Mouse Crlf2 ELISA KIT (1 x 96 wells)
CAT#: EA102478
For Quantitative Detection of mouse CRLF2 in cell culture supernates, serum and plasma (heparin, EDTA).
CNY 5,000.00
货期*
3周
规格
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Specifications
Product Data | |
Description | For Quantitative Detection of mouse CRLF2 in cell culture supernates, serum and plasma (heparin, EDTA). |
Size | 1 x 96 wells |
Format | 8x12 divisible strips |
Assay Type | Sandwich ELISA kit of Quantitative Detection for Mouse CRLF2 |
Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 125pg/ml-8000pg/ml |
Specificity | This kit is used for quantitative detection of Mouse CRLF2 |
Sensitivity | <10pg/ml |
Reactivity | Mouse |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Components |
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Background | Cytokine receptor-like factor 2, also known as TSLPR or CRL2, is a protein that in humans is encoded by the CRLF2 gene. It is mapped to Xp22.33. The protein encoded by this gene is a receptor for thymic stromal lymphopoietin(TSLP). Together with the interleukin 7 receptor(IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Two transcript variants encoding different isoforms have been found for this gene. In addition to it, it has been found that rearrangement of CRLF2 and JAK mutation together contribute to leukemogenesis in B-progenitor ALL. |
Gene Symbol | Crlf2 |
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