Cytochrome P450 2C8 (CYP2C8) (NM_000770) Human 3' UTR Clone

Specifications

Product Data
Product Name	Cytochrome P450 2C8 (CYP2C8) (NM_000770) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CPC8; CYP2C8DM; CYPIIC8; MP-12/MP-20
ACCN	NM_000770
Insert Size	386 bp
Sequence Data	Insert Sequence (showhide) >SC204785 3’UTR clone of NM_000770 The sequence shown below is from the reference sequence of NM_000770. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCATACCAGATCTGCTTCATCCCTGTCTGAAGAATGCTAGCCCATCTGGCTGCCGATCTGCTATCACCT GCAACTCTTTTTTTATCAAGGACATTCCCACTATTATGTCTTCTCTGACCTCTCATCAAATCTTCCCAT TCACTCAATATCCCATAAGCATCCAAACTCCATTAAGGAGAGTTGTTCAGGTCACTGCACAAATATATC TGCAATTATTCATACTCTGTAACACTTGTATTAATTGCTGCATATGCTAATACTTTTCTAATGCTGACT TTTTAATATGTTATCACTGTAAAACACAGAAAAGTGATTAATGAATGATAATTTAGATCCATTTCTTTT GTGAATGTGCTAAATAAAAAGTGTTATTAATTGCTGGTTCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000770.3
Synonyms	CPC8; CYP2C8DM; CYPIIC8; MP-12/MP-20
Summary	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
Locus ID	1558
MW	14.7

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