SKAR (POLDIP3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 200-1000 WB positive control: TM4 cell
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human POLDIP3
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	46 kDa
Gene Name	polymerase (DNA) delta interacting protein 3
Database Link	Entrez Gene 84271 Human UniProt ID Q9BY77
Background	POLDIP3 (polymerase delta-interacting protein 3), also known as SKAR or PDIP46, is a 421 amino acid nuclear protein. POLDIP3 interacts with DNA pol ∂ 2, a protein essential to DNA replication, recombination and repair. POLDIP3 is a substrate for the signaling intermediate Rsk-1 and is thought to regulate cell growth. POLDIP3 contains one RRM (RNA recognition motif) domain and is phosphorylated upon DNA damage. POLDIP3 is ubiquitously expressed with highest levels found in heart, kidney, skeletal muscle and brain. Due to alternative splicing, POLDIP3 is expressed as two isoforms.
Synonyms	KIAA1649; p46; PDIP46; SKAR
Reference Data

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