PDE2A Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, IP, WB
Recommend Dilution	Western blot (1/2000 as a guideline). Immunoprecipitation. Immunohistochemistry.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Designed from the C-terminal region common to all known 2A isoforms
Specificity	The antibody selectively detects proteins corresponding to members of the PDE2A sub-family.
Formulation	PBS containing 0.05% Sodium Azide as preservative State: Serum State: Liquid Diluted Serum
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing.
Gene Name	phosphodiesterase 2A
Database Link	Entrez Gene 5138 Human UniProt ID O00408
Background	Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3', 5'-monophosphate (cAMP and cGMP). Thus, these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling. The PDE2 enzyme belongs to a family of PDEs able to hydrolyse both intracellular second messengers, cAMP and cGMP.
Synonyms	CGS-PDE, cGSPDE
Reference Data

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