SCUBE1 Rabbit Polyclonal Antibody
CNY 5,808.00
CNY 4,840.00
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | IF, WB |
Recommend Dilution | WB: 1 ug/mL, ICC: 20 ug/mL, IF: 20 ug/mL |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | SCUBE1 antibody was raised against a 14 amino acid synthetic peptide near the center of human SCUBE1. |
Formulation | SCUBE1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Concentration | 1ug/ul |
Purification | SCUBE1 Antibody is affinity chromatography purified via peptide column. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | signal peptide, CUB domain and EGF like domain containing 1 |
Database Link | |
Background | SCUBE1 Antibody: SCUBE1 is an EGF-related protein with a CUB (C1s-like) domain that is expressed primarily in the developing gonad, nervous system, somites, surface ectoderm and limb buds. The N-terminal EGF-like repeats of SCUBE1 participate in the formation of adhesions in a Ca2+-dependent fashion. In contrast, the C-terminal cysteine-rich motifs and CUB domain can directly bind and antagonize bone morphogenic protein activity; genetic ablation of this region resulted in brain malformation in mice embryos, suggesting SCUBE1 plays a role in brain morphogenesis. SCUBE1 has also been implicated in early craniofacial development in mice. |
Synonyms | SCUBE1 |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
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