HBA1 Rabbit Monoclonal Antibody [Clone ID: EPR3608]
CAT#: TA327690
Rabbit Monoclonal Hemoglobin A Antibody
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CNY 10,406.00
货期*
5周
规格
经常一起买 (2)
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Specifications
Product Data | |
Clone Name | EPR3608 |
Applications | IHC |
Recommend Dilution | IHC: 1:100 - 1:500 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal |
Formulation | This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | hemoglobin subunit alpha 1 |
Database Link | |
Synonyms | HBA-T3; HBH |
Note | Hemoglobin alpha chain belongs to the globin family and is involved in oxygen transport from the lung to the various peripheral tissues. Hemoglobin A is comprised of two alpha chains and two beta chains, whereas hemoglobin A2 is comprised of two alpha chains and two delta chains.Immunohistochemical localization of hemoglobin is excellent as an erythroid marker for the detection of immature, dysplastic, and megaloblastic erythroid cells in myeloproliferative disorders, such as erythroleukemia. In contrast, myeloid cells, lymphoid cells, plasma cells, histiocytes, and megakaryocytes stain negative with anti-hemoglobin A. Anti-hemoglobin A, combined with antibodies against CD34, CD117, CD68, and MPO can be helpful in distinguishing between reactive extramedullary hematopoiesis and that seen in neoplastic myeloid disorders in spleen. Anti-hemoglobin A is limited to expression by erythroid precursors in bone marrow and is therefore of assistance in calculating percentages of erythroid precursors. |
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