Ptprc (CD45RC) Mouse Monoclonal Antibody [Clone ID: HIS25]
CAT#: AM39046SU-N
Ptprc (CD45RC) mouse monoclonal antibody, clone HIS25, Supernatant
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CNY 3,939.00
货期*
5周
规格
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Specifications
Product Data | |
Clone Name | HIS25 |
Applications | IF, IHC |
Recommend Dilution | Flow cytometry. Immunofluorescence. Immunohistochemistry on frozen tissue sections. |
Reactivity | Rat |
Host | Mouse |
Clonality | Monoclonal |
Specificity | The antibody recognizes CD45RC, found on B cells, precursor B cells, subset T cells (not thymocytes). |
Formulation | State: Supernatant State: Liquid cell culture supernatant containing 0.09% sodium azide |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C. |
Gene Name | protein tyrosine phosphatase, receptor type, C |
Database Link | |
Background | The CD45 family of cell surface glycoprotein antigens exist as a set of isoforms. The patterns of monoclonal antibody recognition of the CD45 phenotypes can be restricted (CD45RA, RB and RC), or broader, such as the CD45 T 200 species. The "restricted" subsets of this group arise as a result of translation of alternatively spliced mRNAs from exons A, B and C (exons 4, 5 and 6), where exons 3-15 encode the extracellular domain of the CD45 molecule. The restricted epitopes are differentially expressed on T and B lymphocytes, including functionally distinct T cells. CD45 (LCA) is a transmembrane phosphotyrosine phosphatase expressed on leucocytes. Myeloid cells do not express the RC isoform. |
Synonyms | PTPRC, Leukocyte common antigen, L-CA, T200 |
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