KDM4C (C-term) Rabbit Polyclonal Antibody
CAT#: AP52272PU-N
KDM4C (C-term) rabbit polyclonal antibody, Aff - Purified
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CNY 6,314.00
货期*
5周
规格
Specifications
Product Data | |
Applications | FC, WB |
Recommend Dilution | ELISA: 1/1000. |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 1030-1056 amino acids from the C-terminal region of human JMJD2C |
Specificity | This antibody recognizes Human JMJD2C / KDM4C (C-term). |
Formulation | PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein A column, followed by peptide affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Gene Name | lysine demethylase 4C |
Database Link | |
Background | This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants. |
Synonyms | GASC1, JHDM3C, KIAA0780, GASC-1 protein |
Note | Molecular Weight: 119982 Da |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
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