IL18 (NM_001562) Human 3' UTR Clone

Specifications

Product Data
Product Name	IL18 (NM_001562) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	IGIF; IL-1g; IL-18; IL1F4
ACCN	NM_001562
Insert Size	366 bp
Sequence Data	Insert Sequence (showhide) >SC204570 3’UTR clone of NM_001562 The sequence shown below is from the reference sequence of NM_001562. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ATAATGTTCACTGTTCAAAACGAAGACTAGCTATTAAAATTTCATGCCGGGCGCAGTGGCTCACGCCTG TAATCCCAGCCCTTTGGGAGGCTGAGGCGGGCAGATCACCAGAGGTCAGGTGTTCAAGACCAGCCTGAC CAACATGGTGAAACCTCATCTCTACTAAAAATACAAAAAATTAGCTGAGTGTAGTGACGCATGCCCTCA ATCCCAGCTACTCAAGAGGCTGAGGCAGGAGAATCACTTGCACTCCGGAGGTAGAGGTTGTGGTGAGCC GAGATTGCACCATTGCGCTCTAGCCTGGGCAACAACAGCAAAACTCCATCTCAAAAAATAAAATAAATA AATAAACAAATAAAAAATTCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001562.4
Synonyms	IGIF; IL-1g; IL-18; IL1F4
Summary	The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2020]
Locus ID	3606
MW	13.7

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