IFIT3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, IHC: 5 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	IFIT3 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human IFIT3.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	IFIT3 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 54 kDa; Observed: 50 kDa
Gene Name	interferon induced protein with tetratricopeptide repeats 3
Database Link	NP_001026853 Entrez Gene 3437 Human UniProt ID O14879
Background	The interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) protein is a member of a family of tetratricopeptide repeat-containing proteins whose transcription is upregulated by interferons, virus infection, and molecular patterns such as dsRNA or lipopolysaccharides (1,2). These proteins have been suggested to induce anti-viral cellular activities in response to infection (2). IFIT3 has been shown to interact with TBK1 following RNA virus infection, thereby bridging TBK1 to VISA on the mitochondrion and activating IRF3 and thus the immune response (3).
Synonyms	CIG-49; GARG-49; IFI60; IFIT4; IRG2; ISG60; P60; RIG-G
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.