Human TIM 1 (HAVCR1) ELISA KIT (96 T)
CNY 3,200.00
货期*
3周
规格
Specifications
Product Data | |
Description | Human TIM-1/KIM Immunoassay |
Size | 96 T |
Format | 96-well strip plate |
Assay Type | Solid Phase Sandwich ELISA |
Assay Length | 4 hours |
Signal | Colorimetric |
Curve Range | 31.25-2000pg/ml |
Sample Type | Serum, plasma, Cell culture supernatant |
Sample Volume | 100 uL |
Specificity | This assay recognizes both natural and recombinant human TIM-1/KIM. |
Sensitivity | 8pg/mL |
Reactivity | Human |
Interference | No significant interference observed with available related molecules. |
Components |
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Background | TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types and epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, and the glycoproteins of a number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate the phagocytosis and clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation and enhances Th2 cytokine production. TIM-1 serves as a cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, and severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in the urine during nephropathy. |
Gene Symbol | HAVCR1 |
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