Nogo A (RTN4) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	ELISA: 1:2000-10000, WB: 1:500-2000, IHC: 1:50-200
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 1179-1194 amino acids of Human reticulon 4
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	40 kDa
Gene Name	reticulon 4
Database Link	NP_008939 Entrez Gene 68585 MouseEntrez Gene 83765 RatEntrez Gene 57142 Human UniProt ID Q9NQC3
Background	This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum; and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified.
Synonyms	250; ASY; Nbla00271; Nbla10545; NI220; NOGO; NOGO-A; Nogo-B; Nogo-C; NOGOC; NSP; NSP-CL; RTN-X; RTN4-A
Reference Data
Protein Families	Transmembrane

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