Annexin V (ANXA5) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	Western blot: 0.5 μg/ml. Immunocytochemistry: 0.5 μg/ml. Immunohistochemistry on Paraffin Sections: 1 μg/ml (Antigen Retrieval by heat).
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide corresponding to a sequence near the C-terminal of Human Annexin V
Specificity	This antibody detects Annexin A5 / ANXA5 near C-term. No cross reactivity with other proteins.
Formulation	5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg Sodium Azide State: Aff - Purified State: Lyophilized purified Ig fraction.
Reconstitution Method	Restore with 0.2 ml of distilled water to a concentration of 0.5 mg/ml.
Purification	Immunoaffinity Chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody after reconstitution at 2-8°C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	annexin A5
Database Link	Entrez Gene 11747 MouseEntrez Gene 25673 RatEntrez Gene 308 Human UniProt ID P08758
Background	Annexin V also know as endonnexin II(ENX2),or placental protein 4 (PP4). Endonexin II is a member of the family of Ca(2+)-dependent phospholipid binding proteins, known as annexins. It bind to the phospholipids that are preferentially located on the cytosolic face of the plasma membrane. It has a relative molecular weight of about 35,000. The gene lies on mouse chromosome 3 in close linkage with the fibroblast growth factor 2 (basic) gene and is syntenic with other genes known to have orthologous counterparts on human chromosome 4q. The PP4 cDNA encoded a protein of 320 amino acid residues.A single mRNA, approximately 1.6 kb long, was found to be expressed in human cell lines and placenta. PP4 is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex,which is involved in the blood coagulation cascade.
Synonyms	Annexin-5, Annexin V, Lipocortin V, Endonexin II, Calphobindin I, Anchorin CII, ANX5, ENX2, PP4, CBP-I, PAP-I, VAC-alpha
Reference Data

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