PPM1G Mouse Monoclonal Antibody [Clone ID: k1G6]

Specifications

Product Data
Clone Name	k1G6
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western blot (1:1,000 - 1:2,000). Immunohistochemistry on paraffin sections (1:50 - 1:100).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human PPM1G (317-546 aa) purified from E. coli
Specificity	The antibody recognizes human PPM1G. Other species not tested.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	protein phosphatase, Mg2+/Mn2+ dependent 1G
Database Link	Entrez Gene 5496 Human UniProt ID O15355
Background	PPM1G (Protein phosphatase 1G) is a member of the PP2C family of Serine/threonine protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. The human Ser/Thr phosphatase PPM1G promotes spliceosome assembly. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome.
Synonyms	Protein phosphatase 2C isoform gamma, Protein phosphatase 1C, PPM1C, PP2C-gamma
Reference Data

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