Eph receptor A3 (EPHA3) pTyr779/833 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	Immunohistochemistry on paraffin sections: 1:50~1:100 .
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Peptide sequence around phosphorylation site of tyrosine 779/833 (E-A-Y(p)-T-T)/(Q-D-V(p)-I-K) derived from Human EPHA3/4/5 (KLH-conjugated)
Specificity	The antibody detects endogenous levels of EPHA3/4/5 only when phosphorylated at tyrosine 779/833.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Affinity chromatography using epitope-specific peptide
Conjugation	Unconjugated
Storage Condition	Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Predicted Protein Size	110 kDa
Gene Name	EPH receptor A3
Database Link	Entrez Gene 2042 Human UniProt ID P29320
Background	This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands.
Synonyms	Ephrin type-A receptor 3, ETK, ETK1, HEK, TYRO4, EPH-like kinase 4, EK4, EK7, hEK7, EK8, hEK4, hEK8Human embryo kinase, TYRO1,SEK, EPHA3, EPHA4, EPHA5
Reference Data

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