Proteins

Proteins

CytoSections

Human

TCF7L2

JNK1

JNK2

P53

AKT1

BETA CATENIN

BIRC5

ERK1

LEF1

SMAD2

ACTIVIN A RECEPTOR TYPE IC

AXIN 1

BAD

BAX

BCL2

CASPASE 3

CASPASE 9

DVL1

EGFR

ERK2

FRIZZLED 6

GRB2

GSK3 BETA

KRAS

PI 3 KINASE P55 GAMMA

PIK3R5

RAC1

RALGDS

SMAD3

TGF BETA 2

ACTIVIN A RECEPTOR TYPE IB

AKT2

AKT3

APC

APPL1

ARAF

AXIN2

B RAF

CCND1

CYCS

DCC

DVL2

FOS

FZD10

FZD4

FZD5

FZD9

IGF1R

JNK3

JUN

MEK1

MET

MLH1

MSH2

MSH3

MYC

PDGFRA

PDGFRB

PI 3 KINASE P85 ALPHA

PIK3CD

PIK3CG

PIK3R2

RAC2

RAC3

RAF1

SMAD4

TCF7

TGF BETA RECEPTOR I

TGF BETA RECEPTOR II

TGFB3

HEK293T

C-Myc/DDK

C-MYC/DDK

His-tag

N-His

Tag Free

C-DDK

C-His

C-DDK/His

C-6His

C-Fc

N-GST and C-His

hIgG-His-tag

C-HIS

N-AVI

N-DDK

N-FUSION

N-GST and C-HIS

N-His-GST

Druggable Genome

ES Cell Differentiation/IPS

Protein Kinase

Transcription Factors

Transmembrane

Stem cell - Pluripotency

Stem cell relevant signaling - JAK/STAT signaling pathway

Cancer stem cells

Embryonic stem cells

GPCR

Stem cell relevant signaling - TGFb/BMP signaling pathway

Adult stem cells

Secreted Protein

Protease

Stem cell relevant signaling - Wnt Signaling pathway

Induced pluripotent stem cells

Stem cell relevant signaling - DSL/Notch pathway

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Regulation of actin cytoskeleton

Neuroactive ligand-receptor interaction

Focal adhesion

Endocytosis

Chemokine signaling pathway

Neurotrophin signaling pathway

Wnt signaling pathway

Purine metabolism

Calcium signaling pathway

Huntington's disease

Alzheimer's disease

Ubiquitin mediated proteolysis

Jak-STAT signaling pathway

Insulin signaling pathway

Axon guidance

Cell cycle

Natural killer cell mediated cytotoxicity

Oocyte meiosis

Tight junction

Leukocyte transendothelial migration

Progesterone-mediated oocyte maturation

Lysosome

T cell receptor signaling pathway

Cell adhesion molecules (CAMs)

Olfactory transduction

ErbB signaling pathway

Systemic lupus erythematosus

Spliceosome

Hematopoietic cell lineage

Melanogenesis

Toll-like receptor signaling pathway

GnRH signaling pathway

Prostate cancer

Apoptosis

Vascular smooth muscle contraction

Fc gamma R-mediated phagocytosis

Parkinson's disease

Oxidative phosphorylation

Adherens junction

Antigen processing and presentation

Colorectal cancer

Pyrimidine metabolism

Dilated cardiomyopathy

Hypertrophic cardiomyopathy (HCM)

Pancreatic cancer

Small cell lung cancer

TGF-beta signaling pathway

VEGF signaling pathway

Melanoma

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

B cell receptor signaling pathway

Fc epsilon RI signaling pathway

Gap junction

Chronic myeloid leukemia

Renal cell carcinoma

Glioma

Complement and coagulation cascades

PPAR signaling pathway

Ribosome

p53 signaling pathway

Adipocytokine signaling pathway

Acute myeloid leukemia

Long-term potentiation

Glycolysis / Gluconeogenesis

Phosphatidylinositol signaling system

RIG-I-like receptor signaling pathway

Cardiac muscle contraction

Epithelial cell signaling in Helicobacter pylori infection

Long-term depression

NOD-like receptor signaling pathway

Pathogenic Escherichia coli infection

Endometrial cancer

Glycerophospholipid metabolism

Non-small cell lung cancer

Viral myocarditis

Drug metabolism - cytochrome P450

ECM-receptor interaction

Metabolism of xenobiotics by cytochrome P450

Amyotrophic lateral sclerosis (ALS)

Valine

Arginine and proline metabolism

Cytosolic DNA-sensing pathway

Vibrio cholerae infection

mTOR signaling pathway

Hedgehog signaling pathway

Inositol phosphate metabolism

Basal cell carcinoma

Drug metabolism - other enzymes

RNA degradation

Thyroid cancer

leucine and isoleucine degradation

Bladder cancer

Glutathione metabolism

Retinol metabolism

Amino sugar and nucleotide sugar metabolism

Proteasome

Arachidonic acid metabolism

Autoimmune thyroid disease

Pyruvate metabolism

Starch and sucrose metabolism

Type II diabetes mellitus

Glycerolipid metabolism

Fatty acid metabolism

Nucleotide excision repair

Tyrosine metabolism

Notch signaling pathway

Primary immunodeficiency

SNARE interactions in vesicular transport

Taste transduction

Tryptophan metabolism

Type I diabetes mellitus

Alanine

Lysine degradation

Sphingolipid metabolism

aspartate and glutamate metabolism

Butanoate metabolism

Cysteine and methionine metabolism

Fructose and mannose metabolism

Graft-versus-host disease

Base excision repair

N-Glycan biosynthesis

Prion diseases

Androgen and estrogen metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Aminoacyl-tRNA biosynthesis

Citrate cycle (TCA cycle)

Ether lipid metabolism

Pentose phosphate pathway

Porphyrin and chlorophyll metabolism

Propanoate metabolism

DNA replication

Allograft rejection

Glycine

Regulation of autophagy

serine and threonine metabolism

Histidine metabolism

Galactose metabolism

O-Glycan biosynthesis

Selenoamino acid metabolism

Basal transcription factors

Nitrogen metabolism

Linoleic acid metabolism

Asthma

Dorso-ventral axis formation

Nicotinate and nicotinamide metabolism

Glycosaminoglycan degradation

Maturity onset diabetes of the young

RNA polymerase

Homologous recombination

beta-Alanine metabolism

Phenylalanine metabolism

Sulfur metabolism

Mismatch repair

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Heparan sulfate biosynthesis

Primary bile acid biosynthesis

Biosynthesis of unsaturated fatty acids

Pantothenate and CoA biosynthesis

Pentose and glucuronate interconversions

Keratan sulfate biosynthesis

Riboflavin metabolism

Terpenoid backbone biosynthesis

One carbon pool by folate

Other glycan degradation

alpha-Linolenic acid metabolism

Ascorbate and aldarate metabolism

Chondroitin sulfate biosynthesis

Glycosphingolipid biosynthesis - globo series

Glyoxylate and dicarboxylate metabolism

Renin-angiotensin system

leucine and isoleucine biosynthesis

ABC transporters

C21-Steroid hormone metabolism

Glycosphingolipid biosynthesis - ganglio series

Non-homologous end-joining

Steroid biosynthesis

Circadian rhythm - mammal

Limonene and pinene degradation

Taurine and hypotaurine metabolism

Caffeine metabolism

Folate biosynthesis

Thiamine metabolism

Cyanoamino acid metabolism

Fatty acid elongation in mitochondria

Synthesis and degradation of ketone bodies

Protein export

Ubiquinone and other terpenoid-quinone biosynthesis

Fatty acid biosynthesis

Methane metabolism

Lipoic acid metabolism

D-Glutamine and D-glutamate metabolism

Lysine biosynthesis

Phenylalanine

Vitamin B6 metabolism

tyrosine and tryptophan biosynthesis

O-Mannosyl glycan biosynthesis

Biotin metabolism

D-Arginine and D-ornithine metabolism

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