Acetylated Lysine Mouse Monoclonal Antibody [Clone ID: 15G10] Mouse Monoclonal Antibody [Clone ID: 15G10]
CAT#: TA327982
Mouse Monoclonal anti-Acetylated Lysine Antibody
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CNY 4,103.00
货期*
5周
规格
经常一起买 (1)
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Specifications
Product Data | |
Clone Name | 15G10 |
Applications | IF, WB |
Recommend Dilution | WB, IF |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Acetylated protein mixture |
Formulation | This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
Concentration | lot specific |
Purification | The antibody was purified by affinity chromatography. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Background | Proteins are reversibly and dynamically acetylated on the ε-amino group of lysine by acetyltransferases and deacetylated by deacetylases. This post-translational modification can regulate protein function (interactions with other proteins and DNA binding). Histones and transcription factors (PCAF, p53, p300, etc) appear to be the major targets of acetytransferases. Acetylation is usually associated with chromatin remodeling and transcriptional activation, although in some cases (telomeres) it is associated with gene silencing. The 15G10 antibody recognizes acetylated lysine residues on proteins. |
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