardiomyopathy

Oxidative phosphorylation

Adherens junction

Pyrimidine metabolism

Antigen processing and presentation

Colorectal cancer

Hypertrophic cardiomyopathy (HCM)

Small cell lung cancer

Pancreatic cancer

TGF-beta signaling pathway

VEGF signaling pathway

Gap junction

Melanoma

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

B cell receptor signaling pathway

Fc epsilon RI signaling pathway

Chronic myeloid leukemia

Complement and coagulation cascades

PPAR signaling pathway

Renal cell carcinoma

Glioma

p53 signaling pathway

Adipocytokine signaling pathway

Ribosome

Acute myeloid leukemia

Long-term potentiation

Glycolysis / Gluconeogenesis

Phosphatidylinositol signaling system

RIG-I-like receptor signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

Cardiac muscle contraction

Long-term depression

NOD-like receptor signaling pathway

Pathogenic Escherichia coli infection

Glycerophospholipid metabolism

Non-small cell lung cancer

Viral myocarditis

ECM-receptor interaction

Endometrial cancer

Drug metabolism - cytochrome P450

Metabolism of xenobiotics by cytochrome P450

Vibrio cholerae infection

Amyotrophic lateral sclerosis (ALS)

Cytosolic DNA-sensing pathway

Valine

Arginine and proline metabolism

mTOR signaling pathway

Hedgehog signaling pathway

Inositol phosphate metabolism

Basal cell carcinoma

Drug metabolism - other enzymes

RNA degradation

Thyroid cancer

leucine and isoleucine degradation

Retinol metabolism

Amino sugar and nucleotide sugar metabolism

Bladder cancer

Glutathione metabolism

Proteasome

Starch and sucrose metabolism

Arachidonic acid metabolism

Autoimmune thyroid disease

Pyruvate metabolism

Type II diabetes mellitus

Nucleotide excision repair

Fatty acid metabolism

Glycerolipid metabolism

Tyrosine metabolism

Notch signaling pathway

Taste transduction

Primary immunodeficiency

SNARE interactions in vesicular transport

Tryptophan metabolism

Type I diabetes mellitus

Alanine

Graft-versus-host disease

Sphingolipid metabolism

aspartate and glutamate metabolism

Lysine degradation

Base excision repair

Butanoate metabolism

Cysteine and methionine metabolism

Fructose and mannose metabolism

Prion diseases

N-Glycan biosynthesis

Glycosphingolipid biosynthesis - lacto and neolacto series

Aminoacyl-tRNA biosynthesis

Androgen and estrogen metabolism

Citrate cycle (TCA cycle)

DNA replication

Pentose phosphate pathway

Propanoate metabolism

Allograft rejection

Ether lipid metabolism

Porphyrin and chlorophyll metabolism

Glycine

Regulation of autophagy

serine and threonine metabolism

Histidine metabolism

Galactose metabolism

O-Glycan biosynthesis

Selenoamino acid metabolism

Basal transcription factors

Nitrogen metabolism

Homologous recombination

Linoleic acid metabolism

Nicotinate and nicotinamide metabolism

Asthma

Glycosaminoglycan degradation

Maturity onset diabetes of the young

RNA polymerase

Dorso-ventral axis formation

beta-Alanine metabolism

Mismatch repair

Sulfur metabolism

Phenylalanine metabolism

Primary bile acid biosynthesis

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Heparan sulfate biosynthesis

Pantothenate and CoA biosynthesis

Biosynthesis of unsaturated fatty acids

Pentose and glucuronate interconversions

Riboflavin metabolism

Keratan sulfate biosynthesis

Terpenoid backbone biosynthesis

One carbon pool by folate

Other glycan degradation

alpha-Linolenic acid metabolism

Ascorbate and aldarate metabolism

Chondroitin sulfate biosynthesis

Glycosphingolipid biosynthesis - globo series

Renin-angiotensin system

Glyoxylate and dicarboxylate metabolism

Non-homologous end-joining

leucine and isoleucine biosynthesis

ABC transporters

C21-Steroid hormone metabolism

Glycosphingolipid biosynthesis - ganglio series

Steroid biosynthesis

Circadian rhythm - mammal

Taurine and hypotaurine metabolism

Caffeine metabolism

Folate biosynthesis

Limonene and pinene degradation

Thiamine metabolism

Cyanoamino acid metabolism

Fatty acid elongation in mitochondria

Synthesis and degradation of ketone bodies

Protein export

Ubiquinone and other terpenoid-quinone biosynthesis

Fatty acid biosynthesis

Methane metabolism

Lipoic acid metabolism

D-Glutamine and D-glutamate metabolism

Lysine biosynthesis

Phenylalanine

Vitamin B6 metabolism

tyrosine and tryptophan biosynthesis

O-Mannosyl glycan biosynthesis

Biotin metabolism

D-Arginine and D-ornithine metabolism

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Yes