CD62P (SELP) Mouse Monoclonal Antibody [Clone ID: B-G43]

CAT#: AM31272AF-N

CD62P (SELP) mouse monoclonal antibody, clone B-G43, Azide Free



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CNY 3,806.00


货期*
5周

规格
    • 200 ug

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Specifications

Product Data
Clone Name B-G43
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Recombinant Human CD62P.
Specificity This antibody recognises both natural and recombinant CD62P.
Formulation Phosphate-buffered saline.
Sterile-filtered through 0.22 µm.
Carrier and preservative free
State: Azide Free
State: Liquid purified Ig fraction
Concentration lot specific
Purification Ion Exchange Chromatography
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C.
Gene Name selectin P
Background CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond cluster.
Synonyms SELP, GMRP, GRMP, PADGEM, GMP-140, LECAM3
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs)
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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