Tcl1 (TCL1A) (NM_001098725) Human 3' UTR Clone

Specifications

Product Data
Product Name	Tcl1 (TCL1A) (NM_001098725) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	TCL1
ACCN	NM_001098725
Insert Size	966 bp
Sequence Data	Insert Sequence (showhide) >SC211175 3’UTR clone of NM_001098725 The sequence shown below is from the reference sequence of NM_001098725. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ATGCTTCTCGAGCTGCTGCCAGATGACTGATGTCTTGGCAGCACCTGTCTCCTTTCACCCCAGGGCCTG AGCCTGGCCAGCCTACAATGGGGATGTTGTGTTTCTGTTCACCTTCGTTTACTATGCCTGTGTCTTCTC CACCACGCTGGGGTCTGGGAGGAATGGACAGACAGAGGATGAGCTCTACCCAGGGCCTGCAGGACCTGC CTGTAGCCCACTCTGCTCGCCTTAGCACTACCACTCCTGCCAAGGAGGATTCCATTTGGCAGAGCTTCT TCCAGGTGCCCAGCTATACCTGTGCCTCGGCTTTTCTCAGCTGGATGATGGTCTTCAGCCTCTTTCTGT CCCTTCTGTCCCTCACAGCACTAGTATTTCATGTTGCACACCCACTCAGCTCCGTGAACTTGTGAGAAC ACAGCCGATTCACCTGAGCAGGACCTCTGAAACCCTGGACCAGTGGTCTCACATGGTGCTACGCCTGCA TGTAAACACGCCTGCAAACGCTGCCTGCCGGTAAACACGCCTGCAAACGCTGCCTGCCCGTAAACACGC CTGCAAACGCTGCCTGCCCACACAGGTTCACGTGCAGCTCAAGGAAAGGCCTGAAAGGAGCCCTTATCT GTGCTCAGGACTCAGAAGCCTCTGGGTCAGTGGTCCACATCCCGGGACGCAGCAGGAGGCCAGGCCGGC GAGCCCTGTGGATGAGCCCTCAGAACCCTTGGCTTGCCCACGTGGAAAAGGGATAGAGGTTGGGTTTCC CCCCTTTTATAGATGGTCACGCACCTGGGTGTTACAAAGTTGTATGTGGCATGAATACTTTTTGTAATG ATTGATTAAATGCAAGATAGTTTATCTAACTTCGTGCGGAATCAGCTTCTATCCTTGACTTAGATTCTG GTGGAGAGAAGTGAGAATAGGCAGCCCCCAAATAAAAAATATTCATGGATTTATTTATTTTCCTTTGGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001098725.2
Synonyms	TCL1
Summary	Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).[supplied by OMIM, Jul 2010]
Locus ID	8115
MW	35.3

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