P2Y11 (P2RY11) Rabbit Polyclonal Antibody
CAT#: TA328678
Rabbit Polyclonal Anti-P2Y11 Receptor
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CNY 11,000.00
货期*
7周
规格
经常一起买 (1)
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Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommend Dilution | WB: 1:200-1:2000; IHC: 1:100-1:3,000; FC: 1:50-1:600 |
Reactivity | Human, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Peptide (C)NATAAPKPSEPQSRELS, corresponding to amino acid residues 357-373 of human P2Y11. Intracellular, C-terminus. |
Formulation | Lyophilized. Concentration before lyophilization ~0.8mg/ml (lot dependent, please refer to CoA along with shipment for actual concentration). Buffer before lyophilization: phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3. |
Reconstitution Method | Add 50 ul double distilled water (DDW) to the lyophilized powder. |
Purification | Affinity purified on immobilized antigen. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | purinergic receptor P2Y11 |
Database Link | |
Background | The P2Y receptors belong to the G-protein coupled receptors superfamily.They mediate the actions of the extracellular nucleotides (ATP, ADP, UTP and UDP). Eight functional mammalian P2Y receptors have been described: P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, P2Y13, and the UDP-glucose receptor, now renamed P2Y14.The human P2Y11 receptor is unique among the P2Y receptors since it is dually coupled to phospholipase C and adenylyl cyclase. P2Y11 receptor is highly pressed in spleen and for much lower extent at platelets.Expression of P2Y11 receptor was also shown in endothelial cells. In granulocytes HL-60), P2Y11 receptor is thought to have a role in granulocytic differentiation. |
Synonyms | P2Y11 |
Reference Data | |
Protein Families | Druggable Genome, GPCR, Transmembrane |
Protein Pathways | Neuroactive ligand-receptor interaction |
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