CASC3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: 293T and A549 cells IHC: 25-100 Positive control: Human brain Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human CASC3
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	76 kDa
Gene Name	cancer susceptibility candidate 3
Database Link	NP_031385 Entrez Gene 259170 RatEntrez Gene 22794 Human UniProt ID O15234
Background	The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the Cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles.
Synonyms	BTZ; MLN51
Reference Data

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