STIL (NM_001048166) Human 3' UTR Clone

Specifications

Product Data
Product Name	STIL (NM_001048166) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	MCPH7; SIL
ACCN	NM_001048166
Insert Size	1027 bp
Sequence Data	Insert Sequence (showhide) >SC211686 3’UTR clone of NM_001048166 The sequence shown below is from the reference sequence of NM_001048166. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CGTCTCAGACAGTTACCAAAATTATTTTAACCTTTTAACTCCCTGCCCTTTTAATACAGGGACAGGGTG TCTCCTGAAGATACTTAGGGAAAACAGGAGCCTACCACAAGGCTCCTGATCATTCTGGAGTCACTGTTT CTTGGTAGCAGCCAATTGGGAAGAGTGACTTCTGTGAGATGGCTGGCTGGTGATAGGACTAAGTTCTCA TTGTTCAAATAGAGCTGTTCAACATCACTGAAACCTTTAAGAAAAGCCCTGAGATCAGTTATTCCTACA AGTTTAAGTAGTAGACAGATACTATCCAGCTCTAAGTCTCAACTGCTCTTTTATACTGTACTTTTTTTT TTGAGACGGAGTTTTGCTCTTGTAGCCCAGGCTGGAGTGCAATGGCAGGATCTCAGATCACTGCAACCT CTGCCTCCTGGGTTCAAGCGATTTTCCTGCTTCATCTTCCCAGGTAGCTGGGATTACAGGCATGTGCCA CAACGCCTGGCTAATTTTGTATTTTTAGTAGAGACTGGTTTCTCCATGTTGGTCAGGCTGGTCTCAAAC TCCCGACCTCAGGTGATCCGCCCGCCTCGGCCTCCTAAAGTGCTGGGATTACAGGCGTGAGCCACTGCG CCCAGCTATACTGTATATTTTAAGAAGTTCCAGCATGTTGCATCTCTGCATTTATCCTATATCATTAAA AGAACATAAGTTATCATGGTGTTGGGTAAATTAGCGAAATCAACCCTTCCTAAGTTTAAGGGAAAAGTT ATTTTTAAAAACAACTTAATAAAAACTTACACTCTTTTATACAAGAGTGTATTTCCCCTTAATTAGGAT GCATGTTGATTAAACTCGAGATACAGCTTTTTGCAGTATGGTGGGTTGGTTTTGGTGTAACATCTTCAA CATGTCACACTGGCTATCAAAGAATAAGAAAATTATTGAGTATGAGTGTGTTTTATAAACTTTCTGAGT TTTTCAGATGTCTTAATATTTTTTAATAGAACTTAATAAAATGTCTAGATTGACTATTTTC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001048166.1
Synonyms	MCPH7; SIL
Summary	This gene encodes a cytoplasmic protein implicated in regulation of the mitotic spindle checkpoint, a regulatory pathway that monitors chromosome segregation during cell division to ensure the proper distribution of chromosomes to daughter cells. The protein is phosphorylated in mitosis and in response to activation of the spindle checkpoint, and disappears when cells transition to G1 phase. It interacts with a mitotic regulator, and its expression is required to efficiently activate the spindle checkpoint. It is proposed to regulate Cdc2 kinase activity during spindle checkpoint arrest. Chromosomal deletions that fuse this gene and the adjacent locus commonly occur in T cell leukemias, and are thought to arise through illegitimate V-(D)-J recombination events. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Locus ID	6491
MW	39.4

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